OBJECTIVES: To observe the five-year efficacy of standardised specific subcutaneous immunotherapy for house dust mite allergy in monosensitised and polysensitised children with persistent allergic rhinitis. METHODS: From January 2007 to August 2009, 236 children with persistent allergic rhinitis were divided into 2[…] [ncbi.nlm.nih.gov]

facial expression 0000338 Leg muscle stiffness 0008969 Lethargy 0001254 Myoclonus 0001336 Oculogyric crisis 0010553 Short attention span Poor attention span Problem paying [rarediseases.info.nih.gov]

0000183 Difficulty walking Difficulty in walking 0002355 Dyskinesia Disorder of involuntary muscle movements 0100660 Fatigue Tired Tiredness [ more ] 0012378 Hypomimic face Dull [rarediseases.info.nih.gov]

† Deceased. From University of Minnesota, Minneapolis VA Health Care System, and HealthPartners, Minneapolis, Minnesota. Disclaimer: Findings and conclusions are those of the authors, who are responsible for its contents; findings and conclusions do not necessarily represent the views of AHRQ. No statement in this[…] [doi.org]

Parkinson's disease type 3 (PD3) is a form of Parkinson's disease that is inherited in an autosomal dominant manner. The underlying mutation has not yet been identified, but PD3 has been related to a 2.5 Mb-locus on the short arm of chromosome 2. To date, PD3 has been diagnosed in distinct families in Europe and[…] [symptoma.com]

We present array comparative genomic hybridization (aCGH) characterization of an unbalanced X-autosome translocation with an Xq interstitial segmental duplication in a 16-year-old girl with primary ovarian failure, mental retardation, attention deficit disorder, learning difficulty and facial dysmorphism. aCGH analysis[…] [ncbi.nlm.nih.gov]

The patient loses facial expression, and an appearance of imbecility is quickly observed. [henriettes-herb.com]

He is stupid, inactive, dull of comprehension, is difficult to interest in the surroundings, or he takes an interest in very childish things. [henriettes-herb.com]

Juvenile Hypothyroidism In Juvenile Hypothyroidism developmental retardation is not as severe as that of cretinism and the symptoms of full-blown adult myxedema are rarely seen. Important features include: Delayed sexual maturation and puberty, as a result the child looks much younger than his age. Eruption of[…] [bestonhealth.com]

OBJECTIVE: The aim of this study is to summarize the experience on prenatal diagnosis of Down syndrome. MATERIALS AND METHODS: The study includes a retrospective data analysis of 157 prenatally detected cases of Down syndrome, routinely diagnosed among 6448 prenatal investigations performed during a 13-year[…] [ncbi.nlm.nih.gov]

Myotonic dystrophy is a kind of multisystem disease, which is inherited in nature. It is a chronic disease condition that gradually progresses, causing muscle wasting, myotonia, heart defects and development of cataracts. Myotonic dystrophy significantly affects multiple organs and systems involving the skeletal[…] [symptoma.com]

Myasthenia gravis Eye deviation and a drooping eyelid in a person with myasthenia gravis trying to open her eyes Specialty Neurology Symptoms Varying degrees muscle weakness, double vision, drooping eyelids, trouble talking, trouble walking[1] Usual onset Women under 40, men over 60[1] Duration Long term[1] Causes[…] [en.wikipedia.org]