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3,119 Possible Causes for Dysarthria, Facial Numbness, Mutation in the Tight Junction Protein 2 Gene

  • Stroke

    A 48-year-old man presented with acute onset of left facial numbness, ataxic gait and double vision.[ncbi.nlm.nih.gov] Dysarthria is more prevalent in left than in right hemisphere lesions.[ncbi.nlm.nih.gov] The symptoms may be mild or dramatic and can mimic a stroke with weakness, numbness, facial droop, and speech difficulties, but these symptoms may only last a few minutes.[medicinenet.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Transient Ischemic Attack

    These symptoms include: Confusion or memory problems Difficulty understanding speech or sudden speech impairment, such as slurred speech Facial paralysis Sudden leg or arm[loyolamedicine.org] A 69-year-old gentleman presented with a TIA episode (dysarthria, right-arm weakness, and numbness).[ncbi.nlm.nih.gov] […] associated with an estimated 9% risk of stroke within 90 days. 1 We report the case of a 72-year-old female who presented with orthostatic symptoms of facial weakness and dysarthria[ncbi.nlm.nih.gov]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Migraine

    A 45-year-old woman with a 20-year history of migrainous headaches presented with complaints of rightsided facial and hand numbness and paraesthesia.[ncbi.nlm.nih.gov] […] middle-aged man presented with intermittent episodes of a brief sensation of explosion in the head, visual flashing, vertigo, hearing loss, tinnitus, confusion, ataxia, dysarthria[ncbi.nlm.nih.gov] Patients may also experience nausea, vomiting, anorexia, neck pain, dizziness, changes in hearing, light sensitivity, difficulty concentrating, facial numbness or weakness[migrainepal.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Primary Progressive Multiple Sclerosis

    Facial numbness and weakness are also common.[medical-dictionary.thefreedictionary.com] A 28-year-old woman developed progressive spastic gait and dysarthria.[ncbi.nlm.nih.gov] Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction[icdlist.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Vertebrobasilar Insufficiency

    Other symptoms include visual defects (diplopia), syncope (drop attacks), dysphagia (difficulty swallowing), dysarthria , hoarseness, and facial numbness, or paresthesias.[encyclopedia.com] Dysarthria, difficulties to swallow, paresthesia and confusion possibly result from VBI.[symptoma.com] Other symptoms include visual defects (diplopia), syncope (drop attacks), dysphagia (difficulty swallowing), dysarthria, hoarseness, and facial numbness, or paresthesias.[encyclopedia.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Basilar Migraine

    The basilar-type aura had a median duration of 60 minutes and comprised vertigo 61%, dysarthria 53%, tinnitus 45%, diplopia 45%, bilateral visual symptoms 40%, bilateral paresthesias[ncbi.nlm.nih.gov] The basilar-type aura comprised diplopia 52%, vertigo 43%, tinnitus 43%, bilateral visual symptoms 39%, hypacusia 26%, ataxia 26%, dysarthria 22%, bilateral paresthesias 13%[ncbi.nlm.nih.gov] Sometimes with either aphasia or dysarthria 5. Aura symptoms almost always develop gradually, or occur in succession, over 5 minutes 6. Aura duration 5-120 minutes 7.[thedailymigraine.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Conversion Disorder

    A' who was experiencing myriad symptoms which included tremors, facial numbness, and severe headaches.[study.com] The symptoms include mild dysarthria to coma or sudden death. The initial subtle clinical presentation could lead to misdiagnosis.[ncbi.nlm.nih.gov] Multiple reports have described patients with disordered articulation and prosody, often following acute aphasia, dysarthria, or apraxia of speech, which results in the perception[ncbi.nlm.nih.gov]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Multiple Sclerosis

    , tingling, or pain: Facial pain Painful muscle spasms Tingling, crawling, or burning feeling in the arms and legs Other brain and nerve symptoms: Decreased attention span[nlm.nih.gov] Articulation abilities were evaluated using the articulation subtest from the Fussi assessment (dysarthria scores).[ncbi.nlm.nih.gov] An 80-year-old man developed dysarthria, quadriplegia, sensory disturbance and ataxia in all limbs.[ncbi.nlm.nih.gov]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Hemiplegia

    The face may be spared during an episode, but weakness of facial muscles (facial paresis) can occur with mouth deviation, slurred speech, and difficulty swallowing.[rarediseases.org] CEREBELLAR LESION Ataxia Nystagmus Dysarthria Intension tremor Hypotonia Dysdiadocokinesis Plantar response – Flexor Paralysis is not a feature of cerebellar disease[slideshare.net] Dysarthria: 2 Severe; patient speech is so slurred as to be unintelligible in the absence of or our of proportion to any dysphagia, or is mute/anarthric 11.[cns.org]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Brain Stem Disorder

    Typical symptoms include eye pain and vision disturbances; speech disorders; facial numbness or pain; incoordination of gait and of the limbs; spasticity, weakness, and increased[britannica.com] A 51-year-old woman with MS developed acute vertigo, ataxia, diplopia, dysarthria, and bifacial weakness.[neurology.org] […] of ipsilateral arm, trunk, or leg: Cuneate and gracile nuclei • Weakness of lower face: Genuflected upper motor neuron fibers to ipsilateral facial nucleus On side opposite[slideshare.net]

    Missing: Mutation in the Tight Junction Protein 2 Gene

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