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232 Possible Causes for Easy Bruising, Macrocytic Anemia

  • Myelodysplasia

    If you have symptoms, they may include Shortness of breath Weakness or feeling tired Skin that is paler than usual Easy bruising or bleeding Pinpoint spots under the skin[medlineplus.gov] Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] The resulting deficiencies of platelets and red and white blood cells cause anemia, susceptibility to infections, and easy bruising and bleeding.[clinicaltrials.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Symptoms Symptoms may include: Abdominal pain Back pain Blood clots , may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[mountsinai.org] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] bruising Coughing up blood Impotence Seizures Blood clots PNH is not inherited.[medicinenet.com]

  • Vitamin B12 Deficiency

    The symptoms of B12 deficiency include tiredness, light-headedness , rapid heart rate , easy bruising and bleeding, weight loss, bowel upset and sore tongue.[healthdirect.gov.au] Megaloblastic anemias are a subgroup of macrocytic anemias, in which distinctive morphologic abnormalities occur in red cell precursors in bone marrow, namely megaloblastic[ncbi.nlm.nih.gov] […] depression Psychosis and hallucinations in advanced stages of deficiency Weight loss and stomach upset Rapid heartbeat and breathing Pale skin Swollen and inflamed tongue Easy[stylecraze.com]

  • Chronic Alcoholism

    […] of Alcohol Abuse Chronic alcohol abuse and dependence can damage all organ systems , including: Blood-forming system —resulting in anemia (low red blood cell count) and easy[healthcommunities.com] Macrocytosis with an MCV 100 fL reflects the direct effect of alcohol on bone marrow as well as macrocytic anemia resulting from folate deficiency, which is common among undernourished[merckmanuals.com] Other diseases include scurvy , resulting from vitamin C deficiency; hypochromic macrocytic anemia, caused by folate deficiency, vitamin B 12 deficiency, or certain chemotherapeutic[britannica.com]

  • Severe Aplastic Anemia

    These include fatigue, shortness of breath, fever, recurrent infections, easy bruising or unusual bleeding.[leukemiabmtprogram.org] If cell size is much smaller than normal, it is known as microcytic anemia. If it is much bigger than normal, then it is macrocytic anemia.[labtestsonline.org] Platelets are responsible for normal blood clotting and low numbers can result in easy bruising and bleeding which can be deadly.[clinicaltrials.gov]

  • Tropical Sprue

    Patients with tropical sprue typically present with macrocytic anemia due to malabsorption of folate and/or vitamin B(12).[ncbi.nlm.nih.gov] Keywords Main Side Effect Main Drug Interaction Macrocytic Anemia Tropical Sprue Celiac Sprue These keywords were added by machine and not by the authors.[link.springer.com] Past studies have indicated a megaloblastic macrocytic anemia, steatorrhea, impaired absorption of glucose, and abnormal x-ray patterns of the small bowel in untreated patients[jamanetwork.com]

  • Promyelocytic Leukemia

    A 56-year-old man presented to the ED of an outside hospital with 2 days of bleeding gums and easy bruising.[ncbi.nlm.nih.gov] The peripheral smear showed normochromic, macrocytic anemia (Hgb 9.2 g/dL, MCHC 32.8%, MCV 117 fL) and leukopenia (white blood cells [WBC] 3200/mL).[gotoper.com] Easy bruising or hemorrhagic diathesis (epistaxis, gums bleeding, hematuria, petechiae, metroragia) are frequently observed.[orpha.net]

  • Blind Loop Syndrome

    Vitamin K deficiency causing easy bruising and spontaneous bleeding. Aetiology Surgery - eg, Billroth's operation II, Roux-en-Y procedure, gastric bypass for obesity.[patient.info] Vitamin B12 deficiency may cause macrocytic anemia in which the average size of erythrocytes is larger than normal.[natural-homeremedies.org] […] with weakness and paleness [1] Impaired vitamin B12 and folate absorption resulting in macrocytic anemia and neuropathy with paleness, tingling or numbness [1,4] Impaired[nutrientsreview.com]

  • Waldenstrom Macroglobulinemia

    The covered platelet cells may not work right, resulting in bleeding and easy bruising. Every year, there are five new cases of macroglobulinemia per 1,000,000 people.[uihc.org] Peripheral blood smear was suggestive of macrocytic anemia with thrombocytopenia and few plasmacytoid lymphocytes.[pancreas.imedpub.com] Codes C88.0 Waldenstrom's macroglobulinemia Corresponding ICD-10-CM Codes (U.S. only) C88.0 Waldenstrom's macroglobulinemia (effective October 01, 2015) Signs and Symptoms Easy[seer.cancer.gov]

  • Essential Thrombocythemia

    About one-third of patients with ET will demonstrate no symptoms at all, but many will experience easy bruising or bleeding with little or no injury.[uihc.org] , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] Symptoms include dizziness, easy bruising, headache, bloody stools, numbness of the hands or feet, ulcers on the toes or fingers, nosebleeds, prolonged bleeding after surgery[amarillo.com]

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