Ecchymosis: Causes & Reasons

Possible Causes for Ecchymosis

The medicolegal examination concluded that the appearance of the lesion was only mildly suggestive of an ecchymosis. [ncbi.nlm.nih.gov]

Extensive bilateral periorbital ecchymosis was documented with bilateral subconjunctival haemorrhage with no discharge (Figure 1B). [ncbi.nlm.nih.gov]

They deserve to be widely known because they mandate rapid medical management and because they are one of the only differential diagnoses of ecchymosis, especially in children [ncbi.nlm.nih.gov]

Acquired Hemophilia

After 10 weeks, he developed an ecchymosis of the right upper extremity, in the absence of past or family history of bleeding disorder. [ncbi.nlm.nih.gov]

The patient manifested spontaneous ecchymosis (Fig. 1–3). [termedia.pl]

Five months after delivery, the patient started noticing multiple ecchymosis, which started from the buttock with extension to the lower extremities, variable in size from [jahjournal.org]

Acquired Hemophilia A

A 69-year-old woman with essential thrombocythemia (ET) developed giant ecchymosis, and she was admitted to hospital. [ncbi.nlm.nih.gov]

The most common hemorrhagic symptoms were hematoma 21 (33.33%), ecchymosis 16 (25.39%), hemarthrosis 8 (12.69%), hematuria 6 (9.52%), menorrhagia 4 (6.34%), compartment syndrome [ncbi.nlm.nih.gov]

Presentation: A 73 year old female with borderline diabetes mellitus and hypertension presented to the emergency department with the sudden onset of nontraumatic swelling, pain and ecchymosis [shmabstracts.com]

Familial Myelofibrosis

Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy [monarchinitiative.org]

Clinical manifestations depend on the type of blood cell(s) affected and may include severe anemia, pallor, petechiae, ecchymosis, bleeding, thrombosis, pancytopenia, pruritus [orpha.net]

Ehlers-Danlos Syndrome Type 4

Physical examination showed large tense swelling in the antecubital fossa with ecchymosis. [omicsonline.org]

Anomalies of the skin render EDS4 patients prone to ecchymosis. Wound healing is delayed. [symptoma.com]

Recurrent temporomandibular joint subluxation and facial ecchymosis leading to diagnosis of Ehlers-Danlos syndrome. J Oral Maxillofac Surg 1990; 48(6):641-7. 24. [cda-adc.ca]

Primary Myelofibrosis

Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy [orpha.net]

Clinical manifestations depend on the type of blood cell(s) affected and may include severe anemia, pallor, petechiae, ecchymosis, bleeding, thrombosis, pancytopenia, pruritus [orpha.net]

Chronic Immune Thrombocytopenic Purpura

The only complication was extensive superficial ecchymosis on the patient's forearm from antiplatelet use, which resolved spontaneously. [casereports.bmj.com]

[…] coumarin-induced skin necrosis (a complication of anticoagulant treatment with medicines such as warfarin, causing skin death sl Anakonde so stroji za ubijanje en urticaria, psoriasis, ecchymosis [sl.glosbe.com]

>=4% of patients in the splenectomized and non-splenectomized groups, respectively, included mouth hemorrhage (4% and 1%), epistaxis (14% and 6%), petechiae (8% and 2%), ecchymosis [novartis.com]

Acute Promyelocytic Leukemia

The bleeding can manifest itself as petechiae (little bleeding spots in the skin or elsewhere), small ecchymosis ( bruises ), epistaxis (nose bleeds), bleeding in the mouth [medicinenet.com]

The bleeding can manifest itself as petechiae (little bleeding spots in the skin or elsewhere), small ecchymosis (bruises), epistaxis (nose bleeds), bleeding in the mouth, [medicinenet.com]

He was slightly pale and had a gingival hemorrhage, ecchymosis of the left thigh and hepatomegaly. [scielo.br]

Myeloproliferative Disease

[…] infarction and perisplenitis Clinical symptoms can include the following: Pallor (except in patients with polycythemia vera) Plethora secondary to polycythemia Petechiae and/or ecchymosis [emedicine.com]

[…] patients with myeloproliferative disease may include the following: Pallor, except in patients with polycythemia vera Plethora secondary to polycythemia Petechiae and/or ecchymosis [emedicine.medscape.com]

