Dysmetria: Causes & Reasons

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Possible Causes for Dysmetria

Cerebellar Stroke

Andreason suggests the presence of cognitive dysmetria due to cerebellar involvement in schizophrenia which is analogous to motor dysmetria so far described in cerebellar [ijpm.info]

Dysmetria and ataxia were most resistant to rehabilitation. [cerebellumandataxias.biomedcentral.com]

Dysfunctional cortico-cerebellar circuits cause 'cognitive dysmetria' in schizophrenia. Neuroreport 1998;9:1895-9. 5. Starkstein SE, Boston JD, Robinson RG. [ijpm.info]

Autosomal Recessive Spinocerebellar Ataxia 8

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

They may also have difficulty with movements that involve judging distance or scale (dysmetria). [ghr.nlm.nih.gov]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Adult-Onset Autosomal Recessive Cerebellar Ataxia

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

A slowly progressive cerebellar syndrome with various combinations of oculomotor disorders, dysarthria, dysmetria/kinetic tremor, and ataxic gait are key presenting features [emedicine.medscape.com]

Spinocerebellar Ataxia Type 12

[…] is a progressive autosomal-dominant disorder, caused by a CAG/CTG repeat expansion in PPP2R2B on chromosome 5q32, and characterized by tremor, gait ataxia, hyperreflexia, dysmetria [ncbi.nlm.nih.gov]

Abstract SCA12 is an autosomal dominant cerebellar ataxia characterized by onset in the fourth decade of life with action tremor of arms and head, mild ataxia, dysmetria, [ncbi.nlm.nih.gov]

[…] consent has been received Technical Information Clinical Significance: Detect repeat expansions in SCA12 gene Typical Presentation: Tremor of arms and head, mild ataxia, dysmetria [athenadiagnostics.com]

Autosomal Recessive Spinocerebellar Ataxia Type 17

SCAR17 features include non-progressive congenital cerebellar ataxia, mildly delayed walking with an unsteady gait and frequent falls, dysarthria, dysmetria, hypotonia in [malacards.org]

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [ipfs.io]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

Autosomal Recessive Spinocerebellar Ataxia

They may also have difficulty with movements that involve judging distance or scale ( dysmetria ). [en.wikipedia.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

They may also have difficulty with movements that involve judging distance or scale (dysmetria). [ghr.nlm.nih.gov]

Autosomal Recessive Spinocerebellar Ataxia 18

Phenotypic manifestations commonly consist of cerebellar dysarthria, gait ataxia, and dysmetria. [karger.com]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

[…] decreased in the lower limbs, his deep tendon reflexes were hyporeflexic in all the limbs, Babinski signs were absent bilaterally, and he had bilateral upper and lower limb dysmetria [synapse.koreamed.org]

Autosomal Recessive Spastic Ataxia with Leukoencephalopathy

Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. [uniprot.org]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

[…] cerebellar hemisphere) Neocerebellum Connected with Pons and cortex through thalalmus Planning and initiation of movements Regulation of fine limb movements Limb ataxia: Dysmetria [slideshare.net]

Lateral Medullary Syndrome

Half of the patients had permanent saccadic dysmetria. [ncbi.nlm.nih.gov]

[…] loss of pain and temperature sensation from the face, ipsilateral paralysis of the larynx, pharynx, and palate, ipsilateral Horner’s syndrome, and ipsilateral dystaxia, dysmetria [boardprep.net]

Signs included anisocoria (ipsilateral Horner’s sign), right ptosis, nystagmus, dysmetria, Romberg’s sign, ataxia, and hypalgesia in left leg. [pediatricneurologybriefs.com]

Spinocerebellar Ataxia Type 10

Clinical features include dysmetria of limbs, gait ataxia, dysarthria and gaze evoked nystagmus with fragmented pursuit. [annalsofian.org]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

On examination, she had horizontal and vertical nystagmus, fragmented ocular pursuit, ocular dysmetria, scanning speech, mild limb and gait ataxia with a widened base, slow [ng.neurology.org]

Infantile-Onset Autosomal Recessive Non-Progressive Cerebellar Ataxia

Language development deficit Late-onset speech development Poor language development Speech and language delay Speech and language difficulties Speech delay [ more ] 0000750 Dysmetria [rarediseases.info.nih.gov]

