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47 Possible Causes for Early Onset Puberty, Increased Sweating, Lower Extremity Pain

  • Fabry Disease

    The number and size of these lesions progressively increase with age.[emedicine.medscape.com] Often patients have slight builds with characteristic coarse facial features and delayed puberty.[patient.info] […] trunk, severe pain in the extremities, corneal opacities, and vascular disease affecting the kidneys, heart, or brain[merriam-webster.com]

  • Obesity

    The administration of leptin permitted progression of appropriately timed pubertal development in the single child of appropriate age and did not cause the early onset of[doi.org] The claims most strongly affected by BMI were related to the following: lower extremity, wrist or hand, and back (body part affected); pain or inflammation, sprain or strain[ncbi.nlm.nih.gov] puberty in the younger children ( 11 ).[doi.org]

  • Osteoporosis

    If sodium intakes were also lower in developing than developed nations or urinary sodium were reduced for other reasons such as increased sweat losses, the calcium requirement[fao.org] The deficiency can be the result of late onset of puberty/getting their period, early menopause (before 40), or an absence or suppression of menstruation.[umms.org] Common complaints announced by patients are severe pain in the lower back, hips and the joints of the lower extremities with a reduced and less mobility status in general.[ncbi.nlm.nih.gov]

  • Gout

    Anointings and rubbings and p417 sweatings are necessary.[penelope.uchicago.edu] In men, uric acid levels rise at puberty, and the peak age of onset of gout in men is in the fourth to sixth decade of life.[emedicine.com] Acute gout most often presents as attacks of pain, erythema, and swelling of one or a few joints in the lower extremities.[ncbi.nlm.nih.gov]

  • Autosomal Recessive Pachydermoperiostosis 

    The presentation at a community clinic with a gradual onset of increased size of hands and feet, facial coarsening, increased sweating and seborrhea led to a referral to a[edmcasereports.com] The onset of PHO is usually before the age of 20, but its biphasic incidence is now attributed to the genetic heterogeneity, with onset of symptoms in early childhood for[jrheum.org] We report a case of a family with a variant form of primary hypertrophic osteoarthropathy (HOA) restricted to the lower extremities without digital clubbing or cutaneous changes[ncbi.nlm.nih.gov]

  • Slipped Capital Femoral Epiphysis

    Symptoms of hyperthyroidism include: chest pain increased heart rate excessive sweating heat intolerance nervousness headache tremor insomnia diarrhea vomiting weight loss[gearsteroids.buy.bushorchimp.com] Table 2 Co-morbidity Neurocognitive disorder (ADD, ADHD, Autism) 15 Thyroid insufficiency 2 Down’s syndrome 2 Other chromosome abnormalities 3 Hypopituitarism 1 Early onset[bmcmusculoskeletdisord.biomedcentral.com] Knee pain Hip, thigh or groin pain Decreased or painful hip motion Difficulty walking; limping Affected lower extremity turns outward when your child is standing How is a[childrenshospitaloakland.org]

  • Acne Vulgaris

    Sweat does not cause acne. There is, though, an increased buildup of bacteria after exercise, so it is advisable to shower.[webmd.com] onset of acne, at the age of 8 or 9, in line with epidemiological data, suggesting earlier start of puberty. 25 Table 3 shows an increase in the prevalence of inflammatory[scielo.br] Relative pain scores were evaluated using 10‐cm VAS, with 0 being ‘no pain’ and 10 being ‘extremely painful’.[doi.org]

  • Gouty Arthritis

    Anointings and rubbings and p417 sweatings are necessary.[penelope.uchicago.edu] In men, uric acid levels rise at puberty, and the peak age of onset of gout in men is in the fourth to sixth decade of life.[emedicine.com] Gouty arthritis, one of the most painful and common forms of adult arthritis, is caused by monosodium urate crystal deposits in joints, most often in the lower extremities[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Increased or decreased sweating. Nerve damage can disrupt how your sweat glands work and make it difficult for your body to control its temperature properly.[mayoclinic.org] Type 1 DM usually starts in children aged 4 years or older, appearing fairly abruptly, with the peak incidence of onset at age 11-13 years (ie, in early adolescence and puberty[emedicine.com] […] in the lower extremities because of lack of blood supply ( claudication ).[medicinenet.com]

  • Lumbar and Sacral Arthritis

    Some patients notice a mild increase or worsening of their pain for the first day or two after injection.[spinedallas.com] Low estrogen may be because of late onset of puberty/getting their period, early menopause (before 40), or an absence or suppression of menstruation.[triadspine.com] Conclusion: The SI joint is a frequent source of low back and lower extremity pain.[painteamrva.com]