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391 Possible Causes for Easy Bruising, Fatigue, Lactate Dehydrogenase Increased, Paraparesis

  • Acute Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[ncbi.nlm.nih.gov] Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[nlm.nih.gov] Abstract We present the case of a 16-year-old boy who presented with fatigue, polyuria, and polydipsia while on chemotherapy for his relapsed acute lymphoblastic leukemia[ncbi.nlm.nih.gov] bruising or bleeding Petechiae (flat, pinpoint spots under the skin caused by bleeding) Shortness of breath Weight loss Loss of appetite Bone or joint pain Stomach pain Pain[uvahealth.com]

  • Multiple Myeloma

    Also, reflecting this aggressive clinical presentation, a higher proportion of patients with pPCL have significant leukocytosis, elevated lactate dehydrogenase (LDH) and β2[doi.org] bruising or bleeding – due to low platelet numbers Bleeding from the nose or gums Repeated infections or infections that are hard to get rid of Thirst, nausea, vomiting or[betterhealth.vic.gov.au] She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure.[ncbi.nlm.nih.gov] We describe a man recently diagnosed with multiple myeloma who presented with progressive spastic paraparesis, encephalopathy and multifocal MRI lesions with haemorrhage.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The latter was associated more frequently with anaemia, thrombocytopenia, peripheral blood blasts and increased lactate dehydrogenase levels.[ncbi.nlm.nih.gov] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Lactate Dehydrogenase (LDH) Anemia Splenomegaly What Other Diseases Should Be Considered and How Do I Distinguish Between Them?[clinicaladvisor.com]

  • Familial Myelofibrosis

    Because platelets play an essential role in homeostasis, thrombocytopenia results in easy bruising and a propensity to bleed.[symptoma.com] Anemia is one of the hallmarks of pancytopenia and is associated with fatigue, pallor, and cyanosis. Children may also be tachypneic due to hypoxia.[symptoma.com] Lack of red blood cells manifests in fatigue, pallor, and cyanosis, while white blood cell deficiencies result in an increased susceptibility to infection.[symptoma.com]

  • Acute Myelocytic Leukemia

    Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[medlineplus.gov] Symptoms include anemia, fatigue, weight loss, easy bruising, thrombocytopenia, and granulocytopenia that leads to persistent bacterial infections.[medical-dictionary.thefreedictionary.com] Symptoms include: Unexplained and persistent fever Marked fatigue and weakness Unexpected weight loss with poor appetite Easy bruising or bleeding.[drugs.com] […] chronic myeloid leukemia . chronic lymphocytic leukemia chronic leukemia of the lymphoblastic type, a common form mainly seen in the elderly; symptoms include lymphadenopathy, fatigue[medical-dictionary.thefreedictionary.com]

  • Non-Hodgkin Lymphoma

    Most of the aggressive lymphomas present with a rapidly growing tumor mass, fever, night sweats, weight loss, and increased levels of serum lactate dehydrogenase and uric[symptoma.com] bruising or bleeding bleeding under the skin shortness of breath weight loss or loss of appetite pain in the bones or stomach pain or a feeling of fullness below the ribs[icd9data.com] The patient was a 77-year-old man with history of symptoms of partial bowel obstruction, intermittent right iliac fossa pain, loss of weight, vomiting and fatigue.[ncbi.nlm.nih.gov] One indicator of the potential for tumor lysis syndrome is an elevated plasma lactate dehydrogenase level or hyperuricemia at the time of diagnosis.[emedicine.medscape.com]

  • Viral Hepatitis

    This is followed by the prodromal period, which is characterized by acute manifestations such as fatigue, malaise, fever, anorexia, nausea, emesis, abdominal pain, urticaria[symptoma.com] Neurologic examination showed flaccid paraparesis, areflexia in all extremities and limitation on the straight leg raising test.[ncbi.nlm.nih.gov] Symptoms of acute (newly acquired) hepatitis include: fever, fatigue, loss of appetite, nausea, vomiting, abdominal/stomach pain, dark urine, clay-colored feces, joint pain[dph.georgia.gov] The most frequently reported symptom was fatigue (73.7%), and the most common complications were cholecystitis (0.4%) and fulminant hepatitis (0.4%).[ncbi.nlm.nih.gov]

  • Rocky Mountain Spotted Fever

    The illness begins with headache , fever, and chills, soon followed by pains in the bones and joints, weakness, and fatigue.[britannica.com] Long-term neurologic sequelae of RMSF include cognitive impairment; paraparesis; hearing loss; blindness; peripheral neuropathy; bowel and bladder incontinence; cerebellar[doi.org] "He was fatigued, he had a headache and he was very nauseated with a sore throat." One doctor thought Jaden had strep throat and prescribed him a Z-pack.[wymt.com] Headache Rash—begins as small, flat pink spots on wrists and ankles Nausea and vomiting Abdominal pain Muscle or joint pain Lack of appetite Red eyes Light hurting the eyes Fatigue[cancercarewny.com]

  • Hairy Cell Leukemia

    Lactate dehydrogenase (LDH) is usually normal.[clinicaladvisor.com] A shortage of blood platelets may lead to easy bruising or bleeding.[cancercenter.com] During interferon-α therapy she developed multiple subcutaneous swellings, accompanied by fever and fatigue.[ncbi.nlm.nih.gov] Intriguingly, HTLV-1 also is the causative agent of a distinct neurological disorder termed HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) (for review[doi.org]

  • Chronic Myeloid Leukemia

    […] serum lactate dehydrogenase level, anemia, and palpable splenomegaly.[doi.org] It can lead to easy bruising or bleeding, with frequent or severe nosebleeds and bleeding gums. Some patients with CML actually have too many platelets (thrombocytosis).[cancer.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] There is a lack of red blood cells, leading to anemia, and platelets, leading to bleeding tendencies and easy bruising.[news-medical.net]

    Missing: Paraparesis

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