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104 Possible Causes for Ecchymosis, Hypercellular Bone Marrow

  • Chronic Myeloid Leukemia

    In accelerated phase and blast crisis, the patient presents like acute leukemia with fever, bleeding, petechiae, ecchymosis and pallor due to overexpansion of bone marrow[lecturio.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] It may also present with mild fever and night sweats due to an elevated basal level of metabolism. [4] Some ( petechiae and ecchymosis . [4] In these patients fevers are most[en.wikipedia.org]

  • Myeloproliferative Disease

    […] infarction and perisplenitis Clinical symptoms can include the following: Pallor (except in patients with polycythemia vera) Plethora secondary to polycythemia Petechiae and/or ecchymosis[emedicine.medscape.com] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] […] patients with myeloproliferative disease may include the following: Pallor, except in patients with polycythemia vera Plethora secondary to polycythemia Petechiae and/or ecchymosis[emedicine.medscape.com]

  • Polycythemia Vera

    Weakness, fatigue, headache, blood clotting, vertigo, tinnitus, irritability, dyspnea, visual disturbances, flushing of face, redness, or ruddy cyanosis, pruritus, ecchymosis[medical-dictionary.thefreedictionary.com] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Signs of bleeding may include presence of petechiae, ecchymosis and swollen gums.[symptoma.com] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[emedicine.medscape.com] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[medbullets.com] The degree of marrow failure may vary from severe aplastic anemia to a decrease in the number of hematopoietic stem cells.[emedicine.medscape.com]

  • Essential Thrombocythemia

    A 69-year-old woman with essential thrombocythemia (ET) developed giant ecchymosis, and she was admitted to hospital.[ncbi.nlm.nih.gov] ET is usually characterized by a hypercellular bone marrow, including increased numbers of megakaryocytes.[labce.com] Platelets aggregation studies • impaired platelet aggregation • Spontaneous platelets aggregation Bone marrow biopsy • Hypercellular marrow (90%) • Megakaryocytic hyperplasia[slideshare.net]

  • Passovoy Factor Defect

    [from OMIM ] Bruising susceptibility MedGen UID: 140849 • Concept ID: C0423798 • Finding An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood[ncbi.nlm.nih.gov] The combination of pancytopenia and hypercellular bone marrow suggested that this patient had myelodysplastic syndrome (MDS).[vdocuments.site] The probands older son, aged 7, by her first marriage,had axillary ecchymosis as an infant from the age of3 weeks as a result of being picked up. He bruiseseasily.[documents.tips]

  • Hairy Cell Leukemia

    In addition, patients may present with cutaneous manifestations, such as herpes zoster, cellulitis, abscess, pyoderma, dermatophytosis, leukemia cutis, ecchymosis, and purpura[hematologyandoncology.net] Fig. 2: TRAP ; Fig. 3: hypercellular bone marrow with monotonous "fried egg" lymphocytes with abundant cytoplasm Cytology description Small / intermediate size cells with[pathologyoutlines.com] Bone marrow aspiration showed hypercellular marrow with cells characterized by irregular windblown-appearing cell borders with pseudopod-like projections.[ncbi.nlm.nih.gov]

  • Acute Undifferentiated Leukemia

    Bleeding may be from the skin, gastrointestinal tract and reproductive system, evidenced by epistaxis, petechiae, ecchymosis, hematuria, and abnormal uterine bleeding.[symptoma.com] 7 Year Member Joined: Feb 16, 2008 Messages: 47 Likes Received: 0 This was from a practice teaching case and I'm not sure I agree...Hypercellular bone marrow with 94% blasts[forums.studentdoctor.net]

  • Amegakaryocytic Thrombocytopenia

    There was ecchymosis over the abdomen and thigh, largest measuring 3 cms over the abdomen. (Figure 1 & 2) Vitals - Pulse was 90 /min, good volume.[jebmh.com] […] by normal-to-hypercellular bone marrow.[jahjournal.org] […] megakaryocytes in an otherwise normal bone marrow. [1] It needs to be differentiated from the more common disorder, immune thrombocytopenic purpura (ITP), which is characterized[jahjournal.org]

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