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31 Possible Causes for Earlier Onset May Occur, Hypertriglyceridemia

  • Diabetes Mellitus

    The reason for the latest hospitalisation was hyperglycemia, hypertriglyceridemia and elevated transaminase levels.[] The increased risk or earlier onset of age-related cataracts in diabetic patients may be a result of the accumulation of sorbitol within the lens and accompanying changes[] Current ACC/AHA guidelines continue to endorse the treatment of patients with fasting triglycerides 500 mg/dl to prevent more severe hypertriglyceridemia and pancreatitis[]

  • Familial Hypercholesterolemia

    Managing hypertriglyceridemia in special situations. Table 6. Managing hypertriglyceridemia in special situations.[] It is possible, however, that the benefits of treatment were less in men, because the onset of coronary disease occurs 10 years earlier than in women 4–6 and consequently[] Yuan G et al. (2007) Hypertriglyceridemia: its etiology, effects and treatment. CMAJ 176 : 1113–1120 5.[]

  • Launois Syndrome

    Associated disorders include liver disease, hyperlipidemia including elevated high density lipoprotein (HDL) levels (in patients with a history of alcohol use), hypertriglyceridemia[] The former is associated with larger tumors and earlier onset of disease. Acromegaly is insidious in onset, often occurring over years.[] Hyperprolactinemia is also common and may present as hypothyroidism, galactorrhea in females, and adrenal insufficiency.[]

  • Alzheimer Disease

    There are case series showing that concomitant use of omega-3 fatty acids may adequately manage hypertriglyceridemia in these patients. 25 Bexarotene in human clinical trials[] […] career, as the demands and events that occur soon after caregiving onset may precipitate early institutionalization or other outcomes.[] When used to treat cutaneous T-cell lymphoma, the drug can cause adverse effects including hypertriglyceridemia, hypercholesterolemia, and hypothyroidism; these require monitoring[]

  • Psoriasis

    […] years old. 18 After checking fasting serum lipids at the initiation of therapy, these levels can be tested at least every 6 months for evidence of hypercholesterolemia or hypertriglyceridemia[] Among children and adolescents, plaque psoriasis has been found to affect females more than males, but this observation may be due to the earlier age of onset in females.[] […] cholesterol levels 300 mg/dL warrant a discontinuation of acitretin and close monitoring of lipids until they return to baseline. 73 Sometimes, a fenofibrate is recommended for hypertriglyceridemia[]

  • Limb-Girdle Muscular Dystrophy Type 1H

    Affected patients are insulin-resistant and may develop glucose intolerance and diabetes mellitus after age 20 years, hypertriglyceridemia, and low levels of high density[] Scoliosis and joint contractures are more common with earlier disease onset.[] She had a complex past medical historywith insulin dependent diabetes mellitus since the age of23, hypertriglyceridemia, arterial hypertension and apolycystic ovary disease[]

  • Thyroid Cancer

    In rats, the drug reduces body fat accumulation, prevents liver steatosis, improves insulin sensitivity, and normalizes hypertriglyceridemia (183).[] Medullary thyroid cancer can present with earlier onset and more aggressive disease in successive generations, depending on the genotype.[] MEN2A families may exhibit some or all of these features. As an autosomal dominant syndrome, transmission can occur through maternal or paternal lineages.[]

  • Limb-Girdle Muscular Dystrophy

    […] muscular dystrophy, pronounced partial lipodystrophy, cardiac conduction defect, polycystic ovary disease and a metabolic syndrome with insulin-resistant diabetes mellitus and hypertriglyceridemia[] Scoliosis and joint contractures are more common with earlier disease onset.[] Extramuscular findings including cardiac, respiratory, ocular and CNS may occur with specific variants as detailed in the tables below. 2, 3,4,5 Table 1: Limb-girdle muscular[]

  • Emery-Dreifuss Muscular Dystrophy Type 2

    Both genetic syndromes are characterized by severe insulin resistance and hyperinsulinemia, associated with lipoatrophy, lipodystrophy, and hypertriglyceridemia.[] The age of onset of muscle weakness usually occurs at 15 years, although it may arise at earlier ( 30 years) ages.[] Scoliosis and joint contractures are more common with earlier disease onset.[]

  • Familial Cold Autoinflammatory Syndrome Type 1

    […] includes the following, based on the initial presentation: Abdominal pain, lower quadrant predominant: Acute appendicitis, porphyria, hereditary angioedema, pancreatitis (with hypertriglyceridemia[] This observation indicates that CU may occur earlier in life than previously thought, and raises the possibility that it is an under-recognized condition among the pediatric[] […] age of diagnosis is 18 years, but cases of CU have been described in infants as well. 3 A recent study evaluating 30 CU children under the age of 18 found the mean age of onset[]

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