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106 Possible Causes for Early Onset Puberty, Pathological Fracture, X-Ray Abnormal

  • Osteoporosis

    If the VFA results reveal suspected abnormalities, plain x-rays should be done to confirm the diagnosis.[merckmanuals.com] The end-result is a loss of bone mass and fragility that predisposes patients to falls and pathological fractures, the hallmarks of osteoporosis.[symptoma.com] The deficiency can be the result of late onset of puberty/getting their period, early menopause (before 40), or an absence or suppression of menstruation.[umms.org]

  • Ewing's Sarcoma

    Dynamic, or flexion/extension X-rays (X-rays that show the spine in motion) may be obtained to see if there is any abnormal or excessive movement or instability in the spine[columbiaspine.org] Two cycles of chemotherapy were initiated before he sustained a fall and a resultant pathological patellar fracture.[ncbi.nlm.nih.gov] Due to the prevalence of diagnosis during teenage years, a link may exist between the onset of puberty and the early stages of this disease, although no research confirms[en.wikipedia.org]

  • Primary Hyperoxaluria

    The investigation yielded the following results: normal urinalysis; renal ultrasonography showing hyperechogenic kidneys of age-compatible size; abdominal x-ray with no abnormalities[jped.com.br] Areas with high concentrations of calcium oxalate, so-called dense metaphyseal bands, are at risk for pathological fracturing.[ncbi.nlm.nih.gov] […] diabetes mellitus (82%) Childhood obesity Hypogonadism Hypothyroidism Major Hypertriglyceridaemia HypoHDLemia ALMS I gene mutation Insulin-sensitiser Insulin therapy Cystinosis early-onset[ojrd.biomedcentral.com]

  • Rib Fracture

    Plain X-rays of the skeleton in the areas of abnormality identified at bone scan, are still needed to evaluate for the exact nature of the abnormality.[radiologyassistant.nl] Buckle rib fractures can also occur.[radiopaedia.org] Includes an inability to maintain normal water balance in the body, low thyroid hormone, low growth hormone, early or late puberty, high prolactin levels and other abnormalities[rohhadassociation.com]

  • Diabetic Autonomic Neuropathy

    In these people, the unusually dense bones may be discovered by accident when an x-ray is done for another reason.[ncbi.nlm.nih.gov] Following these findings, the patient was subjected to whole body radiographic survey to rule out the presence of pathological fractures in the bones.[hindawi.com] Type 1 DM usually starts in children aged 4 years or older, appearing fairly abruptly, with the peak incidence of onset at age 11-13 years (ie, in early adolescence and puberty[emedicine.medscape.com]

  • Pulmonary Hemangioma

    In January 2003, a 73-year-old female presented with abnormal chest X-ray findings.[kjim.org] The bone is weak, and this weakness predisposes the patient to pathologic fractures.[emedicine.medscape.com] onset of puberty.[en.wikipedia.org]

  • Osteogenesis Imperfecta

    The bone scan shows abnormalities earlier than plain x-rays but does not distinguish between infection, fractures, and tumors.[msdmanuals.com] These cases present with several pathologic fractures in the body during autopsies.[symptoma.com] puberty/early adulthood Age 20 to 40s usually at birth birth corneal thinning central or paracentral inferior crescent-shaped band 1-2 mm wide generalized and slightly more[medical-dictionary.thefreedictionary.com]

  • Porphyria

    fractures Vertebral compression and collapse Osteolytic and sclerotic lesion PCT Cutaneous lesions include the following (see the Dermatology Online Atlas for images of cutaneous[web.archive.org] Clinical onset usually occurs in infancy or in early childhood, but very rare cases of onset at puberty or later have been reported. [31] Hemolysis may be a feature in homozygous[emedicine.medscape.com] Pseudoscleroderma Mutilation of facial skin and cartilage Musculoskeletal findings include the following: Resorption of distal phalanges Contractures Decreased range of motion Pathological[web.archive.org]

  • Hereditary Neonatal Hyperparathyroidism

    , such as: Elevated alkaline phosphatase, Hypophosphatemia, Hypercalciuria Shortened QT interval on electrocardiogram X-ray abnormalities, including: Brown tumors, Resorption[enotes.tripod.com] Early radiologic features include: bony demineralization, pathologic fractures of long bones and ribs, subperiosteal resorption, rib fractures and rachitic changes.[iofbonehealth.org] […] diabetes mellitus (82%) Childhood obesity Hypogonadism Hypothyroidism Major Hypertriglyceridaemia HypoHDLemia ALMS I gene mutation Insulin-sensitiser Insulin therapy Cystinosis early-onset[ojrd.biomedcentral.com]

  • Ewing Family of Tumors

    Broken bone (fracture) resulting from weakening of bone due to a tumour, this is known as a 'pathological fracture.'[web.archive.org] Due to the prevalence of diagnosis during teenage years, a link may exist between the onset of puberty and the early stages of this disease, although no research confirms[en.wikipedia.org] Imaging tests This may include one or more of the following: X-rays to image your bones and identify the presence of a tumor MRI scan to image soft tissue, organs, muscles[healthline.com]

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