Dyslipidemia: Causes & Reasons

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Possible Causes for Dyslipidemia

Growth Hormone Deficiency

Basic laboratory findings may reveal a reduced GFR, dyslipidemia and impaired glucose levels. [symptoma.com]

Dyslipidemia and hyperuricemia were the most common metabolic disturbances in Chinese patients. [ncbi.nlm.nih.gov]

[…] growth hormones in the adults, which is associated with increased clustering of conventional cardiovascular risk factors such as central obesity, insulin resistance and dyslipidemia [ncbi.nlm.nih.gov]

Metabolic Syndrome

Our study showed significantly high prevalence of raised blood pressure, hyperglycemia and dyslipidemia in Ethiopia. [ncbi.nlm.nih.gov]

[…] extensive information is available for diuretics or beta -blockers in hypertension, hepatic hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) in dyslipidemia [liebertonline.com]

The major components of metabolic syndrome x include excess abdominal fat; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state [icd9data.com]

Hypercholesterolemia

Keywords: Dyslipidemia, Guidelines, Cardiovascular diseases Core tip: Guidelines for dyslipidemia management have been developed by independent organizations internationally [ncbi.nlm.nih.gov]

July 2015. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening [uspreventiveservicestaskforce.org]

dyslipidemia in children and adolescents. [doi.org]

Familial Hypercholesterolemia Type 1

Dyslipidemias may be Primary: Genetic Secondary: Caused by lifestyle and other factors Both primary and secondary causes contribute to dyslipidemias in varying degrees. [merckmanuals.com]

Dyslipidemias have been traditionally classified in accordance with the elevated lipoprotein classes ( Table 2 ). 14 Currently, genetic dyslipidemias are classified as familial [aafp.org]

Dyslipidemia is tightly linked to, although not causative of, diseases such as obesity and type 2 diabetes. [doi.org]

Heterozygous Familial Hypercholesterolemia

About HeFH Heterozygous familial hypercholesterolemia (HeFH), and a much rarer form called homozygous familial hypercholesterolemia (HoFH), are severe genetic dyslipidemias [globenewswire.com]

Laboratories International: Heterozygous Familial Hypercholesterolemia (HeFH) Additional relevant MeSH terms: Hypercholesterolemia Hyperlipoproteinemia Type II Hyperlipidemias Dyslipidemias [clinicaltrials.gov]

Topics: Dyslipidemia [thecardiologyadvisor.com]

Hyperlipidemia

Risk factors for CVD in the adult (obesity, hypertension, dyslipidemia, and smoking) accelerate the atherosclerotic process in childhood. [utmb.edu]

[…] w diabetic hyperlipidemia DM 2 W diabetic dyslipidemia DM 2 w diabetic hyperlipidemia Dyslipidemia Dyslipidemia (high blood cholesterol/triglycerides Dyslipidemia (high blood [icd9data.com]

Dyslipidemias may be Primary: Genetic Secondary: Caused by lifestyle and other factors Both primary and secondary causes contribute to dyslipidemias in varying degrees. [merckmanuals.com]

Combined Hyperlipidemia

Nearly 90% of patients with CHD have some form of dyslipidemia. [unboundmedicine.com]

It is hereditary and characterized by dyslipidemia in multiple members of the same family. [symptoma.com]

Cholesterol Ester Storage Disease

Blood analysis typically reveals abnormal liver function tests with coincident dyslipidemia. [ncbi.nlm.nih.gov]

Robert_block@urmc.rochester.edu Cholesterol ester storage disease is an exceptionally rare dyslipidemia with less than 150 cases reported in the medical literature. [europeanreview.org]

CESD patients present in childhood with hepatomegaly and dyslipidemia characterized by elevated total and low-density lipoprotein cholesterol (LDL-C), with elevated triglycerides [ncbi.nlm.nih.gov]

Hypertriglyceridemia

Be sure to read Dyslipidemia In Insulin Resistance: Hypertriglyceridemia And Low HDL Cholesterol Dyslipidemia In Insulin Resistance: Hypertriglyceridemia And Low HDL Cholesterol [diabetesincontrol.com]

Together, these 2 dyslipidemias account for 85% of familial dyslipidemias. Table 2. [jabfm.org]

In summary, beware of hypertriglyceridemia and low HDL-C, the duo of dyslipidemia commonly found in insulin resistance. [diabetesincontrol.com]

Familial Partial Lipodystrophy

[…] the best care and new opportunities for patients with dyslipidemias. [books.google.com]

FPLD 2 should be considered in the differential diagnosis of diabetes, dyslipidemia, steatohepatitis, acanthosis nigricans and polycystic ovary syndrome. [ncbi.nlm.nih.gov]

Dyslipidemia was present in 13 family members. [ncbi.nlm.nih.gov]

Familial Combined Hyperlipidemia

Nearly 90% of patients with CHD have some form of dyslipidemia. [unboundmedicine.com]

