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60 Possible Causes for Dyspnea, Red Blood Cell Distribution Width Increased, Splenomegaly

  • Thalassemia

    blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Approach to the adult patient with splenomegaly and other splenic disorders. . Accessed June 14, 2016. Splenomegaly. Merck Manual Professional Version. .[mayoclinic.org] He presented with chest discomfort and progressive dyspnea. Early echocardiogram showed mild pericardial effusion.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    In two mouse SCD models, Berkeley and SAD, inhibition of red blood cell dehydration and sickling was achieved with correction of hematological parameters, splenomegaly, and[ncbi.nlm.nih.gov] He presented with progressive severe dyspnea on exertion and lower extremity edema.[ncbi.nlm.nih.gov] […] index of suspicion is therefore required for the diagnosis of such cases in a nonendemic area like Delhi specifically in patients who presented with unexplained anemia and splenomegaly[doi.org]

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] […] symptoms Physical findings: Impaired growth and development in children Pallor of the mucous membranes Spoon-shaped nails with decreased capillary refill Angular stomatitis Splenomegaly[symptoma.com] (a nonspecific finding) Spoon-shaped nails (koilonychia) A glossy tongue, with atrophy of the lingual papillae Fissures at the corners of the mouth (angular stomatitis) Splenomegaly[emedicine.com]

  • Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] Some of the extracardiac signs of heart failure are ascites, bronchial wheezing, hydrothorax, edema, liver enlargement, moist rales, and splenomegaly.[medical-dictionary.thefreedictionary.com] We introduced oxycodone for medically refractory dyspnea instead of morphine because of the patient's renal insufficiency.[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] May be asymptomatic Disease is generally indolent, with blood counts remaining relatively stable over months or longer Most common symptoms Pallor, weakness, exertional dyspnea[arupconsult.com] We present a 2-year-old boy with splenomegaly, leukocytosis, thrombocytopenia, anemia, and excess myeloblasts with easily seen Auer rods, and marked dysgranulopoiesis and[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] The patient suddenly developed hematuria and dyspnea on exertion while receiving adalimumab treatment.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    The only significant difference in blood-cell indexes was an increase in red-cell distribution width (13.8% vs. 13.4% in normocytic subjects, P 0.002 by Wilcoxon rank-sum[doi.org] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Anemia manifests in the form of pallor, fatigue, weakness, dizziness, dyspnea on exertion, and possibly chest pain.[symptoma.com]

  • Essential Thrombocythemia

    In this regard, one must carefully examine the complete blood count (anemia or leukocytosis suggest early/prefibrotic MF), peripheral blood smear (increased red cell distribution[doi.org] […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov] A 52-year-old African American male with ET presented with chest pain, shortness of breath, and dyspnea on exertion.[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Splenomegaly, episodes of jaundice and roentgenologic evidence of bone involvement were prominent features.[jamanetwork.com] Hepato-splenomegaly has been contained to a modest level; hyperspienism has not developed.[nature.com]

  • Folate-Deficiency Anemia

    Physical examination revealed anemia, jaundice and marked splenomegaly.[ci.nii.ac.jp] Folate-deficiency anemia causes symptoms that are common for all types of anemia, like fatigue, irritability, headaches, diminished concentration ability, dyspnea, and palpitations[symptoma.com] On abdominal examination there was palpable splenomegaly but not other organomegaly or ascites.[casesjournal.biomedcentral.com]

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