Dyslipidemia: Causes & Reasons

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Possible Causes for Dyslipidemia

Growth Hormone Deficiency

Basic laboratory findings may reveal a reduced GFR, dyslipidemia and impaired glucose levels. [symptoma.com]

Dyslipidemia and hyperuricemia were the most common metabolic disturbances in Chinese patients. [ncbi.nlm.nih.gov]

[…] growth hormones in the adults, which is associated with increased clustering of conventional cardiovascular risk factors such as central obesity, insulin resistance and dyslipidemia [ncbi.nlm.nih.gov]

Metabolic Syndrome

Our study showed significantly high prevalence of raised blood pressure, hyperglycemia and dyslipidemia in Ethiopia. [ncbi.nlm.nih.gov]

The major components of metabolic syndrome x include excess abdominal fat; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state [icd9data.com]

Insulin resistance, visceral adiposity, atherogenic dyslipidemia, endothelial dysfunction, genetic susceptibility, elevated blood pressure, hypercoagulable state, and chronic [ncbi.nlm.nih.gov]

Hypercholesterolemia

dyslipidemia in children and adolescents. [doi.org]

Most adult cases of dyslipidemia are due to a combination of the effects of polygenes and unhealthy lifestyle. [online.epocrates.com]

Guidelines recommend statins as first-line therapy for dyslipidemia. [ncbi.nlm.nih.gov]

Hyperuricemia

[…] hyperuricemia on dyslipidemia in women or DM both in men and in women is either linked with other risk factors (eg, dyslipidemia) or is weak or absent (DM). [ahajournals.org]

The mean uric acid levels were higher in women (P < .001) in the condition of dyslipidemia (P = .026), β-blocker usage (P = .002), and thiazide diuretics (P = .020). [ncbi.nlm.nih.gov]

There was no difference in age at onset, sex, BMI and incidence of diabetes mellitus, hypertension or dyslipidemia. [ncbi.nlm.nih.gov]

Heterozygous Familial Hypercholesterolemia

About HeFH Heterozygous familial hypercholesterolemia (HeFH), and a much rarer form called homozygous familial hypercholesterolemia (HoFH), are severe genetic dyslipidemias [globenewswire.com]

Laboratories International: Heterozygous Familial Hypercholesterolemia (HeFH) Additional relevant MeSH terms: Hypercholesterolemia Hyperlipoproteinemia Type II Hyperlipidemias Dyslipidemias [clinicaltrials.gov]

Topics: Dyslipidemia [thecardiologyadvisor.com]

Familial Hypercholesterolemia Type 1

Dyslipidemia is tightly linked to, although not causative of, diseases such as obesity and type 2 diabetes. [doi.org]

Abstract Familial hypercholesterolemia (FH) is the most common inherited form of dyslipidemia and a major cause of premature cardiovascular disease. [ncbi.nlm.nih.gov]

Patients younger than 18 years of age or with secondary causes of dyslipidemia were excluded (n=98). [ncbi.nlm.nih.gov]

Insulin Resistance

Lipodystrophic syndromes are uncommon medical conditions which are normally associated with metabolic disorders, such as diabetes mellitus, dyslipidemia, and fatty liver disease [ncbi.nlm.nih.gov]

Fructose-induced insulin resistant states are commonly characterized by a profound metabolic dyslipidemia, which appears to result from hepatic and intestinal overproduction [ncbi.nlm.nih.gov]

BACKGROUND: The emergence of diseases such as dyslipidemia, systemic arterial hypertension, insulin resistance and metabolic syndrome in children and adolescents has brought [ncbi.nlm.nih.gov]

Hyperlipidemia

[…] w diabetic hyperlipidemia DM 2 W diabetic dyslipidemia DM 2 w diabetic hyperlipidemia Dyslipidemia Dyslipidemia (high blood cholesterol/triglycerides Dyslipidemia (high blood [icd9data.com]

dyslipidemia in children and adolescents. [doi.org]

[…] cholesterol/triglycerides) Dyslipidemia associated with Type 2 diabetes mellitus Dyslipidemia due to type 1 diabetes mellitus Dyslipidemia with high density lipoprotein below [icd9data.com]

Diabetes Mellitus Type 2

Statins are the best treatment for diabetic dyslipidemia, with little benefit from adding a fibrate. [ncbi.nlm.nih.gov]

[…] diabetes have examined the effects of intensive glycemic control on cardiovascular outcomes, and treatment of common concomitant risk factors, in particular hypertension and dyslipidemia [ncbi.nlm.nih.gov]

Combined Hyperlipidemia

It is hereditary and characterized by dyslipidemia in multiple members of the same family. [symptoma.com]

