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718 Possible Causes for Early-Onset Diabetes

  • Wolcott-Rallison Syndrome

    The cardinal features of the syndrome include early-onset insulin-dependent diabetes mellitus, multiple epiphyseal dysplasia, and growth retardation.[ncbi.nlm.nih.gov] […] mellitus. ( 24710710 ) Khare S....Shah N. 2014 17 Early-onset diabetes mellitus and neurodevelopmental retardation: the first Greek case of Wolcott-Rallison syndrome. ( 24859506[malacards.org] […] mellitus. ( 24710710 ) Khare S....Shah N. 2014 18 Early-onset diabetes mellitus and neurodevelopmental retardation: the first Greek case of Wolcott-Rallison syndrome. ( 24859506[malacards.org]

  • Renal Cysts and Diabetes Syndrome

    AIMS/HYPOTHESIS: Mutations in the hepatocyte nuclear factor-1 beta ( HNF-1 beta) gene result in disorders of renal development, typically involving renal cysts and early-onset[ncbi.nlm.nih.gov] Continue » The disease is characterised by a renal developmental disorder and early-onset diabetes usually in young adults.[bioscientia-humangenetik.de] diabetes of the young - Renal dysfunction - early-onset diabetes Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare[csbg.cnb.csic.es]

  • Maturity-Onset Diabetes of the Young

    A 52-year-old woman with early-onset diabetes mellitus, severe diabetic retinopathy, and a family history of a dominant inheritance pattern was referred to our hospital.[ncbi.nlm.nih.gov] Maturity-onset diabetes of the young (MODY) is an autosomal dominant form of early onset diabetes.[ncbi.nlm.nih.gov] The identification of a mutation in glucokinase gene and transcription factor genes in patients with early-onset diabetes confirms the diagnosis of MODY and has important[ncbi.nlm.nih.gov]

  • Wolfram Syndrome

    BACKGROUND: Wolfram syndrome (WFS) is a recessive neurologic and endocrinologic degenerative disorder, and is also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes[ncbi.nlm.nih.gov] Wolfram syndrome is a rare, autosomal recessive disorder characterized by early-onset diabetes mellitus, optic atrophy and neurological and endocrinological abnormalities.[ncbi.nlm.nih.gov] Wolfram syndrome (WFS) is an autosomal recessive disorder characterized by early onset diabetes mellitus, progressive optic atrophy, sensorineural deafness and diabetes insipidus[ncbi.nlm.nih.gov]

  • Menopause

    2 diabetes in postmenopausal women.[ncbi.nlm.nih.gov] […] normal menopause, respectively, relative to those with late menopause (p trend CONCLUSIONS/INTERPRETATION: Early onset of natural menopause is an independent marker for type[ncbi.nlm.nih.gov] After adjustment for confounders, HRs for type 2 diabetes were 3.7 (95% CI 1.8, 7.5), 2.4 (95% CI 1.3, 4.3) and 1.60 (95% CI 1.0, 2.8) for women with premature, early and[ncbi.nlm.nih.gov]

  • Hypertension

    Aggressive ARB treatment of patients in the early (microalbuminuric) stages of diabetic nephropathy has a significant renoprotective effect, delaying the onset of overt (proteinuric[ncbi.nlm.nih.gov] , different rates of the development of new-onset diabetes have been reported with different BP-lowering treatment strategies. 8, 12, 21 In early trials using higher doses[dx.doi.org] BP-lowering drugs and new-onset diabetes People with hypertension experience a doubling in their lifetime risk of developing type II diabetes. 174 In several recent trials[dx.doi.org]

  • Metabolic Syndrome

    Alström syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, early-onset obesity, and non-insulin-dependent diabetes[ncbi.nlm.nih.gov] Alstrom syndrome (ALMS) is a very rare genetic autosomal recessive disease, characterized by early-onset severe abdominal obesity, impaired glucose tolerance or type 2 diabetes[ncbi.nlm.nih.gov] […] for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21–q24.[dx.doi.org]

  • Hypogonadism

    This study aims to compare the prevalence of hypogonadism between male patients with early-onset type 2 diabetes mellitus (T2DM) and late-onset type 2 diabetes.[ncbi.nlm.nih.gov] Compared with late-onset T2DM, those with early-onset T2DM had a higher proportion of new-onset diabetes, were more likely to be obese, and had worse glycemic control, lipid[ncbi.nlm.nih.gov] The mean onset age was 29.86 6.31 and 54.47 9.97 years old in the early-onset group and late-onset group, respectively.[ncbi.nlm.nih.gov]

  • Insulin Resistance

    Dominant-negative effects of a novel mutated Ins2 allele causes early-onset diabetes and severe beta-cell loss in Munich Ins2C95S mutant mice.[doi.org] Early precursors of adult-onset diabetes mellitus. Am J Epidemiol 1973 ; 97: 314 –23. 10. Barrett-Connor E..[doi.org] […] of Type 1 diabetes an average of two years in children and adults at high risk, according … Type 1 Diabetes Treatment Using New Techniques to Detect Early Signs of Type 2[dlife.com]

  • Periodontitis

    […] prevention strategies, such as lifestyle intervention, resulted in a reduction in diabetes mellitus onset and consequently, it was associated with a 47% reduction in the[doi.org] […] incidence of threatening retinopathy. 36 Recently, a 23-year follow-up of the latter study showed that early lifestyle intervention was associated with a decrease in the cumulative[doi.org] […] progression from pre-diabetes to overt diabetes mellitus and reduce the incidence of chronic complications. 35 For example, the results of a 20-year follow-up study showed that early[doi.org]

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