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10 Possible Causes for Early Repolarization, Myoclonic Jerking, Sinus Bradycardia

  • Cocaine Abuse

    Arrhythmias: Sinus tachycardia is the most common arrhythmia and usually responds to control of agitation and IV fluids.[clinicaladvisor.com] ACLS protocols for significant tachycardias and bradycardias should be followed. NaHCO 3 has been effective in case reports of wide complex arrhythmias due to cocaine.[clinicaladvisor.com]

  • Sick Sinus Syndrome

    Syncope may be accompanied by myoclonic jerks (convulsive syncope), but postictal confusion is absent.[ncbi.nlm.nih.gov] Types of sick sinus syndrome Sinus bradycardia A normal heart rate is considered to be from 60 to 100 beats per minute.[belmarrahealth.com] The simultaneous occurrence of V596M and R16472H may increase the severity of early repolarization.[ncbi.nlm.nih.gov]

  • Syncope

    jerking is common in syncope.[emed.ie] During her hospitalization for tapering of AEDs and 24-hour EEG monitoring, the patient developed a seizure followed by sinus bradycardia and an 18-second sinus pause, resulting[ncbi.nlm.nih.gov] Why is ‘Benign’ early repolarization not a benign condition in patients with syncope? Which children with syncope should be admitted? and many more….[emergencymedicinecases.com]

  • Carotid Sinus Syncope

    Patients in whom the cardiac arrest had lasted 14 seconds had 1 or 2 generalized myoclonic jerks.[ajnr.org] Do Not Do Recommendation Do not diagnose carotid sinus syncope if carotid sinus massage causes asymptomatic transient bradycardia or hypotension.[nice.org.uk] In patients with syncope, the clinical significance of the early repolarization pattern is unknown. Recommendations for Early Repolarization Pattern 5.[ahajournals.org]

  • Wilson Disease

    jerking similar to that seen in progressive myoclonic syndrome.[web.archive.org] Most frequent findings seen were T wave abnormality in 18 patients (35.2%) followed by sinus tachycardia and sinus bradycardia in 12 and 8 patients respectively.[ncbi.nlm.nih.gov] […] lesions Abdominal imaging findings are neither sensitive nor specific Resting ECG abnormalities include left ventricular or biventricular hypertrophy, early repolarization[emedicine.com]

  • Torsades De Pointes

    Therefore, in this context long or short QT syndrome, Brugada syndrome or early repolarization syndrome were unlikely. 6 Analysis of periods of torsade de pointes in our patient[elsevier.pt] The following day, nursing staff observed repetitive, short-lived episodes of generalized mild myoclonic jerks. The patient remained conscious during these episodes.[consultant360.com] KEYWORDS: Adenosine; Arrhythmias; PSVT; QT interval; Sinus bradycardia[ncbi.nlm.nih.gov]

  • Sudden Cardiac Death

    The following points need to be considered: Prompt recognition and diagnosis (brief seizure-like activity or involuntary myoclonic jerks have been reported in approximately[cry.ie] bradycardia, and SCD from stress-induced polymorphic VT (see Figure 3 C) ( 12 ).[doi.org] Patients having major clinical events showed more frequent Brugada type patterns, early repolarization, and more diffuse multivessel coronary vasospasms.[ncbi.nlm.nih.gov]

  • Familial Progressive Cardiac Conduction Defect Type 2

    Seizures began at 21/2 years with arm stiffness, then clusters of right-sided facial twitching and weakness, then staring spells, eye twitching, and myoclonic jerks.[bcmj.org] Electrocardiogram typically shows sinus bradycardia, sinus arrest, and/or sinoatrial block.[abcam.com] Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med 2009; 361: 2529–37.[aerjournal.com]

  • SHORT Syndrome

    High prevalence of early repolarization in short QT syndrome. Heart Rhythm 2010;7:647-52.[acc.org] Myoclonic seizures (brief shock-like jerks of a muscle or group of muscles) appear between 1 and 5 years in 85% of children with Dravet syndrome.[epilepsy.com] In addition, they can reduce wrong diagnosis in SQT patients with sinus bradycardia since it is known that Bazett formula overcorrects the QT interval at slow heart rates.[escardio.org]

  • Dofetilide

    jerks, sleep disorder, anxiety, syncope, head injuries, or a family history of seizures Have any serious or active medical or psychiatric illness (including depression) which[clinicaltrials.gov] Dofetilide does not exacerbate bradycardia and has been shown to be safe for use in patients with left ventricular dysfunction. 4, 5 The 2006 and 2011 Maintenance of Sinus[innovationsincrm.com] […] afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg[caymanchem.com]

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