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24 Possible Causes for Drug-induced Hyponatraemia

  • Hyponatremia

    Not using MDMA is obviously the best option to prevent MDMA-induced hyponatraemia.[] For patients who are clinically euvolaemic, consider the syndrome of inappropriate diuresis (SIAD), secondary adrenal insufficiency, hypothyroidism as well as drug-induced[] Drug-induced hyperkalemia: old culprits and new offenders. Am J Med 2000 ; 109 : 307 –14. 73 Momi, J, Tang, CM, Abcar, AC, Kujubu, DA, Sim, JJ.[]

  • Hospital Addiction Syndrome

    Presenting with false heart attacks (historically known as cardiopathia fantastica). [ 10 ] Taking drugs to induce side-effects - eg, betablockers to produce bradycardia,[] […] desmopressin to induce hyponatraemia, insulin to induce hypoglycaemia.[]

  • Psychogenic Polydipsia

    Abstract Twenty psychotic patients with psychogenic polydipsia had hyponatremia (98 to 124 mEq/L) lasting up to 28 months, with headache, hypertension, dementia, seizures, lethargy, and coma. Two deaths also may be attributed to this syndrome. Patients drank 7 to 43 L of water daily. Urine was dilute during this[…][]

  • Chlorpropamide

    This represents a drug induced, reversible form of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).[] Abstract This is a report of a patient who developed symptomatic hyponatraemia during chlorpropamide therapy for diabetes mellitus.[]

  • Cyclophosphamide

    Abstract Pancreatoblastoma is a rare tumor of the pancreas in children, with favorable prognosis if completely resected. If unresectable, neoadjuvant chemotherapy with cisplatin-based regimens are commonly used with good response that allows for resection. For locally aggressive or metastatic disease, neoadjuvant[…][]

  • Licorice Ingestion

    Abstract A young woman had an acute embolic episode that affected her right upper limb. An axillo-brachial thromboembolectomy was performed after which distal pulses were recovered. The patient had a long lasting history, longer than ten years, of continuous licorice ingestion. Blood samples showed severe[…][]

  • Loop Diuretic

    Abstract The effect of the loop diuretic, piretanide (12 mg/day on blood pressure and intracellular electrolyte composition in red blood cells during a six-week treatment period was studied in 14 previously untreated essential hypertensive patients. Blood pressure fell continuously during the six weeks, intracellular[…][]

  • Amitriptyline

    OBJECTIVES: Nonpharmacological treatments, such as the Nociceptive Trigeminal Inhibition Tension Suppression System (NTI-tss), are approved for migraine prophylaxis. We aimed at evaluating the effectiveness of the NTI-tss and to compare its efficacy with amitriptyline and with a sham intraoral device in the[…][]

  • Clofibrate

    Abstract Inflammatory and invasive breast cancers are aggressive and require better understanding for the development of new treatments and more accurate prognosis. Here, we detected high expression of PPARα in human primary inflammatory (SUM149PT) and highly invasive (SUM1315MO2) breast cancer cells, and[…][]

  • Carbamazepine

    BACKGROUND: Carbamazepine is a classical anticonvulsant that requires therapeutic drug monitoring. We evaluated the effect of carbamazepine 10, 11 epoxide on a new chemiluminescent immunoassay (CMIA) for application on the Architect i1000SR analyzer. MATERIALS AND METHODS: Carbamazepine concentrations were[…][]

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