Possible Causes for early age of onset Atopic Dermatitis age at onset Female gender The objective when treating a patient for atopic dermatitis is control of exacerbations, not elimination of the disease. [emedicine.medscape.com] Girls and patients with severe disease, early age of onset, family history, and associated allergic rhinitis or asthma are more likely to have prolonged disease. [merckmanuals.com] […] in order of relative importance) include the following: Persistent dry or itchy skin in adult life Widespread dermatitis in childhood Family history of atopic dermatitis Early [emedicine.medscape.com] Bidirectional Tachycardia An early age of onset and mortality as high as 30% by the age of 30 years has recently been described.8 In a normal cardiac cell, depolarization of the membrane initiates [ncbi.nlm.nih.gov] Late-Onset Depression Robinson First published November 1, 1989, DOI: Abstract We examined correlates of depression in patients whose onset of Parkinson's disease (PD) began before age 55 (early-onset [neurology.org] Fifteen patients (20.3%) had an early onset of depression (before age 60 years) and 59 (79.7%) had a late onset of depression. [ncbi.nlm.nih.gov] Twelve had late-onset depression (first episode over 55 years of age); 11 had early onset (first episode before 50 years). [ncbi.nlm.nih.gov] Acute Gastroenteritis […] with acute gastroenteritis were randomly assigned to “early refeeding” or “late refeeding”.51 These children were not generally malnourished before the onset of their illness [adc.bmj.com] However, antibiotics are effective in reducing symptoms only if started in the early stage of the disease (within 3 days of onset). [f1000research.com] […] malnourished children, early refeeding has been associated with significant nutritional advantages.50 In a recent multicentre European study, 230 weaned children 3 years of age [adc.bmj.com] Young-Onset Parkinson Disease Diagnostic methods Diagnosis relies on presence of the clinical symptoms with tremor present in 85% of YOPD patients, an early age at onset, a family history of PD and a positive [orpha.net] About 10 percent of Parkinson’s patients are diagnosed under age 50, which is considered early onset. Walker has no family history of the disease. [foxnews.com] Abstract We describe a personal series of 60 cases of parkinsonism with onset under the age of 40 years. [ncbi.nlm.nih.gov] Vitamin D Deficiency Dermatologists are in a unique position to introduce lifestyle modifications at an early age to their patients with acne in order to prevent or delay the onset of serious [jcadonline.eastendseo.com] Malignant Neoplasm of the Prostate The proportional hazards analyses revealed that two factors, early age at onset of disease in the proband and multiple affected family members, were important determinants [ncbi.nlm.nih.gov] The best fitting autosomal dominant model further suggested that this inherited form of prostate cancer accounts for a significant proportion of early onset disease but overall [ncbi.nlm.nih.gov] onset of prostate cancer. [ncbi.nlm.nih.gov] Dermatitis Sparing of the groin and axillary regions I mportant features — seen in most cases, adding support to the diagnosis: • Early age of onset • Atopy • Personal and/or family [aad.org] Girls and patients with severe disease, early age of onset, family history, and associated allergic rhinitis or asthma are more likely to have prolonged disease. [merckmanuals.com] Current or previous flexural lesions in any age group 3. [aad.org] Vitamin B12 Deficiency Early age at onset and increased frequency of intrinsic-factor antibody in black women. N Engl J Med. 1978 Mar 23. 298(12):647-50. [Medline]. [emedicine.medscape.com] By intervening early with parenteral vitamin B12 and nutritional assessment prior to onset of weight loss in at risk individuals, clinicians will be able to improve their [ncbi.nlm.nih.gov] In conjunction with social risk factors and physiologic changes that occur naturally with aging, this population is also at risk for developing protein malnutrition. [ncbi.nlm.nih.gov] Cystitis It is believed that many patients have early forms of IC with a delayed diagnosis. The average age of onset of IC is 40 years. What Causes Interstitial Cystitis? [emedicinehealth.com] Dysthymic Disorder DSM-III-R (American Psychiatric Association 1987) revised the dysthymia criteria by (1) distinguishing early from late age of onset; (2) providing separate designations for [ncbi.nlm.nih.gov] […] at an early age. [ncbi.nlm.nih.gov] Specify if: