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10 Possible Causes for Dyspnea, Impaired Exercise Tolerance, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] Patients may complain of: Fatigue Pallor Weakness Headache Palpitations Dizziness Dyspnea Irritability Poor concentration, impaired development Hair loss Impaired temperature[symptoma.com] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.com]

  • Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] […] include fatigue, pallor, tachycardia, poor exercise tolerance, and suboptimal work performance. 14 Depleted blood reserves during delivery may increase the need for blood[bloodjournal.org] Acute anemia presents with symptoms owing to acute blood loss; chronic anemia may present with worsening fatigue, dyspnea, lightheadedness, or chest pain.[ncbi.nlm.nih.gov]

  • Congestive Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] The impairment of exercise tolerance indicated by NYHA classification was markedly improved by PD for both groups.[ncbi.nlm.nih.gov] Features due to left heart failure: Dyspnea, orthopnea and paroxysmal nocturnal dyspnea: These symptoms develop due to congestion of the lungs.[symptoma.com]

  • Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] Numerous mechanisms unrelated to hemodynamic dysfunction may underlie impaired exercise tolerance in patients with chronic heart failure.[doi.org] We introduced oxycodone for medically refractory dyspnea instead of morphine because of the patient's renal insufficiency.[ncbi.nlm.nih.gov]

  • Aplastic Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Other common symptoms of aplastic anemia are chest pain, pale skin, excessively cold extremities, headaches, dyspnea and dizziness shortly after standing.[symptoma.com] Aplastic anemia may present with the following signs and symptoms: Fatigue Dyspnea on exertion Easy bruising and bleeding (for example, epistaxis, gum bleeding, heavy menses[cancertherapyadvisor.com]

  • Myelodysplasia

    May be asymptomatic Disease is generally indolent, with blood counts remaining relatively stable over months or longer Most common symptoms Pallor, weakness, exertional dyspnea[arupconsult.com] ., fatigue/dyspnea, bruising/bleeding, and infections).[clinicaladvisor.com] […] count (more than 75,000 per cubic millimeter, with a baseline mean value of 99,000 per cubic millimeter) during a 2-week hiatus in study treatment because of unexplained dyspnea[doi.org]

  • Acute Myelocytic Leukemia

    The only significant difference in blood-cell indexes was an increase in red-cell distribution width (13.8% vs. 13.4% in normocytic subjects, P 0.002 by Wilcoxon rank-sum[doi.org] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Anemia manifests in the form of pallor, fatigue, weakness, dizziness, dyspnea on exertion, and possibly chest pain.[symptoma.com]

  • Severe Aplastic Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] […] male patient with hemochromatosis due to multiple packed red blood cell transfusions was referred to our emergency center for the treatment of severe aplastic anemia and dyspnea[ncbi.nlm.nih.gov] Patients may report tachycardia, palpitations and dyspnea, particularly when under exercise. They may appear cyanotic.[symptoma.com]

  • Anemia of Chronic Disease

    The hemoglobin levels range from 7.0 to 11.0 g/dL, and the red blood cells (RBCs) vary little with a normal or slightly increased red cell distribution width (RDW), mean corpuscular[clinicaladvisor.com] […] progression; Increased cardiovascular morbidity and mortality ; Reduced exercise tolerance, angina, and worsening of heart failure (where this already exists); Poorer organ[myvmc.com] COPD patients and has a negative impact on dyspnea and circulatory efficiency during exercise.[ncbi.nlm.nih.gov]

  • Acquired Spherocytosis

    The red blood cell distribution width (RDW) index (RDW-CV and RDW-SD) showed a trend similar to MCV and increased significantly from day 35 onward ( Table 1 ).[mdpi.com] Symptoms: fatigue, weakness, shortness of breath, chest pain, low exercise tolerance, lightheadedness, cognitive impairment. Key management points 1.[cancertherapyadvisor.com] Within minutes, the patient may develop fever, chills, dyspnea, hypotension, and shock.[aafp.org]

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