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227 Possible Causes for Dyspnea, Erythrocytosis, Pruritus

  • Paraneoplastic Syndrome

    Review of systems was significant for hemoptysis, dyspnea on exertion and dull achy left anterior chest and shoulder pain.[healio.com] Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas.[emedicine.medscape.com] This 59-year-old man developed ophthalmoplegia, dysarthria, dysphagia, pruritus, ataxia, corticobulbar and corticospinal signs in association with prostate cancer.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    .  35 y/o previously healthy man  9 month history of tachycardia and dyspnea on exertion  Dec. 2011, dyspnea becomes more severe  Hospitalized in Miami when found to have[slideshare.net] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[ncbi.nlm.nih.gov] Common symptoms include: headaches blurred vision fatigue weakness dizziness itchiness (pruritus) night sweats raised blood pressure (hypertension).[leukaemia.org.au]

  • Essential Thrombocythemia

    A 52-year-old African American male with ET presented with chest pain, shortness of breath, and dyspnea on exertion.[ncbi.nlm.nih.gov] […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response[ncbi.nlm.nih.gov] […] respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    Three patients experienced serious AEs (7.7%), with 1 considered related to momelotinib (dyspnea). Peripheral neuropathy occurred in 7 (17.9%) patients (4 PV, 3 ET).[ncbi.nlm.nih.gov] Unexpectedly, the symptom of erythrocytosis disappeared after the surgery.[ncbi.nlm.nih.gov] The mean intensity of aquagenic pruritus was 4.8   1.9 points (visual analogue scale). One-third of patients with aquagenic pruritus avoided any contact with water.[ncbi.nlm.nih.gov]

  • Post-Polycythemia Vera Myelofibrosis

    Grade 3 AEs included anemia (n 3), neutrophil decrease (n 2), amylase increase (n 2), lipase increase (n 2), diarrhea (n 2), colitis (n 1), dyspnea (n 1), pneumonia (n 1),[hematologytimes.com] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[ncbi.nlm.nih.gov] "Skin mast cells in polycythaemia vera: relationship to the pathogenesis and treatment of pruritus".[en.wikipedia.org]

  • Hepatitis

    When we see erythrocytosis, we should suspect the co-existence of sleep apnea syndrome.[doi.org] When they persist, they cause prolonged jaundice, elevated alkaline phosphatase, and pruritus, despite general regression of inflammation.[merckmanuals.com] Pruritus and localised hepatic discomfort or pain may follow. 7 The duration of illness varies.[immunisationhandbook.health.gov.au]

  • Carcinoid Tumor

    We describe the case of a female patient, 21 years old, complaining of dyspnea attacks and wheezing 2 years ago.[ncbi.nlm.nih.gov] […] less than 10% of the cases); then, the following may be noted: Increased blood pressure (hypertension) Increased calcium in blood (hypercalcemia) Increased red blood cells (erythrocytosis[dovemed.com] Case report We report the case of a 19 years-old woman with history of pruritus, jaundice, weight loss, and anorexia.[scielo.isciii.es]

  • Ayerza Syndrome

    Among those reported are angina, hyperactive precordium, paroxysmal nocturnal dyspnea, hemoptysis, raised jugular venous pressure, abnormal heart sounds, and edema.[symptoma.com] Chronic relative polycythemia or erythrocytosis has been variously called Gaisbock syndrome, stress erythrocytosis, benign polycythemia or erythrocytosis, benign erythrocytosis[enotes.tripod.com] Ayerza's disease Ayer·za's disease ə-'yər-zəz- n a complex of symptoms marked esp. by cyanosis, dyspnea, polycythemia, and sclerosis of the pulmonary artery Ayerza ä-'yer-sä[medicine.academic.ru]

  • Chronic Eosinophilic Leukemia

    A 54-year-old man presenting with a cough and dyspnea was diagnosed with acute eosinophilic pneumonia.[ncbi.nlm.nih.gov] .: JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 356 (5): 459-68, 2007.[northshore.org] The most common drug-related nonhematologic grade 3/4 adverse event was pruritus, which occurred in 2 patients (12.5 %).[ncbi.nlm.nih.gov]

  • Acute Mountain Sickness

    […] manifestations of acute mountain sickness (1) Headache (Severe and persistent) (2) Lassitude (3) Drowsiness/Dizziness (4) Chilliness/Nausea and vomiting (5) Facial pallor/Dyspnea[quizlet.com] Laboratory tests like complete blood count may be abnormal with elevated hematocrit, and erythrocytosis while arterial blood gas analysis will reveal respiratory alkalosis[symptoma.com] […] receiving prophylactic agents for AMS Difficulty in falling asleep 1 (0.98) 1 (0.98) Light sleep 3 (2.94) 1 (0.98) Dizziness 2 (1.96) 0 (0.00) Drowsiness 2 (1.96) 0 (0.00) Pruritus[bmccomplementalternmed.biomedcentral.com]

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