Early Onset: if onset is before age 21 years Late Onset: if onset is age 21 years or older Specify (for most recent 2 years of Dysthymic Disorder): With Atypical [behavenet.com] Menopause Early menopause usually refers to onset before age 45. Premature menopause or premature ovarian insufficiency occurs before age 40. [healthline.com] Menopause can occur anytime after the age of 35, but the typical age of onset is in the late 40s to early 50s; the average age of onset in American women is 51. [labtestsonline.org] The spontaneous onset of menopause before age 45 is sometimes referred to as early menopause. [britannica.com] Anemia Early age at onset and increased frequency of intrinsic-factor antibody in black women. N Engl J Med. 1978 Mar 23. 298(12):647-50. [Medline]. [emedicine.com] Early age at onset and increased frequency of intrinsic-factor antibody in black women. N Engl J Med 1978 Mar 23; 298(12): 647-50 [Medline]. [web.archive.org] Nestor-Guillermo Progeria Syndrome @article{Cabanillas2011NstorGuillermoPS, title {N{\'e}stor-Guillermo progeria syndrome: a novel premature aging condition with early onset and chronic development caused by [semanticscholar.org] Néstor–Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations Progeria syndromes are rare disorders [scinapse.io] We define NGPS as a chronic progeria because of its slow clinical course and relatively long survival, despite its early onset. [scinapse.io] Early-Onset Familial Alzheimer Disease In general, most neurologists agree that early-onset and late-onset Alzheimer’s are essentially the same disease, apart from the differences in genetic cause and age of onset [salon.com] Those with early-onset familial AD are likely to develop AD before the age of 65 and are likely to have family members who also have early-onset AD. [ncrad.iu.edu] Types of Alzheimer’s Disease Early Onset In early onset Alzheimer’s disease, symptoms first appear before age 60. [mercyhealth.com] Gingivitis Here we present a case of cicatricial pemphigoid with onset at age 45 in a patient who manifested severe periodontal disease and showed the lesion on the mucous membranes [ncbi.nlm.nih.gov] However, in support of our hypothesis, an aggressive form of periodontitis with rapid progression and onset as early as 6 years of age is associated with DS, but not age-matched [doi.org] Since extension of the lesion into the pharynx and esophagus causes sore throat and dysphagia and progressive ocular lesions may cause blindness, early and valid diagnosis [ncbi.nlm.nih.gov] Atypical Depression Early age at onset, predominance in women, outpatient status, mild intensity, rarity of attempted suicide, nonbipolarity, nonendogenicity, and minimal psychomotor change are [ncbi.nlm.nih.gov] Hardly "atypical" in contemporary contexts, atypical depression also is common in dysthymic bipolar II disorders and is notable for its early age at onset, more chronic course [ncbi.nlm.nih.gov] Insomnia In contrast, those who have RLS that is not related to any other condition show a very slow progression of the disorder, particularly if they experience onset at an early [ninds.nih.gov] Insomnia is a condition of unsatisfactory sleep, either in terms of sleep onset, sleep maintenance or early waking. [patient.info] age; many years may pass before symptoms occur regularly. top What causes restless legs syndrome? [ninds.nih.gov] Ovarian Cyst In some cases, the onset of keratoderma is not seen until later childhood. By about 12 years of age the majority of patients have painful plantar keratoderma. [orpha.net] The many genotype-phenotype and subtype-phenotype correlations allow for early classification, prediction of clinical features and their age at onset, and optimal management [jamanetwork.com] Oral leukokeratosis occurs early, may possibly cause feeding difficulties and should be distinguished from oral candidiasis in infants. [orpha.net] Sexually Transmitted Disease Risk factors include high-risk sexual activity, young age, early onset of sexual activity, lack of condom use, having multiple sexual partners, and existing infection with [cobas.com] Distribution of pathogens (See Table I Distribution of Early Onset Pathogens Among ELBW Infants) This varies based on gestational age. [cancertherapyadvisor.com] […] known at birth including gestational age identify infants at highest risk of early-onset sepsis (EOS). [pediatrics.aappublications.org] Hypertension […] following concurrent conditions: resistant hypertension, hypokalemia (spontaneous or substantial, if