Clinical dyslipoproteinemias Most dyslipidemias are multifactorial in etiology and reflect the effects of genetic influences coupled with diet, inactivity, smoking, alcohol [unboundmedicine.com]

PURPOSE OF REVIEW: To provide an overview of recent advances that have defined the first putative genes behind familial combined hyperlipidemia, the most common genetic dyslipidemia [ncbi.nlm.nih.gov]

Familial Hypercholesterolemia Type 2

Consequently, there are no numeric definitions of dyslipidemia; the term is applied to lipid levels for which treatment has proven beneficial. [merckmanuals.com]

American Academy of Clinical Endocrinology for prevention and management of many endocrine disorders including diabetes, growth hormone deficiency, dysmetabolic syndrome, dyslipidemia [books.google.com]

[…] or Positive family history of dyslipidemia or Positive family history of dyslipidemia or Positive family history of dyslipidemia or Unknown family history and other CHD risk [accesspediatrics.mhmedical.com]

Lipodystrophy

although 18/23 had dyslipidemia and 12/23 had diabetes mellitus. [circ.ahajournals.org]

Laboratory tests revealed mild dyslipidemia, and low serum levels of complement-component 3. [ncbi.nlm.nih.gov]

[…] a group of rare disorders characterized by deficiency of adipose tissue resulting in hypoleptinemia, and metabolic abnormalities including insulin resistance, diabetes, dyslipidemia [ncbi.nlm.nih.gov]

Familial Hyperlipidemia

However, when comparing FCH patients with and without AMI, we found significant differences ( P In conclusion, FCH is a primary dyslipidemia frequently associated with IR [revespcardiol.org]

Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease! [amboss.com]

Acquired Partial Lipodystrophy

[…] review of the data of patients with ALD after HSCT revealed common clinical features, including aberrant fat distribution, impaired glucose tolerance (IGT) or diabetes and dyslipidemia [keio.pure.elsevier.com]

Both patients had distinct partial lipodystrophy at the hips and distal extremities with severe hypertension, insulin resistance, dyslipidemia, and steatohepatitis. [endocrine-abstracts.org]

Laboratory tests revealed mild dyslipidemia, and low serum levels of complement-component 3. [ncbi.nlm.nih.gov]

Familial Hypercholesterolemia

Abstract Familial hypercholesterolemia (FH) is the most common inherited form of dyslipidemia and a major cause of premature cardiovascular disease. [ncbi.nlm.nih.gov]

Patients younger than 18 years of age or with secondary causes of dyslipidemia were excluded (n=98). [ncbi.nlm.nih.gov]

However, based on his advanced atherosclerosis, we cannot exclude the possibility that our patient may be accompanying dyslipidemia due to causes in addition to heterozygous [ncbi.nlm.nih.gov]

Disorder of Lipid Metabolism

Ito, Pharm.D., FCCP, FNLA, CLS. 17 Obesity and Dyslipidemia Kenneth Feingold, MD and Carl Grunfeld, MD, PhD 18 Management of Dyslipidemia in the Elderly Dan Streja, MD, FRCPC [endotext.org]

[…] on Lipid Profiles in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/Ritonavir Completed NCT02442700 Phase 4 pitavastatin;placebo 49 The Impact of Ezetimibe [malacards.org]

Jacobson TA, Ito MK, Maki KC, et al: National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1-executive summary. [mayomedicallaboratories.com]

Hyperlipoproteinemia Type 5

Hyperlipidemia, which refers to an increase in cholesterol, triglyceride (TG), or both, is the most common form of dyslipidemia. [genome.jp]

Also,the identification of other primary relatives with dyslipidemias is useful in making the diagnosis. [wikidoc.org]

Hyperlipoproteinemia Type 4

In Fredrickson Type III dyslipidemia, the elevated triglyceride is usually associated with higher levels of cholesterol. [blogs.webmd.com]

It is a mixture of types I and IV familial dyslipidemias. Lab findings: TG levels are high, whereas cholesterol concentration increases only moderately. [medicowesome.com]

Hyperlipoproteinemia

Hyperlipoproteinemia (HLP) and dyslipidemia (DLP) are of course mainly perceived as diseases of common incidence and are typically seen as the greatest risk factors (RF) in [pesquisa.bvsalud.org]

The prevention of apoE4[R142C]-induced dyslipidemia by deletion of the 203-299 residues suggests that, in the full-length protein, the R142C substitution may have altered [ncbi.nlm.nih.gov]

He subsequently developed refractory dyslipidemia, palmar crease, and tuberous xanthomas. [ncbi.nlm.nih.gov]

Congenital Generalized Lipodystrophy

[…] the best care and new opportunities for patients with dyslipidemias. [books.google.com]

[…] features of CGL such as generalized loss of subcutaneous fat from birth, acanthosis nigricans, acromegaloid habitus, umbilical prominence, hepatosplenomegaly, hypoleptinemia, dyslipidemia [ncbi.nlm.nih.gov]

