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95 Possible Causes for Dyserythropoiesis in Bone Marrow

  • Pyruvate Kinase Deficiency

    We describe dyserythropoiesis in the bone marrow of a child with transfusion dependent anemia and unilateral multicystic dysplastic kidney (MCDK) mimicking Congenital Dyserythropoietic[]

  • Dengue Virus

    […] by bone marrow study.[] The patient recovered with supportive care and the bone marrow pattern was normal on repeated bone marrow study.[] To our knowledge, this is the first reported case of dengue virus-associated hemophagocytosis and dyserythropoiesis in Taiwan.[]

  • Macrocytic Anemia

    The bone marrow biopsy showed a slightly hypercellular bone marrow with normal granulopoiesis, normal megakaryopoiesis and a mild dyserythropoiesis without any ring-sideroblasts[] The in-vitro stem cell culture from the bone marrow revealed an atypical growth of macroclusters, reduced BFU-E and CFU-GEMM colony growth, whereas the CFU-GM colony growth[]

  • Busulfan

    During this period there was marked erythroid hyperplasia in the bone marrow with striking dyserythropoiesis; PAS-positive red cell precursors, as well as moderate numbers[]

  • Congenital Hypoplastic Anemia

    Bone marrow in aplastic anemia 20.[] Investigations to confirm diagnosis  Bone marrow aspiration & trephine biopsy  Hypocellular cell trail ( 25 %)  Replaced by fatty tissue  Containing reticulum cells, lymphocytes[] , plasma cells, and usually tissue mast cells  Megaloblastic changes & other features indicative of dyserythropoiesis 19.[]

  • Systemic Mastocytosis

    A bone marrow biopsy was subsequently performed. Figures Figure 1. Dyserythropoiesis is observed in the bone marrow aspirate smear. Figure 2.[]

  • Congenital Dyserythropoietic Anemia

    […] in the bone marrow.[] On bone marrow examination, approximately 3% of the normoblasts showed changes typical of dyserythropoiesis, including binucleated orthochromatic normoblasts and large trinucleated[] Our patient is a Taiwanese child who presented to us at 8years of age with severe hemolytic anemia, splenomegaly, elevated fetal hemoglobin (HbF), iron overload, and dyserythropoiesis[]

  • Acquired Idiopathic Sideroblastic Anemia

    In 1978, Heimpel [5] claimed that there may be a “pure” form of sideroblastic anemia (PSA) which shows only signs of dyserythropoiesis on bone marrow examination and has a[] (defective developement of eyrocytes) · iron loading bone marrow · haemosiderosis (storage of iron compound – haemosiderin in various places e.g. endocrine, liver , cardiac[] Bone marrow examination showed normal cellularity, myeloid to erythroid ratio (M:E ratio) of 1:1 with normoblastic erythroid maturation [Figure 1] .[]

  • Felty's Syndrome

    At bone marrow examination, normal cellularity with mild dyserythropoiesis was observed. A fiberoptic laryngoscopy showed white plaques on both the true vocal cords.[]

  • Babesiosis

    Bone marrow biopsy was remarkable for dyserythropoiesis, suggesting possible HLH, supported by other blood workup meeting HLH-2004 trial criteria.[]

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