Dysmetria: Causes & Reasons

Possible Causes for Dysmetria

Damage to the cerebellum can lead to: 1) loss of coordination of motor movement (asynergia), 2) the inability to judge distance and when to stop (dysmetria), 3) the inability [neuroskills.com]

Andreason suggests the presence of cognitive dysmetria due to cerebellar involvement in schizophrenia which is analogous to motor dysmetria so far described in cerebellar [ijpm.info]

Dysmetria and ataxia were most resistant to rehabilitation. [cerebellumandataxias.biomedcentral.com]

Autosomal Recessive Spinocerebellar Ataxia 8

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

They may also have difficulty with movements that involve judging distance or scale (dysmetria). [ghr.nlm.nih.gov]

Adult-Onset Autosomal Recessive Cerebellar Ataxia

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

A slowly progressive cerebellar syndrome with various combinations of oculomotor disorders, dysarthria, dysmetria/kinetic tremor, and ataxic gait are key presenting features [emedicine.medscape.com]

Autosomal Recessive Spinocerebellar Ataxia Type 17

SCAR17 features include non-progressive congenital cerebellar ataxia, mildly delayed walking with an unsteady gait and frequent falls, dysarthria, dysmetria, hypotonia in [malacards.org]

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [ipfs.io]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

Autosomal Recessive Spinocerebellar Ataxia

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

They may also have difficulty with movements that involve judging distance or scale (dysmetria). [ghr.nlm.nih.gov]

Autosomal Recessive Spinocerebellar Ataxia 18

Phenotypic manifestations commonly consist of cerebellar dysarthria, gait ataxia, and dysmetria. [karger.com]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

[…] decreased in the lower limbs, his deep tendon reflexes were hyporeflexic in all the limbs, Babinski signs were absent bilaterally, and he had bilateral upper and lower limb dysmetria [synapse.koreamed.org]

Spinocerebellar Ataxia Type 12

Abstract SCA12 is an autosomal dominant cerebellar ataxia characterized by onset in the fourth decade of life with action tremor of arms and head, mild ataxia, dysmetria, [ncbi.nlm.nih.gov]

[…] is a progressive autosomal-dominant disorder, caused by a CAG/CTG repeat expansion in PPP2R2B on chromosome 5q32, and characterized by tremor, gait ataxia, hyperreflexia, dysmetria [ncbi.nlm.nih.gov]

[…] consent has been received Technical Information Clinical Significance: Detect repeat expansions in SCA12 gene Typical Presentation: Tremor of arms and head, mild ataxia, dysmetria [athenadiagnostics.com]

Autosomal Recessive Spastic Ataxia with Leukoencephalopathy

Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. [uniprot.org]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

[…] cerebellar hemisphere) Neocerebellum Connected with Pons and cortex through thalalmus Planning and initiation of movements Regulation of fine limb movements Limb ataxia: Dysmetria [slideshare.net]

Lateral Medullary Syndrome

Half of the patients had permanent saccadic dysmetria. [ncbi.nlm.nih.gov]

There are strong influences of both gaze and gravity, but relatively little limb dysmetria. References Caplan LR. Vertebrobasilar disease. [dizziness-and-balance.com]

Signs- Cerebellar Ataxic/ Drunken Gait Dysdiadochokinesia ( unable to perform quick alternative repeated actions like pronation/supination) Pendular knee jerk Nystagmus Dysmetria [medchrome.com]

Infantile-Onset Autosomal Recessive Non-Progressive Cerebellar Ataxia

Language development deficit Late-onset speech development Poor language development Speech and language delay Speech and language difficulties Speech delay [ more ] 0000750 Dysmetria [rarediseases.info.nih.gov]

In addition to these eye movement abnormalities, patients had developmental delays and ataxia, nystagmus, dysarthria, tremor, dysmetria, and seizures The epilepsies. [epilepsygenetics.net]

Spinocerebellar Ataxia Type 10

Clinical features include dysmetria of limbs, gait ataxia, dysarthria and gaze evoked nystagmus with fragmented pursuit. [annalsofian.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

