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25 Possible Causes for Dyspnea, Nail Abnormality, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] Patients may complain of: Fatigue Pallor Weakness Headache Palpitations Dizziness Dyspnea Irritability Poor concentration, impaired development Hair loss Impaired temperature[symptoma.com] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.com]

  • Folate-Deficiency Anemia

    Folate-deficiency anemia causes symptoms that are common for all types of anemia, like fatigue, irritability, headaches, diminished concentration ability, dyspnea, and palpitations[symptoma.com] Severe anaemia is indicated if any of these is abnormally pale.[southsudanmedicaljournal.com] Additional common symptoms include aches and pains, muscle weakness, and difficulty breathing (dyspnea).[rarediseases.org]

  • Sickle Cell Disease

    He presented with progressive severe dyspnea on exertion and lower extremity edema.[ncbi.nlm.nih.gov] Major dyspnea, hemodynamic distress and fever were noted on physical examination. Biological tests exploring anaemia revealed Haemoglobin (Hb) S levels of 39.1%.[ncbi.nlm.nih.gov] Dyspnea suggests acute chest syndrome, pulmonary hypertension, and/or CHF.[web.archive.org]

  • Iron Deficiency

    Average size of RBCs (MCV) — may be decreased Average amount of Hb in RBCs (MCH) — may be decreased Increased variation in the size of RBCs (red cell distribution width (RDW[labtestsonline.org.au] Patients may have pica, an abnormal craving to eat substances (eg, ice, dirt, paint).[merckmanuals.com] The physiological consequences include fatigue, lethargy, and dyspnea; conversely, iron repletion in iron-deficient individuals has been shown to improve exercise capacity[ncbi.nlm.nih.gov]

  • Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Acute anemia presents with symptoms owing to acute blood loss; chronic anemia may present with worsening fatigue, dyspnea, lightheadedness, or chest pain.[ncbi.nlm.nih.gov] […] months Leukemia, myelofibrosis Usually spontaneous, but rates are increased in patients with prior radiation exposure or chemotherapy Anemia causes pallor, fatigue, and dyspnea[aafp.org]

  • Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] We introduced oxycodone for medically refractory dyspnea instead of morphine because of the patient's renal insufficiency.[ncbi.nlm.nih.gov] Compared with control group, there was no effect on dyspnea improvement.[ncbi.nlm.nih.gov]

  • Microcytic Anemia

    […] decreased Normal to increased Red blood cell distribution width measures the variation in red blood cell size and is often increased in persons with iron deficiency, but[aafp.org] Brittle or rigid fingernails may be a result of abnormal thinness of nails due to insufficient iron supply.[newworldencyclopedia.org] […] does not typically exhibit many symptoms and those which are present are things like headache, fatigue, dizziness, tachycardia, orthostatic hypertension, and exertional dyspnea[physicianassistantexamreview.com]

  • Acquired Sideroblastic Anemia

    Red cell distribution width is increased. White blood cells and platelets are normal.[encyclopedia.com] Moderate to severe anemia with fatigue, dizziness, and dyspnea should prompt an evaluation for SA.[5minuteconsult.com] As noted above, examination of the peripheral blood smear for a dimorphic picture, an elevated red cell distribution width (RDW) value, and the presence of siderotic granules[psychiatryadvisor.com]

  • Sideroblastic Anemia

    Red cell distribution width is increased. White blood cells and platelets are normal.[encyclopedia.com] Moderate to severe anemia with fatigue, dizziness, and dyspnea should prompt an evaluation for SA.[5minuteconsult.com] As noted above, examination of the peripheral blood smear for a dimorphic picture, an elevated red cell distribution width (RDW) value, and the presence of siderotic granules[psychiatryadvisor.com]

  • Hereditary Sideroblastic Anemia

    More commonly, female carriers of the disease have an increased red blood cell distribution width and sometimes erythrocyte dimorphism ({18:Fleming, 2002}).[diseaseinfosearch.org] Moderate to severe anemia with fatigue, dizziness, and dyspnea should prompt an evaluation for SA.[5minuteconsult.com] Red cell distribution width is increased. White blood cells and platelets are normal.[encyclopedia.com]

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