Most patients presenting beyond the neonatal period have increased urinary glycosaminoglycans and dysostosis multiplex.
[news-medical.net]
This disorder is characterized by mental retardation, coarse faces, short stature, hearing loss, hydrocephalus, hepatosplenomegaly, dysostosis multiplex, airway obstruction
[genome.jp]
Extensive palliative care is required, patients must be regularly evaluated by echocardiogram, respiratory function, full radiologic examination to identify dysostosis multiplex
[orpha.net]