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104 Possible Causes for Ecchymosis, Hypercellular Bone Marrow

  • Chronic Myeloid Leukemia

    In accelerated phase and blast crisis, the patient presents like acute leukemia with fever, bleeding, petechiae, ecchymosis and pallor due to overexpansion of bone marrow[] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[] It may also present with mild fever and night sweats due to an elevated basal level of metabolism. [4] Some ( petechiae and ecchymosis . [4] In these patients fevers are most[]

  • Myeloproliferative Disease

    […] infarction and perisplenitis Clinical symptoms can include the following: Pallor (except in patients with polycythemia vera) Plethora secondary to polycythemia Petechiae and/or ecchymosis[] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[] […] patients with myeloproliferative disease may include the following: Pallor, except in patients with polycythemia vera Plethora secondary to polycythemia Petechiae and/or ecchymosis[]

  • Polycythemia Vera

    Weakness, fatigue, headache, blood clotting, vertigo, tinnitus, irritability, dyspnea, visual disturbances, flushing of face, redness, or ruddy cyanosis, pruritus, ecchymosis[] bone marrow 5.[] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[]

  • Acute Leukemia

    Signs of bleeding may include presence of petechiae, ecchymosis and swollen gums.[] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[]

  • Paroxysmal Nocturnal Hemoglobinuria

    Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[] The degree of marrow failure may vary from severe aplastic anemia to a decrease in the number of hematopoietic stem cells.[]

  • Essential Thrombocythemia

    A 69-year-old woman with essential thrombocythemia (ET) developed giant ecchymosis, and she was admitted to hospital.[] ET is usually characterized by a hypercellular bone marrow, including increased numbers of megakaryocytes.[] Platelets aggregation studies • impaired platelet aggregation • Spontaneous platelets aggregation Bone marrow biopsy • Hypercellular marrow (90%) • Megakaryocytic hyperplasia[]

  • Passovoy Factor Defect

    [from OMIM ] Bruising susceptibility MedGen UID: 140849 • Concept ID: C0423798 • Finding An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood[] The combination of pancytopenia and hypercellular bone marrow suggested that this patient had myelodysplastic syndrome (MDS).[] The probands older son, aged 7, by her first marriage,had axillary ecchymosis as an infant from the age of3 weeks as a result of being picked up. He bruiseseasily.[]

  • Hairy Cell Leukemia

    In addition, patients may present with cutaneous manifestations, such as herpes zoster, cellulitis, abscess, pyoderma, dermatophytosis, leukemia cutis, ecchymosis, and purpura[] Fig. 2: TRAP ; Fig. 3: hypercellular bone marrow with monotonous "fried egg" lymphocytes with abundant cytoplasm Cytology description Small / intermediate size cells with[] Bone marrow aspiration showed hypercellular marrow with cells characterized by irregular windblown-appearing cell borders with pseudopod-like projections.[]

  • Acute Undifferentiated Leukemia

    Bleeding may be from the skin, gastrointestinal tract and reproductive system, evidenced by epistaxis, petechiae, ecchymosis, hematuria, and abnormal uterine bleeding.[] 7 Year Member Joined: Feb 16, 2008 Messages: 47 Likes Received: 0 This was from a practice teaching case and I'm not sure I agree...Hypercellular bone marrow with 94% blasts[]

  • Amegakaryocytic Thrombocytopenia

    There was ecchymosis over the abdomen and thigh, largest measuring 3 cms over the abdomen. (Figure 1 & 2) Vitals - Pulse was 90 /min, good volume.[] […] by normal-to-hypercellular bone marrow.[] […] megakaryocytes in an otherwise normal bone marrow. [1] It needs to be differentiated from the more common disorder, immune thrombocytopenic purpura (ITP), which is characterized[]

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