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25 Possible Causes for Drug-induced Hypercalcemia, Hypercalciuria

  • Milk-Alkali Syndrome

    The patient presented with a raised serum calcium level without hypercalciuria, nephrocalcinosis and azotaemia.[ncbi.nlm.nih.gov] ., hypercalcemia without hypercalciuria and a normal or high plasma phosphate level.[ncbi.nlm.nih.gov] […] persons with peptic ulcer, in whom, after the ingestion of large amounts of milk and absorbable alkali over many years, a syndrome characterized by hypercalcemia, absence of hypercalciuria[nejm.org]

  • Calcitriol

    Additional endocrine evaluation revealed a normal serum phosphate level, hypercalciuria, and normal serum levels of immunoreactive parathyroid hormone.[ncbi.nlm.nih.gov] Drug: thiazide diuretics may cause hypercalcemia; calcifediol-induced hypercalcemia may precipitate digitalis arrhythmias in patients receiving digitalis glycosides.[robholland.com] Administration of calcitriol, however, may give rise to undesirable side effects, such as hypercalcemia and hypercalciuria.[ncbi.nlm.nih.gov]

  • Vitamin D Toxicity

    Although the hypercalciuria was indistinguishable from the various known forms of idiopathic hypercalciuria, the previous clinical course and the pattern of bone mineral homeostasis[ncbi.nlm.nih.gov] Due to overdosing and higher vitamin D3 content, the infant received 50,000 IU/day for two months resulting in severe hypercalcemia, hypercalciuria and nephrocalcinosis.[ncbi.nlm.nih.gov] The manifestation could be related to hypercalcemia, as in this case.[ 1 ] There may be features of hypercalciuria or metastatic calcification, but in this case they were[ncbi.nlm.nih.gov]

  • Hypercalcemia

    KEYWORDS: Genetics; Hypercalciuria; Osteoporosis; Urolithiasis; Vitamin D[ncbi.nlm.nih.gov] Coccidioidomycosis Histoplasmosis Leprosy Silicosis TB Other disorders Milk-alkali syndrome Vitamin D toxicity Elevated plasma protein concentration: Uncertain mechanism Drugs[web.archive.org] He showed hypercalcemia 3mmol/l and acute, hypovolemic renal failure with profound nephrocalcinosis, but no hypercalciuria.[ncbi.nlm.nih.gov]

  • Hypervitaminosis A

    Hypercalciuria and renal stones. Benign intracranial hypertension.[patient.info] […] cardiovascular events, and more falls and fractures in the elderly. [ 8 ] Presentation Most symptoms occur because of secondary hypercalcaemia with increased bone resorption and hypercalciuria[patient.info]

  • Hypervitaminosis D

    Of the eight patients, seven had hypercalcemia and one had hypercalciuria but normocalcemia (mean serum calcium, 3.14 /- 0.51 mmol per liter [12.6 /- 2.1 mg per deciliter][ncbi.nlm.nih.gov] This was a rare case of drug-induced hypercalcemia resulting from inappropriate iatrogenic supplementation of calcium and Vitamin D.[ssajm.org] […] appetite (anorexia) Dehydration Fatigue Irritability Muscle weakness Vomiting Exams and Tests Excess calcium in the blood ( hypercalcemia ) Excess calcium in the urine (hypercalciuria[indiatoday.in]

  • Hypocalcemic Vitamin D-Dependent Rickets

    Nephrocalcinosis, hypercalciuria, and hypercalcemia can be observed as complications of the therapy.[orpha.net] Drug: thiazide diuretics may cause hypercalcemia; calcifediol-induced hypercalcemia may precipitate digitalis arrhythmias in patients receiving digitalis glycosides.[robholland.com] Hypercalcemia, hypercalciuria, and nephrocalcinosis with reduced renal function may complicate treatment.[merckmanuals.com]

  • Dihydrotachysterol

    The major biological effects of DHT2 administration were hypercalciuria in two subjects and a fall in serum 1,25-dihydroxyvitamin D[1,25-(OH)2D] levels, including free levels[ncbi.nlm.nih.gov] Calcitonin, cholestyramine, prednisone, sodium EDTA and mithramycin have all been used successfully to treat the more resistant cases of vitamin D-induced hypercalcemia.[syrianclinic.com] Hypocalcemia Adult: PO 0.25 mg/d Renal Osteodystrophy Adult: PO 0.1–0.6 mg/d Child: PO 0.1–0.5 mg/d Oral Withhold drug if signs and symptoms of hypercalcemia appear (see[robholland.com]

  • Vitamin D

    Cases of severe PTH-independent hypercalcemia associated with hypercalciuria in infants should prompt genetic analysis of CYP24A1.[ncbi.nlm.nih.gov] Less frequent causes are granulomatous diseases, drug-induced diseases, and intoxications. Case report.[doi.org] All these patients are believed to show hypercalciuria. We report a 24 year old patient of healthy consanguine parents.[ncbi.nlm.nih.gov]

  • Calcifediol

    . • Monitoring urine calcium and urine creatinine may be very helpful in screening for hypercalciuria.[glowm.com] Important Safety Information Back to top Hypercalcemia: Excessive administration of vitamin D compounds, including Rayaldee, can cause hypercalcemia and hypercalciuria.[rayaldee.com] A value above 0.2 suggests hypercalciuria; dose should be decreased regardless of serum calcium level.[glowm.com]

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