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442 Possible Causes for Easy Bruising, Petechiae, Splenomegaly

  • Thrombocytopenia

    It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues A condition in which there is an abnormally small number[icd9data.com] We herein describe a case of nephrotic syndrome with thrombocytopenia, lymphadenopathy, systemic inflammation, splenomegaly, kidney enlargement, and progressive renal insufficiency[ncbi.nlm.nih.gov] Larger than petechiae, ecchymoses are purple, blue or yellow-green areas of skin that vary in size and shape.[en.wikipedia.org]

  • Leukemia

    Acute leukemia usually develops quickly and tends to cause fatigue, easy bruising, and frequent infections.[uabmedicine.org] Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] These were petechiae/purpura (category derived from ‘petechiae’, ‘purpura’ and ‘petechiae/purpura’), mucosal bleeding (including ‘mucosal bleeding’ and ‘bleeding gums’), anorexia[doi.org]

  • Immune Thrombocytopenic Purpura

    An 11-year-old boy presented with epistaxis, petechial hemorrhages, easy bruising, and purpuric rash.[ncbi.nlm.nih.gov] Clinical examination revealed mucosal hemorrhages and splenomegaly.[ncbi.nlm.nih.gov] Abstract In this retrospective cohort study conducted in 63 children with idiopathic thrombocytopenic purpura (ITP) in China; petechiae, bruises and bleeding were the major[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    Most common in chronic myelogenous leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to[emedicine.com] CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Both patients were suffering from thrombocytopenia and splenomegaly and underwent splenectomy. The weight of the spleen specimens was more than 2000 g.[ncbi.nlm.nih.gov]

  • Myelodysplasia

    If you have symptoms, they may include Shortness of breath Weakness or feeling tired Skin that is paler than usual Easy bruising or bleeding Pinpoint spots under the skin[medlineplus.gov] Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] ., bruising and/or petechiae) may cause patient distress.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[nlm.nih.gov] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Thrombocytopenia often causes petechiae on the lower limbs. DIC may aggravate the situation and cause larger lesions.[patient.info]

  • Primary Myelofibrosis

    Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net]

  • Acute Lymphoblastic Leukemia Type L1

    Symptoms of ALL include: Frequent infections Fever Easy bruising Bleeding that is hard to stop Flat, dark-red skin spots (petechiae) due to bleeding under the skin Pain in[stjude.org] The child redeveloped splenomegaly and fever, and then suffered an acute decompensation with hypoxemia, tachypnea, splenomegaly, and cardiac gallop.[ncbi.nlm.nih.gov] Thrombocytopenia manifests itself as bleeding, bruising and, in severe cases, petechiae.[symptoma.com]

  • Chronic Myeloid Leukemia

    It can lead to easy bruising or bleeding, with frequent or severe nosebleeds and bleeding gums. Some patients with CML actually have too many platelets (thrombocytosis).[cancer.org] Three of 4 TKI-treated patients did not reach complete hematologic response due to the persistence of thrombocytosis and/or splenomegaly.[ncbi.nlm.nih.gov] […] include: Bruising Excessive sweating (night sweats) Fatigue Fever Pressure under the lower left ribs from a swollen spleen Rash -- small pinpoint red marks on the skin ( petechiae[medlineplus.gov]

  • Chronic Lymphocytic Leukemia

    Eastern European Jews Exposure to Agent Orange Symptoms Symptoms include: Painless swelling in the neck, underarms, stomach or groin Tiredness Paleness (a sign of anemia) Easy[uvahealth.com] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] The most common treatment-related AEs (reported in at least 5 percent of patients) were headache (20 percent), an increased tendency to bruise (12 percent) and petechiae ([curetoday.com]

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