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218 Possible Causes for Dyspnea, Erythrocytes Increased, Erythrocytosis

  • Myeloproliferative Disease

    Megakaryocyte and late erythroid progenitors were dramatically increased, with only modest expansion of early erythroid progenitors.[ncbi.nlm.nih.gov] .  35 y/o previously healthy man  9 month history of tachycardia and dyspnea on exertion  Dec. 2011, dyspnea becomes more severe  Hospitalized in Miami when found to have[slideshare.net] Dyspnea secondary to pulmonary hematopoiesis as presenting symptom of myelofibrosis with myeloid metaplasia Am J Hematol 2006 ; 81 : 124-127 [cross-ref] [18] Kurtman C., Ozbilgin[em-consulte.com]

  • Familial Polycythemia

    The increased erythrocyte production results in thickening of the blood and an increased tendency toward clotting.[medical-dictionary.thefreedictionary.com] In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved.[ghr.nlm.nih.gov] Clinical features can include headache, dizziness, epistaxis and exertional dyspnea. Thrombotic events have been observed.[orpha.net]

  • Chronic Obstructive Pulmonary Disease

    Chronic hypoxaemia increases 2,3-diphosphoglycerate (2,3-DPG) in erythrocytes, shifting the dissociation curve to the right and therefore increasing oxygen delivery to the[dx.doi.org] MEASUREMENT OF DYSPNEA IN COPD Section: The two purposes of measuring dyspnea are: to differentiate between patients who have less dyspnea and those who have more dyspnea[dx.doi.org] […] oxygen therapy (LTOT) In the first Denver studies of ambulatory oxygen, patients with chronic stable hypoxemia experienced remarkable reductions in pulmonary hypertension and erythrocytosis[ncbi.nlm.nih.gov]

  • Hypoxia

    The patient described his dyspnea as exertional progressing over 1 week to rest dyspnea. He was prescribed antiretroviral therapy but was noncompliant.[ncbi.nlm.nih.gov] These findings suggest that erythrocytosis was caused by renal ischemia due to leukemic infiltration.[ncbi.nlm.nih.gov] We describe a case of a previously healthy 58-year-old woman who presented with gradual onset shortness of breath on exertion, erythrocytosis, hypoxia and hypoxaemia.[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    The increased production of erythrocytes leads to elevated hematocrit and hemoglobin counts.[proud-pv.com] Three patients experienced serious AEs (7.7%), with 1 considered related to momelotinib (dyspnea). Peripheral neuropathy occurred in 7 (17.9%) patients (4 PV, 3 ET).[ncbi.nlm.nih.gov] Unexpectedly, the symptom of erythrocytosis disappeared after the surgery.[ncbi.nlm.nih.gov]

  • Paraneoplastic Syndrome

    […] serum levels of creatine kinase and lactate dehydrogenase (LDH) and an elevated erythrocyte sedimentation rate (ESR).[emedicine.medscape.com] Review of systems was significant for hemoptysis, dyspnea on exertion and dull achy left anterior chest and shoulder pain.[healio.com] Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas.[emedicine.medscape.com]

  • Ayerza Syndrome

    Erythrocytosis refers to an increase in the concentration of erythrocytes, however, whether measured as number of cells, hemoglobin, or packed cell volume (hematocrit).[enotes.tripod.com] Among those reported are angina, hyperactive precordium, paroxysmal nocturnal dyspnea, hemoptysis, raised jugular venous pressure, abnormal heart sounds, and edema.[symptoma.com] Ayerza's disease Ayer·za's disease ə-'yər-zəz- n a complex of symptoms marked esp. by cyanosis, dyspnea, polycythemia, and sclerosis of the pulmonary artery Ayerza ä-'yer-sä[medicine.academic.ru]

  • Taussig Bing Anomaly

    Dyspnea at rest and developmental delay are the other typical features seen. Compensatory erythrocytosis may also be observed.[symptoma.com] A 23-year-old primigravida at term, presented with grade III dyspnea (New York Heart Association grading).[aeronline.org] Although her cyanosis, clubbing, and erythrocytosis were consistent with an Eisenmenger complex, the cyanosis since birth made Taussig and Bing suspect “some totally different[ncbi.nlm.nih.gov]

  • Cyanotic Congenital Heart Disease

    Repeated phlebotomy causes iron deficiency with microcytic erythrocytes, which increases the whole blood viscosity and, therefore, can potentially accentuate rather than decrease[ncbi.nlm.nih.gov] Both infants required prostaglandin E1 infusion from early infancy, and presented with sudden onset of dyspnea and hypercapnea.[ncbi.nlm.nih.gov] A rise of hematocrit above 75% resulted in return of symptoms, possibly due to marked increase of blood viscosity.[pediatrics.aappublications.org]

  • Eisenmenger Syndrome

    Uric acid and bilirubin levels are usually increased. 4.4.[ncbi.nlm.nih.gov] […] elevated in ES patients and fell significantly with sildenafil therapy that was associated with improved exercise tolerance, implying thereby a role of J receptors in producing dyspnea[ncbi.nlm.nih.gov] When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished.[ncbi.nlm.nih.gov]

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