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1,283 Possible Causes for Dysmorphic Face, Flat Supraorbital Ridges, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    Facial appearance is characteristic with narrow or triangular shaped head and high or sloping forehead, flat supraorbital ridge, scanty lateral eyebrows, short palpebral fissures[orpha.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Developmental Delay : behind schedule in reaching milestones of early childhood development Dysmorphic Face : this refers to minor facial anomalies that occur fairly frequently[ric.edu]

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org] […] fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly and wide[dx.doi.org]

    Missing: Flat Supraorbital Ridges
  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] face (bird-like), and mild to severe intellectual disability.[orpha.net] A dysmorphic face with a receding chin and a relatively big nose could also render mask ventilation difficult. [11] Dental malocclusion, receding chin, high palatal arch could[joacp.org]

    Missing: Flat Supraorbital Ridges
  • Russell-Silver Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] and further dysmorphisms.[ncbi.nlm.nih.gov] The photographs show how development of a rounder face in females and jaw growth in males lessens the dysmorphic features with age.[jmg.bmj.com]

    Missing: Flat Supraorbital Ridges
  • Simpson Dysmorphia Syndrome

    […] face, round face, hypoplastic supraorbital ridge, epicanthus, cleft palate TM Diastrophic dysplasia sulfate transporter DTDST 5q32-q33.1 222600 Diastrophic dysplasia 222600[widesmiles2.org] […] hypotrophy syndrome Intellectual disability-craniofacial dysmorphism-cryptorchidism syndrome Intellectual disability-developmental delay-contractures syndrome Intellectual[se-atlas.de] […] face -round face -hypoplastic supraorbital ridge -epicanthus -cleft palate describe diastrophic dysplasia -autosomal recessive -hypertrophic auricular cartilage -cleft palate[brainscape.com]

    Missing: Wide Space Between the First and Second Toe
  • SHORT Syndrome

    Other features can be hypoplasia of the malar bones, broad flat nasal root, prominent supraorbital ridges, relative prognathism, and mild telecanthus with or without hypertelorism[whonamedit.com] We report the two-year-four-month old female with SHORT syndrome who present growth retardation and dysmorphic features (triangular-shaped face, prominent forehead, ocular[ncbi.nlm.nih.gov] Fig. 1 Dysmorphic features (triangular-shaped face with prominent forehead and deeply-set eyes) Fig. 2 Dysmorphic features and body silhouette - front view Fig. 3 Lipodystrophy[ijponline.biomedcentral.com]

    Missing: Wide Space Between the First and Second Toe
  • Pallister-Killian Syndrome

    Craniofacial manifestations include a coarse'' face with flat profile, high forehead with temporo-frontal balding, sparseness of eyebrows and lashes, shallow supraorbital[orpha.net] ridges, hypertelorism, flat nasal bridge, long philtrum, short neck, low-implanted ears, large tongue, hypoplastic nails and small hands, sparse hair and areas of unusual[symptoma.com] The clinical phenotype is characterized by a pattern of dysmorphic features, hypo- or hyperpigmentation areas of the skin, progressive coarsening of the face with advancing[molecularcytogenetics.biomedcentral.com]

    Missing: Wide Space Between the First and Second Toe
  • Saethre-Chotzen Syndrome

    Major manifestations of the disorder are brachycephaly with variable synostosis of coronal, sagittal, and lambdoid sutures; malar hy-poplasia; shallow supraorbital ridges;[rrnursingschool.biz] Crouzon craniofacial dysostosis (OMIM 123500) involves only the face and skull.[rrnursingschool.biz] flat nasal bridge; lateral displacement of inner canthi; ocular and ear defects; and limb anomalies including brachydactyly with partial syndactyly in the hands and preaxial[rrnursingschool.biz]

    Missing: Wide Space Between the First and Second Toe
  • Gorlin-Chaudhry-Moss Syndrome

    (wide calvaria with large open anterior fontanel and wide metopic suture, broad forehead, small face, micrognathia), markedly diminished subcutaneous fat, cutis laxa and[mendelian.co] Facial dysmorphic features: Long face, prominent nose and nasal bridge, mandibular prognathism, and large ears with anteverted pinnae and increased folds.[vivavoceoralmedicineradiology.com] Petty type is a rare premature aging syndrome characterized by pre-and postnatal growth retardation, a congenital premature-aged appearance with distinctive craniofacial dysmorphism[mendelian.co]

    Missing: Wide Space Between the First and Second Toe
  • Pseudoaminopterin Syndrome

    face pelvic scapula dysplasia Short stature heart defect craniofacial anomalies Short stature hyperkaliemia acidosis Short stature locking fingers Short stature mental retardation[sosu.us] […] hypotrophy syndrome Intellectual disability-craniofacial dysmorphism-cryptorchidism syndrome Intellectual disability-developmental delay-contractures syndrome Intellectual[se-atlas.de] […] et plantaris Pallister W syndrome Tetra-amelia syndrome Adermatoglyphia Fukuyama type muscular dystrophy Campomelic dysplasia Arthrogryposis multiplex congenita whistling face[checkrare.com]

    Missing: Wide Space Between the First and Second Toe