Dysmetria & Proximal Muscle Weakness - Less Severe: Causes & Reasons

Possible Causes for Dysmetria & Proximal Muscle Weakness - Less Severe

Tumors of the cerebellum Supplemental material : Video of saccadic dysmetria (same patient as above). [dizziness-and-balance.com]

Mild distal weakness 2° axonal neuropathy: Less prominent than sensory change Proximal weakness 2° type II muscle fiber atrophy Progression Slow Occurs later in course of [neuromuscular.wustl.edu]

Lesions involving the cerebellar hemispheres are more likely to show limb ataxias and associated dysmetria. [clinicalgate.com]

Subacute Cerebellar Degeneration

Cerebellar exam findings, such as ataxia, vertigo, and dysmetria, are associated with other forms of cerebellar insult besides inherited disorders. [clinicaladvisor.com]

The neurological examination showed preserved cognition, slowing saccadic eye movements, dysmetria, dysdiadochokinesia, and gait ataxia. [mdsabstracts.org]

Paraneoplastic Polyneuropathy

[…] positive Romberg sign which has been present for years, as well as loss of proprioception and vibration sense in both lower extremities in addition to patellar areflexia and dysmetria [jneuro.com]

& Multisystem syndromes Paraneoplastic Ataxia: General Features Onset Before neoplasm Gait disorder Clinical Pancerebellar syndrome: Symmetric; Vertigo & Nausea; Ocular dysmetria [neuromuscular.wustl.edu]

Muscular Dystrophy-Dystroglycanopathy Type C12

Other features included dysmetria, hyporeflexia, muscle weakness and atrophy, and decreased vibratory and proprioceptive sense. Several affected members had pes cavus. [findzebra.com]

SOFT TISSUE: Distal muscle weakness; Distal muscle atrophy; Proximal muscle weakness, less severe; Muscle biopsy shows myopathic changes; Denervation; Abnormal axons with [findzebra.com]

AND NECK: [Eyes]; Nystagmus SKELETAL: [Feet]; Pes cavus MUSCLE, SOFT TISSUE: Muscle atrophy NEUROLOGIC: [Central nervous system]; Progressive gait ataxia; Limb weakness; Dysmetria [findzebra.com]

Myopathy and Diabetes mellitus

At 26 years of age, she was hospitalized for diabetic ketoacidosis, soon followed by a loss of consciousness, left-sided dysmetria, and ataxic speech. [em-consulte.com]

Can also include seizures, learning disability, dementia, proximal neurogenic muscle weakness, basal ganglia abnormalities, sensorineural hearing loss, short stature, CPEO [nature.com]

Four months later, she was admitted to a hospital because of diabetic ketoacidosis and thereafter developed a consciousness loss, left-sided dysmetria, and ataxic speech. [em-consulte.com]

Paraneoplastic Neurologic Syndrome

Clinical findings included dysmetria, dysdiadochokinesis, tremor, muscular hypotonia and gait ataxia. [jneuroinflammation.com]

[…] female, two male; median age 50 years, range 19–69) [ 33 – 36 ], all of whom presented with cerebellar gait ataxia (partly unable to walk without help) and limb ataxia (dysmetria [jneuroinflammation.com]

Enterovirus Infection

Nine days later, she presented with ataxic and wide-based gait and dysmetria affecting the extremities, with an absence of sensory nerve action potentials in the upper and [ncbi.nlm.nih.gov]

[…] affected more commonly than upper extremities (poliovirus, enterovirus 71, and coxsackievirus A7); other non-polio enteroviruses usually have less severe symptoms (for example [medicinenet.com]

Paralysis (infrequent in both polio and non-polio intro viral infections): flaccid paralysis that is often asymmetric with proximal extremity muscles affected; lower extremities [medicinenet.com]

Progressive Pseudorheumatoid Dysplasia

Laryngomalacia Cardiomegaly Choreoathetosis Clonus Abnormality of the cardiovascular system Athetosis Progressive visual loss Neurodegeneration Progressive cerebellar ataxia Dysmetria [mendelian.co]

muscle weakness Hernia Abnormal facial shape Rhizomelia Genu varum Rare Symptoms - Less than 30% cases Hydrops fetalis Decreased fetal movement Ascites Intellectual disability [mendelian.co]

[…] impairment Epiphyseal dysplasia Metaphyseal widening Limb muscle weakness Hepatomegaly Splenomegaly Talipes equinovarus Congestive heart failure Respiratory failure Myopathy Proximal [mendelian.co]

Infantile Onset Autophagic Vacuolar Myopathy

Dysmetria with dysdiadochokinesis is often present and a fine intention tremor has been observed. [disorders.eyes.arizona.edu]

• Less severe form. • Dystrophin muscle protein is deficient. [slideshare.net]

• Proximal muscle weakness of lower extremities occur first. • Onset 5-15 years or even 3rd to 4th decade. • Patients may survive till 4th or 5th decade. 21. • Laboratory [slideshare.net]

Paraneoplastic Syndrome

Midline cerebellar dysfunction (inability to stand without assistance), speech (progressive dysarthria), and nystagmus (horizontal or vertical, opsoclonus and ocular dysmetria [pulmonologyadvisor.com]

Mitochondrial Myopathy-Lactic Acidosis-Deafness Syndrome

Mitochondrial myopathy Toe walking Focal seizures with impairment of consciousness or awareness Dyspnea Increased serum pyruvate EMG abnormality Hemiparesis Focal seizures Dysmetria [mendelian.co]

Can also include seizures, learning disability, dementia, proximal neurogenic muscle weakness, basal ganglia abnormalities, sensorineural hearing loss, short stature, CPEO [nature.com]

severe variant Early childhood onset, can remain quiescent or stable into adulthood, sensorimotor neuropathy, ataxia and pigmentary retinopathy. [nature.com]

Cancer-Associated Retinopathy

[…] disease: Rare at neoplasm onset Severity: Neuropathy not disabling Associated disorder: Proximal weakness 2° Type II muscle fiber atrophy Lab Nerve conduction: Axonal loss [neuromuscular.wustl.edu]