Familial Hypercholesterolemia

Abstract Familial hypercholesterolemia (FH) is the most common inherited form of dyslipidemia and a major cause of premature cardiovascular disease. [ncbi.nlm.nih.gov]

Patients younger than 18 years of age or with secondary causes of dyslipidemia were excluded (n=98). [ncbi.nlm.nih.gov]

However, based on his advanced atherosclerosis, we cannot exclude the possibility that our patient may be accompanying dyslipidemia due to causes in addition to heterozygous [ncbi.nlm.nih.gov]

Cholesterol Ester Storage Disease

Blood analysis typically reveals abnormal liver function tests with coincident dyslipidemia. [ncbi.nlm.nih.gov]

Robert_block@urmc.rochester.edu Cholesterol ester storage disease is an exceptionally rare dyslipidemia with less than 150 cases reported in the medical literature. [europeanreview.org]

The percentage of our patients presenting with dyslipidemia (100%) was higher than in the series of 135 patients reviewed by Bernstein et al (87%) (10). [journals.lww.com]

Polycystic Ovary Syndrome

Women with PCOS are affected by a variety of metabolic disorders, including insulin resistance, metabolic syndrome, type-2 diabetes, dyslipidemia and obesity. [ncbi.nlm.nih.gov]

clinicians should document individual risk factors including age, smoking, obesity, any degree of glucose intolerance including prediabetes and diabetes, hypertension, dyslipidemia [ncbi.nlm.nih.gov]

Metabolic Disease

We also explore how dysregulation of autophagy leads to cell death in models of metabolic disease and its contributing factors-including nutrient state, hyperglycemia, dyslipidemia [ncbi.nlm.nih.gov]

KEYWORDS: Autophagy; Cellular metabolism; Diabetes; Dyslipidemia; T cells; Therapeutics [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

– triglycerides >150 mg/dL >150 mg/dL >150 mg/dL >150 mg/dL or patient taking specific treatment for hypertriglyceridemia Dyslipidemia – HDL-C Hypertension >140/90 mmHg or [arupconsult.com]

Hypertriglyceridemia

Together, these 2 dyslipidemias account for 85% of familial dyslipidemias. Table 2. [jabfm.org]

Dyslipidemia is the most common lipid metabolism disorder in humans, and its etiology remains elusive. [ncbi.nlm.nih.gov]

[…] these dyslipidemias except Fredrickson type IIa (familial hypercholesterolemia). [jabfm.org]

Familial Partial Lipodystrophy

FPLD 2 should be considered in the differential diagnosis of diabetes, dyslipidemia, steatohepatitis, acanthosis nigricans and polycystic ovary syndrome. [ncbi.nlm.nih.gov]

Dyslipidemia was present in 13 family members. [ncbi.nlm.nih.gov]

FPLD recapitulates the main metabolic attributes of the insulin resistance syndrome, including central obesity, hyperinsulinemia, glucose intolerance and diabetes, dyslipidemia [ncbi.nlm.nih.gov]

Familial Combined Hyperlipidemia

PURPOSE OF REVIEW: To provide an overview of recent advances that have defined the first putative genes behind familial combined hyperlipidemia, the most common genetic dyslipidemia [ncbi.nlm.nih.gov]

Adipocyte fatty acid-binding protein 4 (FABP4) appears to be a determinant of atherogenic dyslipidemia. [ncbi.nlm.nih.gov]

Article Metrics Metrics To provide an overview of recent advances that have defined the first putative genes behind familial combined hyperlipidemia, the most common genetic dyslipidemia [journals.lww.com]

Lipodystrophy

although 18/23 had dyslipidemia and 12/23 had diabetes mellitus. [circ.ahajournals.org]

Laboratory tests revealed mild dyslipidemia, and low serum levels of complement-component 3. [ncbi.nlm.nih.gov]

[…] a group of rare disorders characterized by deficiency of adipose tissue resulting in hypoleptinemia, and metabolic abnormalities including insulin resistance, diabetes, dyslipidemia [ncbi.nlm.nih.gov]

Acquired Partial Lipodystrophy

[…] review of the data of patients with ALD after HSCT revealed common clinical features, including aberrant fat distribution, impaired glucose tolerance (IGT) or diabetes and dyslipidemia [keio.pure.elsevier.com]

Both patients had distinct partial lipodystrophy at the hips and distal extremities with severe hypertension, insulin resistance, dyslipidemia, and steatohepatitis. [endocrine-abstracts.org]

Laboratory tests revealed mild dyslipidemia, and low serum levels of complement-component 3. [ncbi.nlm.nih.gov]

Familial Hypercholesterolemia Type 2

American Academy of Clinical Endocrinology for prevention and management of many endocrine disorders including diabetes, growth hormone deficiency, dysmetabolic syndrome, dyslipidemia [books.google.com]

