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48 Possible Causes for Elevated Sedimentation Rate, Normocytic Normochromic Anemia, Renal Amyloidosis

  • Rheumatoid Arthritis

    A normochromic (or slightly hypochromic)-normocytic anemia occurs in 80%; Hb is usually 10 g/dL.[] In a patient with inflammatory arthritis, the presence of a rheumatoid factor or anti-citrullinated protein antibody, or elevated C-reactive protein level or erythrocyte sedimentation[] Renal amyloidosis can occur as a consequence of untreated chronic inflammation.[]

  • Multiple Myeloma

    […] typically normochromic/normocytic renal failure proteinuria hypercalcemia Presentation may also be with a complication, including: pathological fracture vertebral compression[] The typical presentation of multiple myeloma is anemia, back pain, and an elevated sedimentation rate.[] The technic of needle biopsy of the kidney has helped to clarify the place of amyloidosis in the spectrum of renal disease and is of particular importance in the differential[]

  • Hodgkin's Disease

    Complication Renal amyloidosis followed by contracted kidney and uremia Intoxication Septic complication Cardiovascular disease Second malignancy, such as leukemia, non-Hodgkin's[]

  • Chronic Kidney Insufficiency

    Hyperphosphatemia and hyperparathyroidism are common findings, whereas a complete blood count (CBC) reveals anemia with normochromic and normocytic characteristics, thus excluding[] Congenital obstructive urinary flow disorders, chronic-recurrent nephrolithiasis or amyloidosis can permanently damage the kidneys and lead to chronic renal failure.[] The anemia of CKD is normochromic-normocytic, with an Hct of 20 to 30% (35 to 40% in patients with polycystic kidney disease ).[]

  • Waldenstrom Macroglobulinemia

    Laboratory tests A complete blood count in WM exhibits leukopenia, normocytic normochromic anemia, and thrombocytopenia.[] […] erythrocyte sedimentation rate.[] […] manifestations have been described: glomerulonephritis, due to IgM or cryoglobulins depositions and nephrotic syndrome, commonly secondary to amyloidosis or to IgM thrombi[]

  • Ankylosing Spondylitis

    Anemia Patients may have a mild normochromic normocytic anemia, another nonspecific finding.[] Erythrocyte sedimentation rate and alkaline and creatinine phosphatase were elevated. There was no rheumatoid factor present.[] renal amyloidosis.[]

  • Pediatric Chronic Granulomatous Disease

    The erythrocyte sedimentation rate might be elevated in some patients. Hypergammaglobulinemia is commonly seen in patients with chronic granulomatous disease.[] End-stage renal disease occurs in this patient population and is attributed to various factors, including infections, amyloidosis, and nephrotoxic anti-infective agents.[] Elevated erythrocyte sedimentation rate. .. .. e. All of the above References 1. Boxer LA, Blackwood RA.[]

  • Acute Glomerulonephritis

    We report severe normocytic, normochromic anemia (hematocrit, 19.8%) in PSAGN in a 6-year-old girl with edema, macrohematuria, and proteinuria for 1 month.[] You can expect to see an elevated erythrocyte sedimentation rate and a depressed serum complement level.[] Secondary AA amyloidosis is the most devastating complication of FMF.[]

  • Polymyalgia Rheumatica

    . • The complete blood cell test reveals mild normocytic, normochromic anemia in 50% of cases. The white blood cell count may be normal or mildly elevated.[] Elevated erythrocyte sedimentation rate accompanies the symptoms. See also erythrocyte sedimentation rate.[] Renal involvement in PMR is extremely rare and very few cases of AA amyloidosis secondary to PMR have been described in literature.[]

  • Juvenile Rheumatoid Arthritis

    Complete blood cell count Leukocytosis with predominant granulocytes, normocytic, normochromic anemia of chronic disease and reactive thrombocytosis are typical.[] The only laboratory abnormalities in this patient included elevated serum transaminases, a mildly elevated erythrocyte sedimentation rate, and a moderately elevated level[] We report a case of a rare disorder of renal amyloidosis occurring as a complication of juvenile rheumatoid arthritis in a 16-year-old adolescent male.[]

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