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16 Possible Causes for Earlier Onset May Occur, Uric Acid Increased

  • Diabetes Mellitus

    The increased risk or earlier onset of age-related cataracts in diabetic patients may be a result of the accumulation of sorbitol within the lens and accompanying changes[aao.org] […] lowering uric acid levels prevented the increase in mean arterial blood pressure ( 40 ).[doi.org] […] whereas uric acid (HR per 1 mmol/L increase, 2.05) and physical inactivity during leisure time (HR, 1.80) were associated with diabetes development in women only.[doi.org]

  • Psoriasis

    Among children and adolescents, plaque psoriasis has been found to affect females more than males, but this observation may be due to the earlier age of onset in females.[emedicine.medscape.com] In psoriasis, hyperuricemia may occur by increased epidermal cell turnover, which accelerates purine metabolism and has uric acid as the product of its catabolism.[ncbi.nlm.nih.gov] acid concentration may be increased Low levels of circulating immune complexes have been detected in 56% of patients Serum immunoglobulin A levels are increased in two thirds[emedicine.medscape.com]

  • Familial Hypercholesterolemia

    It is possible, however, that the benefits of treatment were less in men, because the onset of coronary disease occurs 10 years earlier than in women 4–6 and consequently[eurheartj.oxfordjournals.org] HDL; lowers TGs (low doses), LDL-C (higher doses), and Lp(a) (secondary) Frequent adverse effects: Flushing, impaired glucose tolerance, increased uric acid Aspirin and administration[merckmanuals.com] […] men will have had more extensive atheroma that may involve the coronary ostia and aortic root, as well as the coronary arteries. 27 Furthermore, the intensity of statin treatment[eurheartj.oxfordjournals.org]

  • Agranulocytosis

    Strikingly, in a few patients, agranulocytosis occurred even after 13, 14, and 22 years of clozapine treatment, which is much later than reported earlier. 19 Late-onset agranulocytosis[psychiatrist.com] Reversible, dose-dependent and usually mild or moderate elevations of lactate dehydrogenase, alkaline phosphatase, serum uric acid, and gamma-glutamyl transpeptidase may occur[pheniciagroup.com] may affect men more than women.[psychiatrist.com]

  • Aortic Valve Insufficiency

    Hypertension occurs in up to 40% to 50% of patients with calcific aortic stenosis and should be managed appropriately, because untreated hypertension may lead to earlier onset[columbiasurgery.org] They also increase potassium and bicarbonate excretion as well as decrease calcium excretion and uric acid retention.[emedicine.medscape.com]

  • Autoimmune Thrombocytopenia

    CONCLUSIONS: From a clinical perspective, the onset of therapeutic effects of intravenous immunoglobulin in patients with ITP may occur at an earlier stage and be superior[ncbi.nlm.nih.gov] uric acid level, increased LDH level, basic metabolic panel Delivering the fetus; intravenous magnesium sulfate Recovery usually is within three days of delivery If persistent[aafp.org] […] moderate Elevated blood pressure, visual symptoms, headache, right upper quadrant abdominal pain, influenza-like symptoms CBC, liver function test, urine protein level, increased[aafp.org]

  • Renal Arteritis

    The peak incidence is in the third and fourth decades of life but the onset of illness may occur earlier, including in childhood [ 3 ].[ped-rheum.biomedcentral.com] Concomitant use of diuretics and/or cyclosporin is common and can further impair uric acid clearance and increase the risk of gout attacks.[arthritis-research.biomedcentral.com] The impaired renal uric acid clearance leads to hyperuricemia.[arthritis-research.biomedcentral.com]

  • Recurrent Jaundice of Pregnancy

    It may also appear immediately after delivery. Jaundice appears soon after onset of symptoms and can become intense in a large proportion of patients.[patient.info] Uric acid and ammonia levels can be increased. Hyperuricemia can be an early indicator and develop before hyperbilirubinemia[ 77, 78 ].[wjgnet.com] acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[clevelandclinicmeded.com]

  • Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 2

    The age of onset of muscle weakness usually occurs at 15 years, although it may arise at earlier ( 30 years) ages.[frontiersin.org] […] of arterial pressure, elevation of uric acid, hepatic steatosis, and precocious arteriosclerosis, with an increase in the risk of cardiovascular disease and predisposition[scirp.org] Scoliosis and joint contractures are more common with earlier disease onset.[now.aapmr.org]

  • Hemoglobin Yakima

    Children experiencing splenic sequestration episodes may have earlier onset of splenomegaly and a lower level of Hb F at 6 months of age. 8 Crises are often associated with[doctorlib.info] Renal profile (kidney function tests), blood sugar, electrolytes, serum iron, serum uric acid and lipid profile were normal.[sjmms.net] Splenic sequestration is characterized by a sudden trapping of blood in the spleen, which leads to a rapid decline in hemoglobin, often to less than 6 g/dL. 37 This phenomenon occurs[doctorlib.info]

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