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10 Possible Causes for Easy Bruising, Intermittent Jaundice, Uric Acid Increased

  • Hereditary Spherocytosis

    Abstract Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia due to defect in RBC membrane protein that commonly presents with intermittent jaundice[ncbi.nlm.nih.gov] Dubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia.[ncbi.nlm.nih.gov] Fatigue is associated with intermittent jaundice.[explainmedicine.com]

  • Primary Biliary Cirrhosis

    Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[medicinenet.com] Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.[ncbi.nlm.nih.gov] Reddy AN, Grosberg SJ, Wapnick S: Intermittent cholestatic jaundice and nonmetastatic prostatic carcinoma. Arch Intern Med 1977;137:1616–1618.[clevelandclinicmeded.com]

  • Congenital Liver Cirrhosis

    acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[clevelandclinicmeded.com] Cirrhosis can lead to Easy bruising or bleeding, or nosebleeds Swelling of the abdomen or legs Extra sensitivity to medicines High blood pressure in the vein entering the[icdlist.com] He had intermittent high grade fever with dry cough and respiratory distress for 4 days duration.[indianpediatrics.net]

  • Tyrosinemia

    […] and frequent bruising Difficulty in gaining weight Abdominal swelling and bloating Increased tendencies to bleed, especially nosebleeds The common symptoms of this condition[hxbenefit.com] The tubular handling of phosphorus, uric acid, beta 2-microglobulin, and amino acids was disturbed. Low urinary osmolality was also seen.[ncbi.nlm.nih.gov] The acute onset may be dramatic, with hepatomegaly, jaundice, epistaxis, melaena, purpuric lesions, marked oedema, and the distinctive cabbage-like odour.[patient.info]

  • Rifampin

    ., confusion, unusual behavior), unusual tiredness, easy bruising/bleeding, small red spots on the skin, joint pain /swelling.[webmd.com] Effects on lab test results • May increase ALT, AST, alkaline phosphatase, bilirubin, and uric acid levels. • May increase eosinophil count.[glowm.com] Urogenital: Hemoglobinuria, hematuria, acute renal failure, light-chain proteinuria, menstrual disorders, hepatorenal syndrome, (with intermittent therapy).[robholland.com]

  • Ethambutol

    Tell patient to immediately report easy bruising or bleeding, respiratory problems, or signs and symptoms of hypersensitivity reactions. • Advise patient to report vision[medical-dictionary.thefreedictionary.com] A trial of intermittent rifampin and ethambutol in retreatment regimens. Scand J Respir Dis Suppl 1973; 84: 132-5.[livertox.nih.gov] bruising or bleeding ( nosebleeds, bleeding gums); chest pain or shortness of breath with mild exertion; little or no urinating; liver problems--upper stomach pain, dark[drugs.com]

  • Liver Dysfunction

    History A man in his eighth decade presented to his primary doctor three weeks prior to admission with easy bruising.[thoracic.org] acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[clevelandclinicmeded.com] The symptoms of jaundice may be unsettling, but they are intermittent and nothing to worry about, and long-term monitoring is not typically needed.[medicalnewstoday.com]

  • Methyldopa

    […] of breath (even with mild exertion), swelling, rapid weight gain; uncontrolled muscle movements; unusual thoughts or behavior; numbness, tingling, weakness; chest pain; easy[peacehealth.org] Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, bilirubin, blood urea nitrogen, creatinine, potassium, prolactin, sodium, uric acid: increased[medical-dictionary.thefreedictionary.com] A 55 year old woman had been treated for hypertension intermittently with methyldopa in the past and then developed jaundice and fatigue 7 days after it was restarted.[livertox.nih.gov]

  • Daunorubicin

    bruising, unusual bleeding (nose, mouth, vagina, or rectum); nausea , upper stomach pain , itching, loss of appetite, dark urine, clay-colored stools , jaundice (yellowing[emedicinehealth.com] ., increased uric acid). SIDE EFFECTS: See also Warning section. Nausea, vomiting, constipation, diarrhea, and loss of appetite may occur.[medicinenet.com] There is initial elevation of serum bile acids, followed by cholestatic jaundice which generally spontaneously resolves after periods of weeks to months.[genecards.org]

  • Antitubercular Agent

    […] in blood in about 50% of patients caused by decreased renal excretion of uric acid.[cyto.purdue.edu] bruising or bleeding Bloody nose Dizziness It’s important to take every dose of your antibiotics.[webmd.com] Urogenital: Hemoglobinuria, hematuria, acute renal failure, light-chain proteinuria, menstrual disorders, hepatorenal syndrome, (with intermittent therapy).[robholland.com]

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