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578 Possible Causes for Dyspnea, Erythrocytosis, Fatigue

  • Paraneoplastic Syndrome

    The authors present a case report of a woman with presumed contact dermatitis who was diagnosed with breast cancer in the setting of progressive fatigue and muscle weakness[ncbi.nlm.nih.gov] Review of systems was significant for hemoptysis, dyspnea on exertion and dull achy left anterior chest and shoulder pain.[healio.com] Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas.[emedicine.medscape.com]

  • Myeloproliferative Disease

    Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] .  35 y/o previously healthy man  9 month history of tachycardia and dyspnea on exertion  Dec. 2011, dyspnea becomes more severe  Hospitalized in Miami when found to have[slideshare.net] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[ncbi.nlm.nih.gov]

  • Post-Polycythemia Vera Myelofibrosis

    With regard to symptoms, 43% reported fatigue and 29% reported weight loss during the six months prior to inclusion.[haematologica.org] Grade 3 AEs included anemia (n 3), neutrophil decrease (n 2), amylase increase (n 2), lipase increase (n 2), diarrhea (n 2), colitis (n 1), dyspnea (n 1), pneumonia (n 1),[hematologytimes.com] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[ncbi.nlm.nih.gov]

  • Eisenmenger Syndrome

    […] elevated in ES patients and fell significantly with sildenafil therapy that was associated with improved exercise tolerance, implying thereby a role of J receptors in producing dyspnea[ncbi.nlm.nih.gov] Heart rate recovery at the first minute (HRR 1 ) and perceived effort Borg scale for dyspnea and lower limb fatigue were recorded in both tests scenarios.[ncbi.nlm.nih.gov] When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished.[ncbi.nlm.nih.gov]

  • Chronic Obstructive Pulmonary Disease

    MEASUREMENT OF DYSPNEA IN COPD Section: The two purposes of measuring dyspnea are: to differentiate between patients who have less dyspnea and those who have more dyspnea[dx.doi.org] Pulmonary rehabilitation relieves dyspnoea and fatigue, improves emotional function and enhances the sense of control that individuals have over their condition.[ncbi.nlm.nih.gov] […] oxygen therapy (LTOT) In the first Denver studies of ambulatory oxygen, patients with chronic stable hypoxemia experienced remarkable reductions in pulmonary hypertension and erythrocytosis[ncbi.nlm.nih.gov]

  • Myocardial Infarction

    She denied any chest pain, shortness of breath, fatigue, lightheadedness, palpitations, nausea or diaphoresis. Her initial laboratory Troponin I resulted 35.9 ng/mL.[ncbi.nlm.nih.gov] […] are also important causes of dyspnea.[web.archive.org] Caruso E, Di Pino A, Poli D, Manuri L, Guccione P (2014) Erythrocytosis and severe asphyxia: two different causes of neonatal myocardial infarction.[doi.org]

  • Thalassemia

    You can also take steps on your own to cope with fatigue, such as choosing a healthy diet and exercising regularly.[mayoclinic.com] He presented with chest discomfort and progressive dyspnea. Early echocardiogram showed mild pericardial effusion.[ncbi.nlm.nih.gov] Following extensive cardiological and neurological investigation, it was felt that significant erythrocytosis was the most likely cause.[ncbi.nlm.nih.gov]

  • Pulmonary Hypertension

    Other symptoms include fatigue lethargy, loss of appetite, chest pain, cough, blood in cough, hoarseness of voice.[symptoma.com] He presented with progressive severe dyspnea on exertion and lower extremity edema.[ncbi.nlm.nih.gov] One way the body compensates is to increase the ability of the blood to carry oxygen by increasing the number of red blood cells, a condition called secondary erythrocytosis[heart.org]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Dyspnea, tachycardia and dizziness are experienced in case of severe anemia.[symptoma.com] The laboratory findings showed leuko-and erythrocytosis, increased levels of urea-BUN (32 mmol/l) and creatinine (766 mmol/l) as well as uric acid (920 mmol/l).[ncbi.nlm.nih.gov]

  • Methemoglobinemia

    Concentration, g/dL Total Hemoglobin, % Symptoms None 1.5-3.0 10-20 Cyanotic skin discoloration 3.0-4.5 20-30 Anxiety, lightheadedness, headache, tachycardia 4.5-7.5 30-50 Fatigue[doi.org] Methemoglobinemia can cause life-threatening hypoxia associated with cyanosis and dyspnea not responsive to oxygen.[ncbi.nlm.nih.gov] erythrocytosis.[nature.com]

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