On examination, she had horizontal and vertical nystagmus, fragmented ocular pursuit, ocular dysmetria, scanning speech, mild limb and gait ataxia with a widened base, slow [ng.neurology.org]

Spinocerebellar Ataxia Type 5

Examination was noteworthy for mild dysarthria, slowing of saccades and gaze-holding difficulty, diffuse hyporeflexia, mild dysmetria and dysdiadochokinesis, and gait ataxia [jamanetwork.com]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

abnormal ramp tracking in the upper limbs, and dyssynergia and dysmetria in the lower limbs. [jnnp.bmj.com]

Cerebellar Neoplasm

Tumors of the cerebellum Supplemental material : Video of saccadic dysmetria (same patient as above). [dizziness-and-balance.com]

Lesions involving the cerebellar hemispheres are more likely to show limb ataxias and associated dysmetria. [clinicalgate.com]

[…] quadrantanopia, behavioral alterations Occipital lobe Contralateral hemianopia Thalamus Contralateral sensory loss, behavioral changes, language disorder Cerebellum Ataxia, dysmetria [aafp.org]

Friedreich Ataxia

We describe two sisters with early onset gait ataxia, rapid disease progression, absent or very mild dysarthria and upper limb dysmetria, retained knee jerks in one, slight [ncbi.nlm.nih.gov]

Friedreich Ataxia (FA) is a neurodegenerative disorder characterised by progressive gait disturbance, dysarthria, dysmetria and other coordination disorders. [ncbi.nlm.nih.gov]

Clinical features Neurological Progressive ataxia (muscle weakness and impaired coordination) of all limbs Bilateral lower limbs equally affected Wide-based steppage gait with dysmetria [amboss.com]

Spinocerebellar Ataxia Type 1

Abnormality of this is called dysmetria. [stanfordmedicine25.stanford.edu]

DTRs can be exaggerated, and dysmetria is common. The mean age of onset is about age 40. Some cognitive decline may occur. [disorders.eyes.arizona.edu]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Autosomal Recessive Spastic Paraplegia Type 20

Childhood onset Symptoms begin in childhood 0011463 Difficulty walking Difficulty in walking 0002355 Drooling Dribbling 0002307 Dysarthria Difficulty articulating speech 0001260 Dysmetria [rarediseases.info.nih.gov]

The role of the cerebellum in cognition and emotion: personal reflections since 1982 on the dysmetria of thought hypothesis, and its historical evolution from theory to therapy [elsevier.es]

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

Autosomal Recessive Spastic Paraplegia Type 26

[…] reported manifestations include skeletal abnormalities (i.e. pes cavus, scoliosis ), dyskinesia, dystonia, cataracts, cerebellar signs (i.e. saccadic dysfunction, nystagmus, dysmetria [rarediseases.info.nih.gov]

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Dysequilibrium Syndrome

[…] difficulties Speech delay [ more ] 0000750 Dysarthria Difficulty articulating speech 0001260 Dysdiadochokinesis Difficulty performing quick and alternating movements 0002075 Dysmetria [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 44

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Spinocerebellar Ataxia Type 14

abnormal ramp tracking in the upper limbs, and dyssynergia and dysmetria in the lower limbs. [jnnp.bmj.com]

FGF14 13q34 SCA35 40-48 years Unknown gait and limb ataxia, dysarthria, ocular dysmetria, intention tremor, pseudobulbar palsy, spasmodic torticollis, extensor plantar responses [en.wikipedia.org]

During the last two decades there has been a growing interest for the cerebellum’s role also in non-motor functions, with the introduction of the “dysmetria of thought”-hypothesis [bmcneurol.biomedcentral.com]

Autosomal Recessive Spastic Paraplegia Type 35

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

Eye movements show horizontal bidirectional nystagmus, saccadic alterations of smooth ocular pursuit and saccadic dysmetria. 18 Supranuclear gaze palsy has been described [acnr.co.uk]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Niemann-Pick Disease Type C

