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478 Possible Causes for Dysarthria, Progressive Dysphagia

  • Central Pontine Myelinolysis

    Case Report A 47-year-old man was admitted to the hospital with complaints of progressive dysphagia and dysarthria for a week, and this occurred just 2 days after he stopped[] There was little improvement in the dysarthria or psychiatric symptoms in the first month.[] We describe here a case of CPM that also displayed EPM without hyponatremia after alcohol withdrawal in a chronic alcoholic, and this resulted in a transient progressive course[]

  • Bulbar Poliomyelitis

    Asymmetric flaccid paralysis may develop and progress over 2 to 3 days. Encephalitic signs occasionally predominate.[] […] the respiratory system of the body as a result of which a child affected with Bulbar Polio is likely to experience severe breathing difficulties along with dysphagia and dysarthria[] It can lead to respiratory muscle failure, distress of respiratory control, dysphagia, dysphonia and dysarthria.[]

  • Oculopharyngeal Muscular Dystrophy

    We report a 64 year old Chinese-Malaysian woman who presented with progressive dysphagia and bilateral ptosis for about 6 years.[] Jump to navigation Jump to search Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset progressive myopathy characterized by progressive eyelid ptosis, dysphagia, dysarthria[] dysphagia and bilateral blepharoptosis rather than peripheral muscular weakness.[]

  • Alzheimer Disease

    RESULTS: His syndrome was characterized over the first 6 to 9 years by progressive deterioration of speech production, alteration of mood, and dysphagia but near normal language[] The clinical phenotype was remarkable for spastic dysarthria, limb spasticity, and seizures, in addition to more typical features of EOFAD.[] Abstract A four-generation pedigree exhibiting early-onset autosomal dominant Alzheimer disease (AD) with spastic paraplegia, dystonia, and dysarthria due to a novel 6-nucleotide[]

  • Biotin-Responsive Basal Ganglia Disease

    , and that progresses to severe cogwheel rigidity, dystonia, quadriparesis, and eventual death, if left untreated.[] It is characterized by sub acute encephalopathy with confusion, seizure, dysarthria and dystonia following a history of febrile illness.[] , which progresses to severe rigidity, dystonia, paraplegia and death, if not treated early with biotin.[]

  • Pseudobulbar Palsy

    […] tumors Brain injury Signs and symptoms Pseudobulbar palsy may present with the following signs and symptoms: Difficulty with swallowing (dysphagia) which becomes progressively[] Synonyms: 'bulbar palsy' - lower motor neurone dysarthria, neuromuscular dysarthria, atrophic bulbar paralysis; 'pseudobulbar palsy' - upper motor neurone dysarthria, spastic[] Both bulbar and pseudobulbar palsy are seen mainly in men over 75 years old and present with progressive dysarthria and dysphagia.[]

  • Niemann-Pick Disease Type C

    Swallowing impairment is a frequent cause of morbidity and disability in NPC patients and progressive dysphagia may be considered a marker of neurological progression.[] With the exception of developmental delay/cognitive impairment, these results persisted after 48-96 months in 41 - 55% of the patients (dystonia: 55%, dysarthria: 50%, gait[] Overall, 3/5 patients displayed progressive dysphagia before starting miglustat, and 4/5 showed marked cognitive and/or motor impairment.[]

  • Parkinson's Disease

    Muller J, Wenning GK, Verny M, McKee A, Chaudhuri KR, Jellinger K, Poewe W, Litvan I (2001) Progression of dysarthria and dysphagia in postmortem-confirmed parkinsonian disorders[] Other clinical features include secondary motor symptoms (eg, hypomimia, dysarthria, dysphagia, sialorrhoea, micrographia, shuffling gait, festination, freezing, dystonia,[] Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17:427–442 PubMed CrossRef Google Scholar 6.[]

  • Progressive Bulbar Palsy

    Inclusion Body Myositis Associated with Progressive Dysphagia: Treatment with Cricopharyngeal Myotomy.[] Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles.[] Over time, virtually all patients with progressive bulbar palsy will develop sialorrhea that occurs as a result of severe dysphagia.[]

  • Amyotrophic Lateral Sclerosis

    METHODS: We report the case of a 61-year-old man who presented with progressively worsening limb weakness and dysphagia.[] We examined a 66-year-old Japanese woman manifesting gait disturbance and spastic dysarthria for 6years with positive family history.[] Symptoms include progressive weakness, atrophy, fasciculation, dysphagia, and eventual paralysis of respiratory function.[]

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