Create issue ticket

1,402 Possible Causes for Ear Deformity, Preaxial Polysyndactyly, Wide Space Between the First and Second Toe

  • Kleiner Holmes Syndrome

    His younger brother had preaxial polysyndactyly of the great toes.[omim.org] […] crus; Small ears; Low-set ears; Apical cartilage deformity; Deafness; Shallow orbits; Hypertelorism; Plagiocephaly (asymmetry of orbits); Strabismus; Buphthalmos; Ptosis;[panelapp.genomicsengland.co.uk] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov]

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org] […] fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly and wide[dx.doi.org]

    Missing: Preaxial Polysyndactyly
  • Atelosteogenesis Type 2

    Feet with preaxial polysyndactyly and clubfoot. Sprengel anomaly. Cardiac and genitourinary anomalies.[musculoskeletalkey.com] Associated malformations include urinary tract duplication, hydronephrosis, cleft palate, ear deformities, corneal clouding and blue sclera, anal atresia and aplastic testis[fetalultrasound.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Seckel Syndrome

    ears lacking lobules, skeletal malformations, mental retardation, and developmental delay.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Preaxial Polysyndactyly
  • Craniosynostosis-Dandy-Walker Malformation-Hydrocephalus Syndrome

    Five children are described with a striking, asymmetric facial appearance, craniosynostosis , preaxial polysyndactyly, agenesis of the corpus callosum and unusual skin with[ihop-net.org] deformity) and variable developmental delay.[malacards.org] […] sagittal craniosynostosis (see this term), Dandy-Walker malformation, hydrocephalus, craniofacial dysmorphism (including dolichocephaly, hypertelorism, micrognathia, positional ear[malacards.org]

    Missing: Wide Space Between the First and Second Toe
  • Microtia

    Microtia and Other Ear Deformities Congenital ear deformities occur in many different syndromes or alone.[cranioutah.com] The Microtia – Congenital Ear Deformity Institute has evaluated and performed thousands of surgeries in order to correct children’s ear deformities.[microtia.net] All ears were graded based on the severity of ear deformity using the Jahrsdoerfer system, based on findings on computed tomography of the temporal bone.[ncbi.nlm.nih.gov]

    Missing: Preaxial Polysyndactyly Wide Space Between the First and Second Toe
  • Familial Congenital Nasolacrimal Duct Obstruction

    polysyndactyly of the feet, soft tissue syndactyly of the hands, and brachydactyly and duplication of the second toe may be seen in many of these patients.[entokey.com] Deformities, Acquired Ear Diseases Ear Neoplasms Earache Eating Disorders Ebstein's Anomaly Ecchymosis Echinococcosis Echinococcosis, Hepatic Echinococcosis, Pulmonary Echinostomiasis[medgene.med.harvard.edu] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Facioauriculoradial Dysplasia

    polysyndactyly, genitourinary anomalies, dysmorphic facies, anonychia Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly 119800[docksci.com] deformity is described in a mother and her daughter.[jmg.bmj.com] Abstract A syndrome characterised by asymmetrical radial dysplasia, dysmorphic facies, conductive deafness, and external ear deformity is described in a mother and her daughter[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Dubowitz Syndrome

    In addition, the eyes may be small and wide set, and the affected individual may have low-set ears.[wisegeek.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Telecanthus, visual deficits, a cleft palate and several other facial deformities are less commonly encountered.[symptoma.com]

    Missing: Preaxial Polysyndactyly
  • Mandibulofacial Dysostosis

    These were correlated with induced ear deformities in an animal model that had features characteristic of human mandibulofacial dysostosis.[ncbi.nlm.nih.gov] RESULTS: The course of the facial nerve was not significantly different in terms of the severity of microtia and deformity of the middle ear.[ncbi.nlm.nih.gov] This deafness is due to a wide range of deformities of the ossicular chain associated with a characteristic reduction in the size of the middle ear cavity.[ncbi.nlm.nih.gov]

    Missing: Preaxial Polysyndactyly Wide Space Between the First and Second Toe