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135 Possible Causes for Early Onset Puberty, Peripheral Neuropathy, X-Ray Abnormal

  • Diabetic Autonomic Neuropathy

    Type 1 DM usually starts in children aged 4 years or older, appearing fairly abruptly, with the peak incidence of onset at age 11-13 years (ie, in early adolescence and puberty[emedicine.medscape.com] In these people, the unusually dense bones may be discovered by accident when an x-ray is done for another reason.[ncbi.nlm.nih.gov] Abstract To investigate the relationship between diabetic autonomic and peripheral neuropathies, we carried out power spectral analysis (PSA) of heart rate variations and[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Type 1 DM usually starts in children aged 4 years or older, appearing fairly abruptly, with the peak incidence of onset at age 11-13 years (ie, in early adolescence and puberty[emedicine.com] We presented apical healing of the upper central incisor, retrofilled with TSC, in a diabetic patient (type 2 DM) with peripheral neuropathy.[ncbi.nlm.nih.gov] neuropathy.[ncbi.nlm.nih.gov]

  • Porphyria

    Clinical onset usually occurs in infancy or in early childhood, but very rare cases of onset at puberty or later have been reported. [31] Hemolysis may be a feature in homozygous[emedicine.medscape.com] Any part of the nervous system may be involved with autonomic and peripheral neuropathy. Peripheral neuropathy may be symmetric or asymmetric.[symptoma.com] Part 1: peripheral neuropathies, Neurological Sciences, 10.1007/s10072-019-03778-7, (2019). Maureen B.[doi.org]

  • Friedreich Ataxia

    Cases with early onset are associated with larger triplet nucleotide expansions.[symptoma.com] Evidence from X-ray fluorescence and immunohistochemical studies has highlighted an important role for glial cells; intracellular ferritin expression is abnormally high in[academic.oup.com] Peripheral neuropathy, skeletal deformities, high-arched feet, and rotation of the spine (scoliosis) also may occur. Read More[britannica.com]

  • Primary Hyperoxaluria

    […] diabetes mellitus (82%) Childhood obesity Hypogonadism Hypothyroidism Major Hypertriglyceridaemia HypoHDLemia ALMS I gene mutation Insulin-sensitiser Insulin therapy Cystinosis early-onset[ojrd.biomedcentral.com] The investigation yielded the following results: normal urinalysis; renal ultrasonography showing hyperechogenic kidneys of age-compatible size; abdominal x-ray with no abnormalities[jped.com.br] Retinal epithelium and the macula  diminished visual acuity Hypothyroidism, peripheral neuropathy, dental problems Skin manifestations Livedo reticularis, peripheral[slideshare.net]

  • Osteoporosis

    If the VFA results reveal suspected abnormalities, plain x-rays should be done to confirm the diagnosis.[merckmanuals.com] The deficiency can be the result of late onset of puberty/getting their period, early menopause (before 40), or an absence or suppression of menstruation.[umms.org] This is especially important for people who have peripheral neuropathy (see fact sheet 555 ) in their feet or legs.[aidsinfonet.org]

  • Rib Fracture

    Plain X-rays of the skeleton in the areas of abnormality identified at bone scan, are still needed to evaluate for the exact nature of the abnormality.[radiologyassistant.nl] Includes an inability to maintain normal water balance in the body, low thyroid hormone, low growth hormone, early or late puberty, high prolactin levels and other abnormalities[rohhadassociation.com] Published evidence A kinship of autonomic sensory neuropathy prevalence with reflux cough (possibly vagal) followed by peripheral sensory neuropathy was recently described[doi.org]

  • Fabry Disease

    V4-6) meeting ECG criteria for LVH. e Chest X-ray demonstrating a dual chamber secondary prevention implantable cardioverter-defibrillator (ICD) in an AFD patient presenting[doi.org] Often patients have slight builds with characteristic coarse facial features and delayed puberty.[patient.info] Neurological complications include central nervous system involvement with cerebrovascular disease, peripheral neuropathy, and autonomic dysfunction.[ncbi.nlm.nih.gov]

  • Adrenal Gland Neoplasm

    Symptoms of androgen-producing tumors in boys include the early onset of puberty.[nyulangone.org] You may have long-term side effects like pain at the site of surgery incision, numbness/tingling/pain in the hands and feet (peripheral neuropathy), difficulty concentrating[hopkinsmedicine.org]

  • Anorexia Nervosa

    […] as age 8 and as late as middle age, but its onset is most common around or just after puberty.[emilyprogram.com] neuropathy, and diffuse leukoencephalopathy on brain magnetic resonance imaging.[ncbi.nlm.nih.gov] The onset is typically at or around puberty, although anorexia can also start as early as age 8 and in middle age.[remudaranch.com]

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