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46 Possible Causes for Dyspnea, Lactate Dehydrogenase Increased, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] Patients may complain of: Fatigue Pallor Weakness Headache Palpitations Dizziness Dyspnea Irritability Poor concentration, impaired development Hair loss Impaired temperature[symptoma.com] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.com]

  • Thalassemia

    At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[ncbi.nlm.nih.gov] blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] He presented with chest discomfort and progressive dyspnea. Early echocardiogram showed mild pericardial effusion.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    He presented with progressive severe dyspnea on exertion and lower extremity edema.[ncbi.nlm.nih.gov] Major dyspnea, hemodynamic distress and fever were noted on physical examination. Biological tests exploring anaemia revealed Haemoglobin (Hb) S levels of 39.1%.[ncbi.nlm.nih.gov] Dyspnea suggests acute chest syndrome, pulmonary hypertension, and/or CHF.[web.archive.org]

  • Folate-Deficiency Anemia

    Folate-deficiency anemia causes symptoms that are common for all types of anemia, like fatigue, irritability, headaches, diminished concentration ability, dyspnea, and palpitations[symptoma.com] Additional common symptoms include aches and pains, muscle weakness, and difficulty breathing (dyspnea).[rarediseases.org]

  • Autoimmune Hemolytic Anemia

    Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] The patient suddenly developed hematuria and dyspnea on exertion while receiving adalimumab treatment.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    The only significant difference in blood-cell indexes was an increase in red-cell distribution width (13.8% vs. 13.4% in normocytic subjects, P 0.002 by Wilcoxon rank-sum[doi.org] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Anemia manifests in the form of pallor, fatigue, weakness, dizziness, dyspnea on exertion, and possibly chest pain.[symptoma.com]

  • Cooley's Anemia

    […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org]

  • Vitamin B12 Deficiency

    The hematological changes in vitamin B12 deficiency present as megaloblastic anemia, increased lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and[ncbi.nlm.nih.gov] […] of cobalamin deficiency ranges from the incidental increase of mean corpuscular volume and neutrophil hypersegmentation to symptoms due to severe anemia, such as angor, dyspnea[ncbi.nlm.nih.gov] Cardiovascular symptoms include syncope, dyspnea, orthopnea, palpitations, and angina.[emedicine.medscape.com]

  • Anemia

    Increasing platelet count, decreasing lactate dehydrogenase (LDH), and decreasing red blood cell (RBC) fragments indicate a positive response to treatment.[emedicine.com] […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Acute anemia presents with symptoms owing to acute blood loss; chronic anemia may present with worsening fatigue, dyspnea, lightheadedness, or chest pain.[ncbi.nlm.nih.gov]

  • Immune Hemolytic Anemia

    Expected laboratory findings in AIHA include positive direct antiglobulin test (DAT), decreased haptoglobin, increased indirect bilirubin, increased lactate dehydrogenase[xpertdox.com] AIHA is characterized by hemolytic anemia, which is most often revealed by an unusual weakness and fatigue with tachycardia and exertional dyspnea, and also in some cases[orpha.net] If the anemia is severe enough, the patient will present with symptoms of fatigue, weakness, dizziness, and dyspnea. It is rare to see symptoms of bleeding.[clinicaladvisor.com]

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