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19 Possible Causes for Dysarthria, Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs

Did you mean: Dysarthria, Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] He developed dysarthria, difficulty with his gait and dystonia in his arms at the age of 28 years.[ncbi.nlm.nih.gov] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] There was little improvement in the dysarthria or psychiatric symptoms in the first month.[ncbi.nlm.nih.gov] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io]

  • Binswanger Disease

    […] small cerebral arteries Ataxia Autosomal recessive inheritance Babinski sign Dementia Diffuse demyelination of the cerebral white matter Diffuse white matter abnormalities Dysarthria[familydiagnosis.com] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] In addition, affected individuals may have difficulty with speech (dysarthria), swallowing (dysphagia), and urinary bladder control (incontinence).[rarediseases.org]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Abstract Hallervorden and Spatz first described, in a sibship of 12, five sisters with clinically increasing dysarthria and progressive dementia, whose brains showed a brown[ncbi.nlm.nih.gov] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] In our investigation, we describe a patient with progressive neuromuscular issues including dyspnea, dysphagia, dysarthria and progressive ataxia with palatal tremor.[ncbi.nlm.nih.gov] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[ncbi.nlm.nih.gov] The most consistent feature is a dystonic dysarthria.[ncbi.nlm.nih.gov] pallidus, on T2-weighted images.[emedicine.medscape.com]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[pubs.rsna.org] Clinical manifestations of neurologic Wilson's disease include variable combinations of dysarthria, dystonia, tremor, and choreoathetosis.[ncbi.nlm.nih.gov] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1 , 2 ].[omicsonline.org] Lower limb spacity, dysarthria, dysphagia, dystonia, neuropsychiatric symptoms, optic atrophy, Parkinsonism and cognitive decline 1 .[radiopaedia.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[library.med.utah.edu] CASE PRESENTATION: We report a case of 59-year-old Asian woman with blurred vision, dysarthria, myoclonus, and rapidly progressive dementia.[ncbi.nlm.nih.gov] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com] There was dysarthria with nasality of voice. There was generalised hypotonia with power of 5/5 in all limbs.[japi.org]

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