Leptin deficiency is associated with a severe form of the metabolic syndrome characterized by dyslipidemia, insulin resistance, diabetes, and ovarian dysfunction. [ncbi.nlm.nih.gov]

Hyperlipoproteinemia Type 1

Published on Oct 15, 2018 Familial hyperchylomicronemia, also called type I dyslipidemia, is a rare, genetic disease characterized by the build-up of chylomicrons that carry [youtube.com]

DYSLIPIDEMIA Dyslipidemia is having an abnormal amount of lipids or fats in the blood. [specialty.mims.com]

Cholesterol-Ester Transfer Protein Deficiency

Rare hyperlipidemia Rare hypolipidemia Rare syndromic dyslipidemia Sitosterolemia Tangier disease Wolman disease [se-atlas.de]

[…] of the dyslipidemia observed in patients with diabetes. [care.diabetesjournals.org]

"The role of CETP inhibition in dyslipidemia". Current Atherosclerosis Reports. 9 (2): 125–33. doi : 10.1007/s11883-007-0008-5. [en.wikipedia.org]

Hypoalphalipoproteinemia

3215 Genetic determinants of dyslipidemia in populations 206 322 The candidate gene approach in experimental models of dyslipidemia 209 3222 In vivo studies and animal models [books.google.com]

A total number of 1420 dyslipidemia patients (mean age 50 years, male 58%) were included and analyzed in this report. [mji.ui.ac.id]

Abstract Clinical management of dyslipidemias has focused primarily on the low-density lipoprotein cholesterol (LDL-C) fraction; however, lipid disorders accompanied by low [ncbi.nlm.nih.gov]

Acquired Generalized Lipodystrophy

Leptin deficiency is associated with a severe form of the metabolic syndrome characterized by dyslipidemia, insulin resistance, diabetes, and ovarian dysfunction. [ncbi.nlm.nih.gov]

This condition is characterized by severe dyslipidemia, insulin resistance, diabetes mellitus, and steatohepatitis. [ncbi.nlm.nih.gov]

AGL are complicated by severe insulin resistance, diabetes mellitus, dyslipidemia and fatty liver. In most patients evidence exists of an autoimmune etiology. [endocrine-abstracts.org]

Chylomicronemia Syndrome

Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, high LDL-c or low HDL-c), correlate with a significant [semanticscholar.org]

Dyslipidemia genetics The association between family history of dyslipidemia and the risk of CVD is supported by a large body of evidence 18 – 22. [f1000research.com]

There was only family history of dyslipidemia. The patient's father and brother both were diagnosed with hyperlipidemia. [omicsonline.org]

Insulin Resistance

Fructose-induced insulin resistant states are commonly characterized by a profound metabolic dyslipidemia, which appears to result from hepatic and intestinal overproduction [ncbi.nlm.nih.gov]

BACKGROUND: The emergence of diseases such as dyslipidemia, systemic arterial hypertension, insulin resistance and metabolic syndrome in children and adolescents has brought [ncbi.nlm.nih.gov]

Lipodystrophic syndromes are uncommon medical conditions which are normally associated with metabolic disorders, such as diabetes mellitus, dyslipidemia, and fatty liver disease [ncbi.nlm.nih.gov]

Metabolic Disease

We also explore how dysregulation of autophagy leads to cell death in models of metabolic disease and its contributing factors-including nutrient state, hyperglycemia, dyslipidemia [ncbi.nlm.nih.gov]

KEYWORDS: Autophagy; Cellular metabolism; Diabetes; Dyslipidemia; T cells; Therapeutics [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

– triglycerides >150 mg/dL >150 mg/dL >150 mg/dL >150 mg/dL or patient taking specific treatment for hypertriglyceridemia Dyslipidemia – HDL-C Hypertension >140/90 mmHg or [arupconsult.com]

Hyperlipoproteinemia Type 1C

This article originally appeared on MPR Topics: Cholesterol Dyslipidemia [thecardiologyadvisor.com]

Yes Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Hyperlipoproteinemias Hyperlipidemias Hyperlipoproteinemia Type I Disease Pathologic Processes Dyslipidemias [clinicaltrials.gov]

Managing dyslipidemia in chronic kidney disease. J Am Coll Cardiol. 2008 Jun 24. 51(25):2375-84. [Medline]. [medscape.com]

Hyperuricemia

[…] hyperuricemia on dyslipidemia in women or DM both in men and in women is either linked with other risk factors (eg, dyslipidemia) or is weak or absent (DM). [ahajournals.org]

The mean uric acid levels were higher in women (P < .001) in the condition of dyslipidemia (P = .026), β-blocker usage (P = .002), and thiazide diuretics (P = .020). [ncbi.nlm.nih.gov]

There was no difference in age at onset, sex, BMI and incidence of diabetes mellitus, hypertension or dyslipidemia. [ncbi.nlm.nih.gov]