In addition to these eye movement abnormalities, patients had developmental delays and ataxia, nystagmus, dysarthria, tremor, dysmetria, and seizures The epilepsies. [epilepsygenetics.net]

Spinocerebellar Ataxia Type 5

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Examination was noteworthy for mild dysarthria, slowing of saccades and gaze-holding difficulty, diffuse hyporeflexia, mild dysmetria and dysdiadochokinesis, and gait ataxia [jamanetwork.com]

abnormal ramp tracking in the upper limbs, and dyssynergia and dysmetria in the lower limbs. [jnnp.bmj.com]

Cerebellar Neoplasm

Tumors of the cerebellum Supplemental material : Video of saccadic dysmetria (same patient as above). [dizziness-and-balance.com]

Lesions involving the cerebellar hemispheres are more likely to show limb ataxias and associated dysmetria. [clinicalgate.com]

[…] quadrantanopia, behavioral alterations Occipital lobe Contralateral hemianopia Thalamus Contralateral sensory loss, behavioral changes, language disorder Cerebellum Ataxia, dysmetria [aafp.org]

Spinocerebellar Ataxia Type 1

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Abnormality of this is called dysmetria. [stanfordmedicine25.stanford.edu]

DTRs can be exaggerated, and dysmetria is common. The mean age of onset is about age 40. Some cognitive decline may occur. [disorders.eyes.arizona.edu]

Friedreich Ataxia

We describe two sisters with early onset gait ataxia, rapid disease progression, absent or very mild dysarthria and upper limb dysmetria, retained knee jerks in one, slight [ncbi.nlm.nih.gov]

Friedreich Ataxia (FA) is a neurodegenerative disorder characterised by progressive gait disturbance, dysarthria, dysmetria and other coordination disorders. [ncbi.nlm.nih.gov]

Clinical features Neurological Progressive ataxia (muscle weakness and impaired coordination) of all limbs Bilateral lower limbs equally affected Wide-based steppage gait with dysmetria [amboss.com]

Autosomal Recessive Spastic Paraplegia Type 20

Childhood onset Symptoms begin in childhood 0011463 Difficulty walking Difficulty in walking 0002355 Drooling Dribbling 0002307 Dysarthria Difficulty articulating speech 0001260 Dysmetria [rarediseases.info.nih.gov]

The role of the cerebellum in cognition and emotion: personal reflections since 1982 on the dysmetria of thought hypothesis, and its historical evolution from theory to therapy [elsevier.es]

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

Autosomal Recessive Spastic Paraplegia Type 26

[…] reported manifestations include skeletal abnormalities (i.e. pes cavus, scoliosis ), dyskinesia, dystonia, cataracts, cerebellar signs (i.e. saccadic dysfunction, nystagmus, dysmetria [rarediseases.info.nih.gov]

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Dysequilibrium Syndrome

[…] difficulties Speech delay [ more ] 0000750 Dysarthria Difficulty articulating speech 0001260 Dysdiadochokinesis Difficulty performing quick and alternating movements 0002075 Dysmetria [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 44

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Spinocerebellar Ataxia Type 14

abnormal ramp tracking in the upper limbs, and dyssynergia and dysmetria in the lower limbs. [jnnp.bmj.com]

FGF14 13q34 SCA35 40-48 years Unknown gait and limb ataxia, dysarthria, ocular dysmetria, intention tremor, pseudobulbar palsy, spasmodic torticollis, extensor plantar responses [en.wikipedia.org]

During the last two decades there has been a growing interest for the cerebellum’s role also in non-motor functions, with the introduction of the “dysmetria of thought”-hypothesis [bmcneurol.biomedcentral.com]

Niemann-Pick Disease Type C

We clinically evaluated patients' neurological involvement, giving a score of severity ranging from 0 (best) to 3 (worst) for gait abnormalities, dystonia, dysmetria, dysarthria [ncbi.nlm.nih.gov]

Neurological examination revealed a broad-based ataxic gait, limb dysmetria, downward vertical gaze palsy, brisk lower limb reflexes and ankle clonus, while neuropsychological [ncbi.nlm.nih.gov]

Typical neurological manifestations include vertical supranuclear gaze palsy, saccadic eye movement abnormalities, cerebellar ataxia, dystonia, dysmetria, dysphagia and dysarthria [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 35