diuretic induced), incidentally discovered adrenal mass, family history of early-onset [dx.doi.org] Patients with hypertension and a history of early onset hypertension and/or cerebrovascular accident at a young age may have primary aldosteronism due to glucocorticoid-remediable [doi.org] […] hypertension, or stroke at a young age ( I C-LD 2. [dx.doi.org] Alcohol Abuse "Compared with those who consumed their first alcohol drink after age 13 to15 years, early-onset drinkers appeared to be more genetically susceptible to later AD problems. [medicalnewstoday.com] "Predictors of Early Alcohol Drinking Onset." Journal of Child and Adolescent Substance Abuse 16.2 (2006). Dryden-Edwards, R., and L. Combrinck-Graham, eds. [medicinenet.com] "Age at First Alcohol Use: A Risk Factor for the Development of Alcohol Disorders." American Journal of Psychiatry 157 (2000): 745-750. Dooley, David, and Prause, Joann. [medicinenet.com] Atopy […] group, sparing the groin and axillary regions); (2) chronic or relapsing history Important features (supports the diagnosis) are as follows: Early age of onset Atopy: (1) [emedicine.medscape.com] […] cluster 3 (29%) experienced late-onset atopic troublesome asthma with decreased lung function in combination with low socioeconomic status; and cluster 4 was associated with early-onset [ncbi.nlm.nih.gov] age of onset Dry, rough skin High levels of immunoglobulin E (IgE), an antibody, in the blood Ichthyosis Hyper linear palms Keratosis pilaris Hand or foot dermatitis Cheilitis [medicinenet.com] Streptococcal Infection Two cases were the early onset type (age within 7 days) and six cases were the late onset type. Five children developed sepsis and three children developed meningitis. [ncbi.nlm.nih.gov] Type I psoriasis: early onset ( 40 years of age) and/or positive family history and/or inheritance of HLA-Cw6, -B57, or -B13. [jmg.bmj.com] Eight children developed group B streptococcal infection, and their ages ranged from 0 days to 2 months after birth. [ncbi.nlm.nih.gov] Stomatitis Age of the patient at onset Cutaneous or mucosal changes Symptoms of other organ system involvement Current medications, including herbal medications and vitamins Host factors [emedicine.medscape.com] Pain lasts 3-4 days or until a thicker fibrinous cover develops or early epithelialization occurs. Healing is complete in 7-14 days. [emedicine.medscape.com] Scoliosis Read more Early onset scoliosis Early onset scoliosis is when a curve appears between birth and age 10, or before puberty. [sauk.org.uk] When scoliosis is present prior to the age of 10, however, it is referred to as early onset scoliosis. [treatingscoliosis.com] Structural Scoliosis • Idiopathic Scoliosis Old Classification Infantile Onset 3 yrs Age Juvenile Onset 3-10 yrs Age Adolescent Onset 10 yrs Age New Classification [slideshare.net] Acne Vulgaris Data analysis was performed with the Fisher test, with a significance level of p 0.05.Results of the study: age students in the early onset of acne vulgaris appears highest [neliti.com] […] acne symptoms in females was 14.3 4.1 years. 19 Recently, studies have reported early onset of acne, at the age of 8 or 9, in line with epidemiological data, suggesting earlier [scielo.br] Acne presenting in younger children may have other ramifications, and it can be categorized by the age of onset. [dx.doi.org] Childhood Schizophrenia Early-onset schizophrenia occurs before age 18. Very early-onset schizophrenia in children younger than age 13 is extremely rare. [mayoclinic.com] With childhood schizophrenia, the early age of onset presents special challenges for diagnosis, treatment, education, and emotional and social development. [mayoclinic.com] Identifying and starting treatment for childhood schizophrenia as early as possible may significantly improve your child's long-term outcome. [mayoclinic.com] Metabolic Syndrome […] patient 2 [P2]) presented with a history of severe postnatal growth failure (adult heights: P1, -6.8 SD score; P2, -4 SD score), microcephaly, primary gonadal failure, and early-onset [ncbi.nlm.nih.gov] Alström syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, early-onset obesity, and non-insulin-dependent diabetes [ncbi.nlm.nih.gov] Severe metabolic complications, along with hepatomegaly and splenomegaly, develop at an early age. [ncbi.nlm.nih.gov] Substance Abuse The early-onset group had alcoholism earlier in life, while problems in the late-onset group begin after the age of 60. 16 Several studies have evaluated the efficacy of the [aafp.org]
