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46 Possible Causes for Elevated Sedimentation Rate, Localized Edema, Patient Appears Chronically Ill

  • Multiple Myeloma

    The typical presentation of multiple myeloma is anemia, back pain, and an elevated sedimentation rate.[ncbi.nlm.nih.gov] The presence of unexplained anemia, kidney dysfunction, a high erythrocyte sedimentation rate, lytic bone lesions, elevated beta-2 microglobulin, or a high serum protein ([en.wikipedia.org]

  • Necrotizing Fasciitis

    Via infection, local inflammatory processes produce increased amounts of purulence, local edema, and eventually necrosis in the deep tissues, leading to pain out of proportion[clinicaladvisor.com] The process begins as local cellulitis, with erythema, edema, pain, and marked tenderness.[infectiousdiseaseadvisor.com] Symptoms and signs may include localized pain, edema, erythema or violaceous coloration, crepitus, soft tissue necrosis, blistering, and findings consistent with systemic[webeye.ophth.uiowa.edu]

  • Cellulitis

    Physical Assessment  Local symptoms:  Erythema and edema of area  Warm to touch,  Possibly fluctuant (tense, firm to palpation)  May resemble peau d’orange  Advancing[slideshare.net] […] erythrocyte sedimentation rate, elevated C-reactive protein Skin surface swab, blood cultures, cutaneous aspirates are NOT routinely recommended Recommended ONLY if malignancy[cancertherapyadvisor.com] illness for those who experience recurrent episodes, though many patients appear unaware of this.[bjgp.org]

  • Rheumatoid Arthritis

    […] an autoreactive antibody to the Fc receptors is mediated through the antibody's N-glycans, which are altered to promote inflammation in people with RA.This contributes to local[en.wikipedia.org] In a patient with inflammatory arthritis, the presence of a rheumatoid factor or anti-citrullinated protein antibody, or elevated C-reactive protein level or erythrocyte sedimentation[ncbi.nlm.nih.gov] Patients with rheumatoid arthritis appear undernourished and chronically ill. Most are anemic because of the effect of the disease on blood-forming organs.[medical-dictionary.thefreedictionary.com]

  • Pancreatic Abscess

    The net result is localized tissue destruction and inflammation. Often there are edema, hemorrhage, necrosis, thrombosis and hyperplasia of lymphoid follicles.[atsu.edu] Blood tests showed poorly controlled diabetes with a random blood sugar level of 23.8 mmol/L (reference range: 3.5 to 6.0 mmol/L) and an elevated erythrocyte sedimentation[pancreas.imedpub.com] In these settings not only is an appropriate anaerobic environment obtained but other local host defenses are also impaired, thereby enabling these opportunists to initiate[atsu.edu]

  • Abdominal Visceral Abscess

    […] pain in the abdomen Pain is not severe Pain is relieved by pressure Edema of the feet Urinary difficulty Slight edema (primarily of the lower limbs) Symptoms generally occur[americandragon.com] General signs of inflammation (such as elevated sedimentation rate, leucocytosis, and fever) may be absent.[jmedicalcasereports.biomedcentral.com] In contrast, if a patient develops abdominal pain, becomes febrile, or appears critically ill, surgical exploration should be considered for repair or drainage, especially[wjes.biomedcentral.com]

  • Tubo-Ovarian Abscess

    […] and spreading edema.[glowm.com] […] erythrocyte sedimentation rate Elevated C-reactive protein Laboratory evidence of cervical infection with Neisseria gonorrhea or Chlamydia trachomatis (ie, culture or DNA[accessemergencymedicine.mhmedical.com] […] high microcirculation perfusion and the edema of cells, thus presenting high signal intensity on DWI.[journals.plos.org]

  • Bronchial Adenocarcinoma

    Symptoms of Pancoast syndrome Severe, localized pain in the axilla and shoulder Horner syndrome Atrophy of arm and hand muscles Edema of the arm, facial swelling, morning[amboss.com]

  • Inflammatory Bowel Disease Type 1

    Fibrofatty proliferation is hyperintense on T2-weighted images and is related to regional mesenteritis or edema and dilatation of local vessels.[emedicine.com] […] erythrocyte sedimentation rate or level of C-reactive protein.[msdmanuals.com] A: Colonoscopy revealed localized yellowish slough, rectal edema, erythema, and superficial ulcerations; B: Histology (hematoxylin and eosin) shows smooth muscle hyperplasia[ncbi.nlm.nih.gov]

  • Subphrenic Abscess

    The net result is localized tissue destruction and inflammation. Often there are edema, hemorrhage, necrosis, thrombosis and hyperplasia of lymphoid follicles.[atsu.edu] The erythrocyte sedimentation rate (ESR) is commonly elevated. Liver function tests are helpful.[es.slideshare.net] Subsequent edema formation and extravasation of proteins are often severe and may cause shock.[symptoma.com]