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

Eye movements show horizontal bidirectional nystagmus, saccadic alterations of smooth ocular pursuit and saccadic dysmetria. 18 Supranuclear gaze palsy has been described [acnr.co.uk]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Cerebellar Disease

The graphs in this article illustrate ocular flutter, dysmetria, abnormal (nonsmooth) pursuit, instability of fixation, faulty vestibular suppression, impaired optokinetic [ncbi.nlm.nih.gov]

(From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141) Cerebellar Ataxia Adiadochokinesis | Ataxia, Cerebellar | Cerebellar Dysmetria | Dysmetria | Cerebellar [icd9cm.chrisendres.com]

The signs may be categorized as follows: (1) proprioceptive abnormalities manifest by flutter, dysmetria, and instability of gaze and (2) defects of vision-dependent functions [ncbi.nlm.nih.gov]

Early-Onset Spastic Ataxia - Neuropathy Syndrome

Tremor, dysmetria, and poor coordination of fine movements are often present. A sensorineural hearing loss has been found in several individuals. [disorders.eyes.arizona.edu]

Cardinal features - Cerebellar pathology – Stance and gait – Poor regulation and coordination of skilled movements (Dysmetria and dysdiadokinesia) – Eye movement disturbances [slideshare.net]

X-Linked Sideroblastic Anemia and Ataxia

(XLSA/A) is characterized by moderate anemia and early-onset spinocerebellar syndrome in males, manifest primarily as delayed walking, ataxia evident in early childhood, dysmetria [ncbi.nlm.nih.gov]

In addition to ataxia, people with this condition often have trouble coordinating movements that involve judging distance or scale (dysmetria) and find it difficult to make [ghr.nlm.nih.gov]

For X-linked anemia (ABCB7): early-onset spinocerebellar syndrome in males, manifest primarily as delayed walking, ataxia evident in early childhood, dysmetria, and dysdiadochokinesis [centogene.com]

CAPOS Syndrome

The signs and symptoms of Cerebellar Ataxia, Areflexia, Pes Cavus, Optic Atrophy and Sensorineural Hearing Loss Syndrome may include: Areflexia Blindness Dysarthria Dysmetria [dovemed.com]

[…] girdles and hips, universal areflexia, extensor plantar reflex in the right foot and slightly extensor plantar reflex in the left, mild-to-moderate upper- and lower-limb dysmetria [elsevier.es]

He walks unaided but has mild dysmetria and ataxic gait, areflexia and pes cavus. He was treated for Wolff-Parkinson-White syndrome at age 24 years. [ojrd.biomedcentral.com]

Autosomal Recessive Spastic Ataxia Type Charlevoix-Saguenay

Dysarthria, dysmetria LE > UE ATR none, Bab -/- urge incontinence urine #6 p. [ojrd.biomedcentral.com]

Saccadic dysmetria Investigations were extensive and ruled out Neimann-Pick disease, types A, B and C and atypical mitochondrial disease. [collections.lib.utah.edu]

Vertical ocular dysmetria. Am. J. Ophthal., 76; 208 – 211. Maekawa, K. and Simpson, J. I. ( 1972 ). [journals.cambridge.org]

Autosomal Recessive Spastic Paraplegia Type 49

Cerebellar signs were present in 4 patients (family I) and consisted of a dysarthric cerebellar speech, dysmetria, and abnormal rapid alternating movements in the upper extremities [ajnr.org]

A trace of terminal dysmetria may also be found in the upper limbs, but more florid cerebellar signs are not seen. [jnnp.bmj.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Spinocerebellar Ataxia Type 2

Whereas disease progression with prevailing ataxia and dysmetria was slow over the first symptomatic 6 years, 6 months prior to operation were characterized by the development [ncbi.nlm.nih.gov]

On neurological examination, he had bilateral external ophthalmoplegia, ataxic dysarthria, dysmetria and tremor in the upper extremities, and marked gait ataxia. [ncbi.nlm.nih.gov]

Gait ataxia, dysarthria, dysmetria, nystagmus, muscle wasting and dystonia are seen in the late stages of the disease. [patient.info]

Autosomal Recessive Spastic Ataxia Type 2

Eye movements show horizontal bidirectional nystagmus, saccadic alterations of smooth ocular pursuit and saccadic dysmetria. 18 Supranuclear gaze palsy has been described [acnr.co.uk]