Bernard-Soulier Syndrome

Bernard-Soulier syndrome often presents early with bleeding symptoms, such as epistaxis, ecchymosis, menometrorrhagia, and gingival or gastrointestinal bleeding. [ncbi.nlm.nih.gov]

A 9-year-old girl was admitted because of diffuse ecchymosis, progressive asthenia, pallor, and fever occurring over the course of 2 weeks. [ashpublications.org]

There may be recurrent epistaxis, gingival hemorrhage, ecchymosis, easy formation of hematoma, purpura and petechiae. [oldfiles.bjorl.org]

Hereditary Factor XIIIA Deficiency

Autosomal recessive inheritance 0000007 Bruising susceptibility Bruise easily Easy bruisability Easy bruising [ more ] 0000978 Congenital onset Symptoms present at birth 0003577 Ecchymosis [rarediseases.info.nih.gov]

Amyloidosis

Although rare, cutaneous manifestations may be the first clinical sign of the disease and usually present as hemorrhagic lesions, such as purpura, petechiae, and ecchymosis [ncbi.nlm.nih.gov]

Periorbital ecchymosis. B. Perimumbilical purpuric macules. Source: Own elaboration based on the data obtained in the study. [scielo.org.co]

Hepatomegaly, nephrotic syndrome, macroglossia, orthostatic hypotension, ecchymosis, and autonomic and peripheral neuropathy can be present. [ncbi.nlm.nih.gov]

Glanzmann Thrombasthenia

Patients typically present in early childhood with moderate to severe mucocutaneous bleeding, including menorrhagia, epistaxis, gingival bleeding, GI hemorrhage, and ecchymosis [clinicaladvisor.com]

Upon physical exam in the clinic, mild effusion of the right knee was noted with no ecchymosis, and laxity tests and meniscal exams were negative. [opnews.com]

Dengue Hemorrhagic Fever

He was febrile with small ecchymosis on arms. Pulse 120/m, respiratory rate 34/m ,BP 98/60 mm Hg. Crackles heard bilaterally. [erj.ersjournals.com]

Acute Symptoms of Dengue Haemorrhagic Fever • Ecchymosis - Skin discolouration due to internal rupture of blood vessels • Generalised Rashes. • Petechiae – Red spots on the [onlymyhealth.com]

bruising - Frequent vomiting with or without blood - Black stools, like coal tar - Excessive thirst (dry mouth) - Pale, cold skin - Restlessness, or sleepiness Dengue shock [denguevirusnet.com]

Pancreatitis

[…] and edema in the subcutaneous tissue around the umbilicus) and Grey Turner sign (ecchymosis of the flank). [aafp.org]

Pandiaraja's sign- ecchymosis of right axilla[3][4] Complications[edit] Locoregional complications include pancreatic pseudocyst (Most common, occurring in up to 25% of all [en.wikipedia.org]

[…] findings are abnormal (positive likelihood ratio [LR+] = 3.2; negative likelihood ratio [LR–] = 0.8). 9 Two physical signs associated with pancreatitis are Cullen sign (ecchymosis [aafp.org]

Acquired Coagulation Factor Deficiency

The common manifestations of late HDN reported are evidence of intracranial hemorr-hage, deep ecchymosis, bleeding from GI tract and/or bleeding from mucus membrane, skin [indianpediatrics.net]

Hemophilia

The most frequent clinical manifestations were hemarthrosis (94.4%), muscle hematomas (80.6%) and ecchymosis (77.8%). [scielo.org.co]

Primary Hemostasis –> Platelet aggregation forms an initial plug (immediate) –> Deficiencies tend to cause superficial bleeds (i.e petechiae, ecchymosis, & purpura) Secondary [rebelem.com]

The following bleeding symptoms are associated with hemophilia: Excessive bleeding following minor injuries (e.g. skin cut) Large skin bruises from bleeding within the skin [innerbody.com]

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Physical examination revealed ecchymosis in upper limbs. [cureus.com]

[…] and night sweats due to an elevated basal level of metabolism.[4] Some (<10%) are diagnosed during the accelerated stage which most often presents bleeding, petechiae and ecchymosis [en.wikipedia.org]

Myelodysplasia

[…] chest pain[6] Neutropenia (low neutrophil count) – increased susceptibility to infection[7] Thrombocytopenia (low platelet count) – increased susceptibility to bleeding and ecchymosis [en.wikipedia.org]