Neurological examination revealed a broad-based ataxic gait, limb dysmetria, downward vertical gaze palsy, brisk lower limb reflexes and ankle clonus, while neuropsychological [ncbi.nlm.nih.gov]

We clinically evaluated patients' neurological involvement, giving a score of severity ranging from 0 (best) to 3 (worst) for gait abnormalities, dystonia, dysmetria, dysarthria [ncbi.nlm.nih.gov]

Typical neurological manifestations include vertical supranuclear gaze palsy, saccadic eye movement abnormalities, cerebellar ataxia, dystonia, dysmetria, dysphagia and dysarthria [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 49

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Cerebellar Disease

The graphs in this article illustrate ocular flutter, dysmetria, abnormal (nonsmooth) pursuit, instability of fixation, faulty vestibular suppression, impaired optokinetic [ncbi.nlm.nih.gov]

(From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141) Cerebellar Ataxia Adiadochokinesis | Ataxia, Cerebellar | Cerebellar Dysmetria | Dysmetria | Cerebellar [icd9cm.chrisendres.com]

The signs may be categorized as follows: (1) proprioceptive abnormalities manifest by flutter, dysmetria, and instability of gaze and (2) defects of vision-dependent functions [ncbi.nlm.nih.gov]

Early-Onset Spastic Ataxia - Neuropathy Syndrome

Tremor, dysmetria, and poor coordination of fine movements are often present. A sensorineural hearing loss has been found in several individuals. [disorders.eyes.arizona.edu]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

X-Linked Sideroblastic Anemia and Ataxia

(XLSA/A) is characterized by moderate anemia and early-onset spinocerebellar syndrome in males, manifest primarily as delayed walking, ataxia evident in early childhood, dysmetria [ncbi.nlm.nih.gov]

In addition to ataxia, people with this condition often have trouble coordinating movements that involve judging distance or scale (dysmetria) and find it difficult to make [ghr.nlm.nih.gov]

For X-linked anemia (ABCB7): early-onset spinocerebellar syndrome in males, manifest primarily as delayed walking, ataxia evident in early childhood, dysmetria, and dysdiadochokinesis [centogene.com]

Creutzfeldt-Jakob Disease Heidenhain Variant

In the final stages, the patient presented monophasic speech, asynergy and prevalent right limb dysmetria during spontaneous motility and startle reaction. [mdpi.com]

Six months later, her difficulties were followed by cerebellar signs (ataxia, dysmetria), myoclonus, dysphagia, and dysphonia. [content.iospress.com]

Jul. 2021 Worsening of the clinical picture, with occurrence of perceptive errors, paraphasias, myoclonus of the right upper limb and neck and dysmetria in the right side [mdpi.com]

Autosomal Recessive Spastic Ataxia Type Charlevoix-Saguenay

Saccadic dysmetria Investigations were extensive and ruled out Neimann-Pick disease, types A, B and C and atypical mitochondrial disease. [collections.lib.utah.edu]

Vertical ocular dysmetria. Am. J. Ophthal., 76; 208 – 211. Maekawa, K. and Simpson, J. I. ( 1972 ). [journals.cambridge.org]

Dysarthria, dysmetria LE > UE ATR none, Bab -/- urge incontinence urine #6 p. [ojrd.biomedcentral.com]

CAPOS Syndrome

The signs and symptoms of Cerebellar Ataxia, Areflexia, Pes Cavus, Optic Atrophy and Sensorineural Hearing Loss Syndrome may include: Areflexia Blindness Dysarthria Dysmetria [dovemed.com]

[…] girdles and hips, universal areflexia, extensor plantar reflex in the right foot and slightly extensor plantar reflex in the left, mild-to-moderate upper- and lower-limb dysmetria [elsevier.es]

He walks unaided but has mild dysmetria and ataxic gait, areflexia and pes cavus. He was treated for Wolff-Parkinson-White syndrome at age 24 years. [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Ataxia Type 2

Eye movements show horizontal bidirectional nystagmus, saccadic alterations of smooth ocular pursuit and saccadic dysmetria. 18 Supranuclear gaze palsy has been described [acnr.co.uk]