[…] or Positive family history of dyslipidemia or Positive family history of dyslipidemia or Positive family history of dyslipidemia or Unknown family history and other CHD risk [accesspediatrics.mhmedical.com]

[…] of the dyslipidemia observed in patients with diabetes. [care.diabetesjournals.org]

Acquired Generalized Lipodystrophy

Leptin deficiency is associated with a severe form of the metabolic syndrome characterized by dyslipidemia, insulin resistance, diabetes, and ovarian dysfunction. [ncbi.nlm.nih.gov]

This condition is characterized by severe dyslipidemia, insulin resistance, diabetes mellitus, and steatohepatitis. [ncbi.nlm.nih.gov]

AGL are complicated by severe insulin resistance, diabetes mellitus, dyslipidemia and fatty liver. In most patients evidence exists of an autoimmune etiology. [endocrine-abstracts.org]

Familial Hyperlipidemia

However, when comparing FCH patients with and without AMI, we found significant differences ( P In conclusion, FCH is a primary dyslipidemia frequently associated with IR [revespcardiol.org]

Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease! [amboss.com]

Cholesterol-Ester Transfer Protein Deficiency

Rare hyperlipidemia Rare hypolipidemia Rare syndromic dyslipidemia Sitosterolemia Tangier disease Wolman disease [se-atlas.de]

[…] of the dyslipidemia observed in patients with diabetes. [care.diabetesjournals.org]

"The role of CETP inhibition in dyslipidemia". Current Atherosclerosis Reports. 9 (2): 125–33. doi : 10.1007/s11883-007-0008-5. [en.wikipedia.org]

Hyperlipoproteinemia

The prevention of apoE4[R142C]-induced dyslipidemia by deletion of the 203-299 residues suggests that, in the full-length protein, the R142C substitution may have altered [ncbi.nlm.nih.gov]

He subsequently developed refractory dyslipidemia, palmar crease, and tuberous xanthomas. [ncbi.nlm.nih.gov]

Congenital Generalized Lipodystrophy

[…] the best care and new opportunities for patients with dyslipidemias. [books.google.com]

[…] features of CGL such as generalized loss of subcutaneous fat from birth, acanthosis nigricans, acromegaloid habitus, umbilical prominence, hepatosplenomegaly, hypoleptinemia, dyslipidemia [ncbi.nlm.nih.gov]

Leptin deficiency is associated with a severe form of the metabolic syndrome characterized by dyslipidemia, insulin resistance, diabetes, and ovarian dysfunction. [ncbi.nlm.nih.gov]

Disorder of Lipid Metabolism

Ito, Pharm.D., FCCP, FNLA, CLS. 17 Obesity and Dyslipidemia Kenneth Feingold, MD and Carl Grunfeld, MD, PhD 18 Management of Dyslipidemia in the Elderly Dan Streja, MD, FRCPC [endotext.org]

[…] on Lipid Profiles in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/Ritonavir Completed NCT02442700 Phase 4 pitavastatin;placebo 49 The Impact of Ezetimibe [malacards.org]

Jacobson TA, Ito MK, Maki KC, et al: National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1-executive summary. [mayomedicallaboratories.com]

Mauriac Syndrome

The male patient presented puberty delay and dyslipidemia. [elsevier.es]

Mauriac's syndrome is a rare disease, which includes short stature, growth maturation delay, dyslipidemia, moon facies, protuberant abdomen, hepatomegaly with transaminase [ncbi.nlm.nih.gov]

None of the patients presented short stature and 5 of them presented mixed dyslipidemia. [elsevier.es]

Hyperlipoproteinemia Type 5

Hyperlipidemia, which refers to an increase in cholesterol, triglyceride (TG), or both, is the most common form of dyslipidemia. [genome.jp]

Also,the identification of other primary relatives with dyslipidemias is useful in making the diagnosis. [wikidoc.org]

Homozygous Familial Hypercholesterolemia

In clinical studies of patients with mixed dyslipidemia, MBX-8025 has been shown to reduce LDL-C. [ir.cymabay.com]

METHODS AND RESULTS: Data were collected from the Spanish Dyslipidemia Registry of the Spanish Atherosclerosis Society and from all molecular diagnoses performed for familial [ncbi.nlm.nih.gov]

National Lipid Association hosted entitled "Managing the Challenging Homozygous Familial Hypercholesterolemia Patient-Academic Insights and Practical Approaches for a Severe Dyslipidemia [ncbi.nlm.nih.gov]

Hyperlipoproteinemia Type 4

In Fredrickson Type III dyslipidemia, the elevated triglyceride is usually associated with higher levels of cholesterol. [blogs.webmd.com]

It is a mixture of types I and IV familial dyslipidemias. Lab findings: TG levels are high, whereas cholesterol concentration increases only moderately. [medicowesome.com]