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55 Possible Causes for Dry Tap Bone Marrow, Loss of Appetite

  • Primary Myelofibrosis

    This is known as a ‘dry tap’. The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[] Case 2 This 67 year old female presented with loss of appetite and weight loss of six months duration.[] […] osteosclerosis with irregular, broad bony trabeculae; markedly dilated sinuses; associated with dry bone marrow taps Spleen : red pulp sinuses contain megakaryocytes, granulocyte[]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Chronic myeloid leukemia symptoms Symptoms of CML include: Easy bleeding Unexplained weight loss Fever Loss of appetite Night sweats Pale skin Chronic myeloid leukemia treatment[] Many affected individuals develop an enlarged spleen (splenomegaly), which can cause a feeling of fullness in the abdomen and a loss of appetite.[] The enlarged spleen may put pressure on the stomach causing a loss of appetite and resulting weight loss.[]

  • Acute Leukemia

    Bone marrow dry tap is common. Bone marrow biopsy show increased fibroblasts and/or increased reticulin and presence of greater than 30% blast cells.[] Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[] […] although on occasion a “dry tap” can also be due to the patient’s marrow pathology.[]

  • Secondary Myelofibrosis

    She was subjected to bone marrow examination. Bone marrow aspiration revealed a dry tap.[] Case 2 This 67 year old female presented with loss of appetite and weight loss of six months duration.[] marrow aspiration gives a ‘dry tap’ – no cells are obtained Bone marrow biopsy reveals fibrosis of bone marrow Peripheral smear anemia – normocytic, normochromic leukoerythroblastosis[]

  • Hairy Cell Leukemia

    The diagnosis is best made on a bone marrow biopsy as an increase in reticulin fibers is present with hairy cell infiltrates in the bone marrow and often results in a "dry[] […] of appetite, weight loss Night sweats Bone/joint pain Abdominal discomfort Headaches Shortness of breath Frequent infections Easy bruising or bleeding Petechiae (small red[] marrow aspirate dry tap due to marrow fibrosis increased reticulin CBC anemia thrombocytopenia leukopenia Differential Diagnosis Non-Hodgkin lymphoma Mantle cell lymphoma[]

  • Familial Myelofibrosis

    Usually, only a few cells can be obtained by bone marrow aspiration as it results in a dry tap.[] Hepatosplenomegaly may cause irritability, feeding difficulties, loss of appetite and weight. Children may complain about abdominal pain.[] Pancytopenia and leukoerythroblastosis require further clarification and should prompt a bone marrow biopsy.[]

  • Acute Myelocytic Leukemia

    These blast cells can fill the entire bone marrow and may result in dry tap and myelofibrosis.[] Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[] […] or loss of appetite Frequent infections, because the body’s normal immune system cells are crowded out by cancer cells The signs and symptoms of leukemia are the same as[]

  • Myeloproliferative Disease

    Attempts to perform a bone marrow aspirate and biopsy are often complicated by a dry tap. Special stains of the bone marrow biopsy demonstrate increased fibrosis.[] Signs and Symptoms Patients of myeloproliferative diseases can often experience non-specific symptoms such as fatigue and loss of appetite.[] Symptoms that can be seen in any of these diseases include: fatigue poor appetite ( anorexia ) weight loss night sweats fullness in the stomach after eating only a small amount[]

  • Acute Panmyelosis with Myelofibrosis

    As a consequence of myelofibrosis and dry tap, bone marrow cytology and cytogenetic analyses are only available in a minority of cases.[] Weight loss or loss of appetite. Tests that examine the blood and bone marrow are used to detect (find) and diagnose adult AML.[] Bone marrow aspirate was a dry tap. Bone marrow biopsy showed increased cellularity with panmyelosis [Figure 2].[]

  • Leukemia

    However, this is often associated with a ‘dry tap’ secondary to marked bone marrow fibrosis and a bone marrow trephine may be necessary to confirm ML-DS—it is not clear that[] […] or loss of appetite Enlarged lymph nodes The signs and symptoms of ALL can be the same as more common children’s illnesses and some children are treated for those other illnesses[] Side effects can include hair loss, mouth sores, loss of appetite, nausea and vomiting, diarrhea, increased chance of infections (due to low white blood cell counts), easy[]

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