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68 Possible Causes for Earlier Onset May Occur, Hypercholesterolemia

  • Familial Hypercholesterolemia

    It is possible, however, that the benefits of treatment were less in men, because the onset of coronary disease occurs 10 years earlier than in women 4–6 and consequently[doi.org] PURPOSE OF REVIEW: Hypercholesterolemia (HC), or high cholesterol, is usually caused by diet, other health conditions, or inherited diseases, such as familial hypercholesterolemia[ncbi.nlm.nih.gov] Familial hypercholesterolemia (FCH) is a rather common genetic disorder characterized by prominent hypercholesterolemia due to the selective elevation of low-density lipoproteins[symptoma.com]

  • Diabetes Mellitus

    The increased risk or earlier onset of age-related cataracts in diabetic patients may be a result of the accumulation of sorbitol within the lens and accompanying changes[aao.org] At baseline, no patients in the DCCT had hypertension or hypercholesterolemia, on the basis of the standards at the time, and only 5 percent had microalbuminuria (urinary[doi.org] Diabetic patients develop age-related lens changes that are indistinguishable from nondiabetic age-related cataracts, except that these lens changes tend to occur at a younger[aao.org]

  • Musculoskeletal Lower Back Pain

    Information on medical conditions diagnosed by physicians such as diabetes mellitus, hypertension, cardiovascular disease and hypercholesterolemia were self-reported.[journals.plos.org] […] in adolescence, it may be necessary to investigate the condition in this stage of life (or earlier) to identify the initial onset.[chiro.org] […] exacerbations and remissions, with the most consistent predictor of a new episode being experience of a previous episode. [ 10 ] Given that the rise in prevalence of MSK conditions occurs[chiro.org]

  • CADASIL Syndrome

    Diagnosis is usually made around age 45, but greater attention to relatives of affected patients to detect neurological and psychiatric manifestations may lead to an earlier[doi.org] Medications for hypertension and hypercholesterolemia are also beneficial in patients with CADASIL syndrome.[brighthub.com] Symptomatic treatment can be offered to patients to treat migraines and potential concomitant vascular risk factors (hypertension, hypercholesterolemia and diabetes).[orpha.net]

  • Aortic Valve Calcification

    BACKGROUND: Familial hypercholesterolemia is typically caused by LDL receptor (LDLR) mutations that result in elevated levels of LDL cholesterol (LDL-C).[ncbi.nlm.nih.gov] Hypertension occurs in up to 40% to 50% of patients with calcific aortic stenosis and should be managed appropriately, because untreated hypertension may lead to earlier onset[columbiasurgery.org] […] vascular and valvular atherosclerotic lesions, others, such as rabbits and mice, have not been shown to develop lesions naturally and require an inciting factor, such as hypercholesterolemia[ncbi.nlm.nih.gov]

  • Menopause

    The median age for menopause is 51, though it may occur on average up to two years earlier for African-American and Latina women.[healthline.com] Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women. N Engl J Med . 1997 Aug 28. 337(9):595-601. [Medline] .[emedicine.medscape.com] Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women. N Engl J Med. 1997 Aug 28. 337(9):595-601. [Medline].[emedicine.medscape.com]

  • Alzheimer Disease

    […] career, as the demands and events that occur soon after caregiving onset may precipitate early institutionalization or other outcomes.[doi.org] Based on epidemiologic studies, both cross-sectional and longitudinal, there are statistically significant correlations between the prevalence of AD and diabetes, hypercholesterolemia[ncbi.nlm.nih.gov] The potential disease-modifying effects of simvastatin on CSF phospho-tau should be further investigated in persons with hypercholesterolemia. 2017 American Academy of Neurology[ncbi.nlm.nih.gov]

  • Hypogonadism

    Testosterone regulates body composition (fat and lean muscle mass), and its deficiency produces impaired glucose metabolism and hypercholesterolemia.[symptoma.com] There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls.[mayomedicallaboratories.com] For boys, there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable.[mayomedicallaboratories.com]

  • Restless Legs Syndrome

    Patients with RLS and with CVD and/or hypertension were significantly older, with hypercholesterolemia, sleep apnea and older age at RLS and at daily RLS onset compared with[ncbi.nlm.nih.gov] Allen RP, Hening WA, Earley CJ (2008) Adult RLS patients show lower serum ferritin occurs with earlier age-of-onset of RLS symptoms indicating RLS may impair the normal age-related[doi.org]

  • Aortic Valve Disorder

    Aortic Valve Disease Heart Chest pain Feeling faint or fainting with exertion Shortness of breath Fatigue Heart palpitations Heart murmur Rheumatic fever Hypercholesterolemia[heartvalvedisease.nm.org] Hypertension occurs in up to 40% to 50% of patients with calcific aortic stenosis and should be managed appropriately, because untreated hypertension may lead to earlier onset[columbiasurgery.org] Diet : Because hypercholesterolemia and other coronary artery disease risk factors may accelerate the sclerosis and deterioration of a congenitally bicuspid aortic valve,[chd-uk.co.uk]

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