Acute Myeloid Leukemia

Skin Findings in the skin include the presence of petechiae ecchymosis due to thrombocytopenia and pallor due to anemia. It can result in leukocytoclastic vasculitis. [lecturio.com]

Physical Examination Ecchymosis and oozing from IV sites (DIC, possible acute promyelocytic leukemia) Fever and tachycardia (signs of infection) Papilledema, retinal infiltrates [slideshare.net]

bruising easily slurred speech swollen liver swollen lymph nodes (glands) swollen spleen unexplained regular bleeding, of perhaps the nose or gums unexplained weight loss [medicalnewstoday.com]

Hereditary Factor X Deficiency

Decreased Quick percentage, acquired factor X deficiency, haemarthrosis and ecchymosis ; amyloidosis. Ther Umsch 1999; 56(9):523-5. 7. Kouides PA, Kulzer L. [ayubmed.edu.pk]

Thrombocytopathy

Physical exam may show areas of easy bruising, purpuric spots, petechiae, ecchymosis, hemarthrosis, and enlarged spleen due to sequestering of platelets. [mhmedical.com]

This type of bleeding observed small hemorrhages in the form of petechiae or ecchymosis, as in bleeding from the nose, gums, stomach and uterine bleeding. [noillen.bitballoon.com]

The main symptom of the pathology is expressed and recurrent hemorrhagic syndrome, which is manifested by the presence on the body and limbs of the child of petechial or ecchymosis [brulanta.com]

Chronic Myeloid Leukemia

In accelerated phase and blast crisis, the patient presents like acute leukemia with fever, bleeding, petechiae, ecchymosis and pallor due to overexpansion of bone marrow [lecturio.com]

[…] fever and night sweats due to an elevated basal level of metabolism.Some (<10%) are diagnosed during the accelerated stage which most often presents bleeding, petechiae and ecchymosis [en.wikipedia.org]

Essential Thrombocythemia

A 69-year-old woman with essential thrombocythemia (ET) developed giant ecchymosis, and she was admitted to hospital. [ncbi.nlm.nih.gov]

When symptoms do appear, they can include skin bruising or bleeding from various areas such as the nose, mouth, and gums, or the stomach and intestinal tract. [my.clevelandclinic.org]

If you do have symptoms, they can include: Skin bruising. Bleeding from places like the nose, mouth and gums. Bleeding in the stomach or intestinal tract.. [my.clevelandclinic.org]

Polycythemia Vera

Weakness, fatigue, headache, blood clotting, vertigo, tinnitus, irritability, dyspnea, visual disturbances, flushing of face, redness, or ruddy cyanosis, pruritus, ecchymosis [medical-dictionary.thefreedictionary.com]

Paroxysmal Nocturnal Hemoglobinuria

Bruise easily Men may have trouble getting or keeping an erection Continued The symptoms of blood clots depend on where the clot happens: Skin : Red, painful, or swollen [webmd.com]

[…] and anemia may make you: Feel tired and weak Have headaches Feel short of breath Have an irregular heartbeat Have belly pain Have trouble swallowing Have pale or yellowish skin [webmd.com]

Blast Phase of Chronic Myeloid Leukemia

It may also present with mild fever and night sweats due to an elevated basal level of metabolism. [4] Some ( petechiae and ecchymosis. [4] In these patients fevers are most [en.wikipedia.org]

Platelet Storage Pool Deficiency

Delta-Storage Pool Deficiency is characterized by mucocutaneous bleeding (particularly epistaxis), surgical bleeding, and ecchymosis. [clinicaladvisor.com]

Pertinent examination findings include petechiae and ecchymosis. These teenagers should undergo platelet testing concurrent with VWF assays. [ehoonline.biomedcentral.com]

Ecchymosis - a black-and-blue discolored area of the skin caused by bleeding into the subcutaneous tissue. A bruise. [glanzmanns.com]

Severe Aplastic Anemia

Other symptoms include: Weakness Shortness of breath and chest pain Dizziness, especially after standing up from a sitting or lying position Headaches Pale skin Bruising or [everydayhealth.com]

Nelson Syndrome

[…] described as 'moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin [radiopaedia.org]

bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis hypertension hyperglycemia and development of overt diabetes mellitus immunosuppression [radiopaedia.org]