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68 Possible Causes for Dry Tap Bone Marrow

  • Primary Myelofibrosis

    This is known as a ‘dry tap’. The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[leukaemia.org.au] […] osteosclerosis with irregular, broad bony trabeculae; markedly dilated sinuses; associated with dry bone marrow taps Spleen : red pulp sinuses contain megakaryocytes, granulocyte[pathologyoutlines.com] When late in the disease progression an attempt is made to take a sample of bone marrow by aspiration, it may result in a dry tap, meaning that where the needle can normally[en.wikipedia.org]

  • Secondary Myelofibrosis

    She was subjected to bone marrow examination. Bone marrow aspiration revealed a dry tap.[ijcasereportsandimages.com] marrow aspiration gives a ‘dry tap’ – no cells are obtained Bone marrow biopsy reveals fibrosis of bone marrow Peripheral smear anemia – normocytic, normochromic leukoerythroblastosis[pgblazer.com] Bone marrow aspiration was not successful due to dry tap while bone marrow biopsy showed grade 2 to 3 reticular fibrosis (Fig. 1 ).[bmccancer.biomedcentral.com]

  • Acute Leukemia

    Bone marrow dry tap is common. Bone marrow biopsy show increased fibroblasts and/or increased reticulin and presence of greater than 30% blast cells.[intechopen.com] […] although on occasion a “dry tap” can also be due to the patient’s marrow pathology.[bcmj.org] Two common problems are a marrow biopsy sample consisting mainly of cortical bone and a hemodilute marrow aspirate lacking marrow particles and consisting mainly of blood,[bcmj.org]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Abstract A previously healthy 11 year-old-white boy presented with persistent mild leukocytosis and a posterior mediastinal mass. Surgical excision of the mass showed it to be a ganglioneuroma. Postoperatively, the patient had marked leukocytosis (white blood cell count 57,000/mm3) and a low leukocyte alkaline[…][ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    The diagnosis is best made on a bone marrow biopsy as an increase in reticulin fibers is present with hairy cell infiltrates in the bone marrow and often results in a "dry[path.upmc.edu] marrow aspirate dry tap due to marrow fibrosis increased reticulin CBC anemia thrombocytopenia leukopenia Differential Diagnosis Non-Hodgkin lymphoma Mantle cell lymphoma[step2.medbullets.com] The extent of bone marrow effacement in hairy cell leukemia is variable.[path.upmc.edu]

  • Acute Panmyelosis with Myelofibrosis

    As a consequence of myelofibrosis and dry tap, bone marrow cytology and cytogenetic analyses are only available in a minority of cases.[bloodjournal.org] Bone marrow aspirate resulted in a dry tap.[ncbi.nlm.nih.gov] Bone marrow aspirate was a dry tap. Bone marrow biopsy showed increased cellularity with panmyelosis [Figure 2].[ajmhs.org]

  • Leukoerythroblastic Anemia

    However, as mentioned, these studies may be difficult to obtain due to “ dry tap ” on bone marrow aspirates in over 50% of patients with primary myelofibrosis.[askhematologist.com] Bone marrow aspiration was a dry tap with poorly cellular touch smears.[ijpmonline.org] […] osteosclerosis with irregular, broad bony trabeculae; markedly dilated sinuses; associated with dry bone marrow taps Spleen : red pulp sinuses contain megakaryocytes, granulocyte[pathologyoutlines.com]

  • Familial Myelofibrosis

    Usually, only a few cells can be obtained by bone marrow aspiration as it results in a dry tap.[symptoma.com] Pancytopenia and leukoerythroblastosis require further clarification and should prompt a bone marrow biopsy.[symptoma.com] The histological examination of bone marrow samples reveals hypocellularity and reduced hematopoiesis as well as generalized fibrosis.[symptoma.com]

  • Acute Megakaryocytic Leukemia

    Bone marrow aspiration returned dry tap. Bone marrow biopsy done showed normal bony trabeculae with fibrotic marrow spaces with normal hematopoisis suppressed.[ijpmonline.org] Bone marrow aspirate was a dry tap. Bone marrow biopsy showed increased cellularity with panmyelosis [Figure 2].[ajmhs.org] The first bone marrow aspirate was a dry tap.[dovepress.com]

  • Myelofibrosis

    This is known as a ‘dry tap’. The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[leukaemia.org.au] When late in the disease progression an attempt is made to take a sample of bone marrow by aspiration, it may result in a dry tap, meaning that where the needle can normally[en.wikipedia.org] Bone marrow examination It is frequently impossible to obtain any samples of bone marrow fluid using a needle and syringe (bone marrow aspiration) due to marrow fibrosis.[leukaemia.org.au]

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