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27 Possible Causes for Elevated Sedimentation Rate, Polyclonal Hyperglobulinemia

  • Chronic Active Hepatitis

    hyperglobulinemia.[hepatitiscentral.com] […] erythrocyte sedimentation rate Eosinophilia (uncommon) Biopsy Urgent liver biopsy, transjugular if appropriate, may help to confirm the clinical suspicion of acute autoimmune[emedicine.medscape.com] Additionally, some authorities require the presence of immunologic features, particularly high titers (usually more than 1:40) of certain non organic specific autoantibodies and polyclonal[hepatitiscentral.com]

  • Chronic Active Hepatitis B

    Aspartate aminotransferase and alanine aminotransferase levels were elevated (47 and 85 U/mL, respectively), but the erythrocyte sedimentation rate, and blood urea nitrogen[synapse.koreamed.org] hyperglobulinemia.[hepatitiscentral.com] Additionally, some authorities require the presence of immunologic features, particularly high titers (usually more than 1:40) of certain non organic specific autoantibodies and polyclonal[hepatitiscentral.com]

  • Idiopathic Cryoglobulinemia

    […] of white blood cells or platelets (due to cryoprecipitation on an automated counter) Complements: low C4 and CH50 levels, variable C3 levels Elevated erythrocyte sedimentation[clinicaladvisor.com] NOS ( R77.1 ) monoclonal gammopathy (of undetermined significance) ( D47.2 ) Excludes2 transplant failure and rejection ( T86 .-) D89.0 Polyclonal hypergammaglobulinemia[icd10coded.com] rate and C- reactive protein HCV RNA (positive in 80% of time, anti-HCV antibody may be negative) Positive ANA and other autoantibodies 3) Biopsy of affected tissue (skin[clinicaladvisor.com]

  • Rosai-Dorfman Disease

    rate.[ncbi.nlm.nih.gov] hyperglobulinemia.[ncbi.nlm.nih.gov] Additional findings may include fever, malaise, epistaxis, night sweats, weight loss, leukocytosis, elevated erythrocyte sedimentation rate and hypergammaglobulinemia.[orpha.net]

  • Pediatric Chronic Granulomatous Disease

    The erythrocyte sedimentation rate might be elevated in some patients. Hypergammaglobulinemia is commonly seen in patients with chronic granulomatous disease.[lecturio.com] Polyclonal hyperglobulinemia 3. Elevated acute phase reactants such as ESR or CRP 4. Normal studies of T and B lymphocyte immunity Diagnostic test 1.[clinicalmolecularallergy.biomedcentral.com] Elevated erythrocyte sedimentation rate. .. .. e. All of the above References 1. Boxer LA, Blackwood RA.[hawaii.edu]

  • Castleman Disease

    Laboratory studies showed anemia and mildly elevated sedimentation rate.[ncbi.nlm.nih.gov] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov] He was found to have an anterior mediastinal mass with anemia and an elevated sedimentation rate.[cancertherapyadvisor.com]

  • Thyroiditis

    sedimentation rate (ESR), suppression of iodine uptake Later hypothyroidism and antithyroid antibodies After weeks to months, patients become euthyroid Radiology images Images[pathologyoutlines.com] Plasma protein electrophoresis showed polyclonal hyperglobulinemia, with normal immunofixation.[edm.bioscientifica.com] The combination of a hard, painful thyroid with fever, elevated sedimentation rate and thyroid hormone levels are almost 100% diagnostic for the disease.[thyrosite.com]

  • IgG4-Related Retroperitoneal Fibrosis

    Laboratory data showed elevated erythrocyte sedimentation rate and hepatobiliary enzymes, renal dysfunction, high titers of antinuclear antibody, anti-SS-A antibody and anti-mitochondrial[ncbi.nlm.nih.gov] hyperglobulinemia.[hematologyandoncology.net] Blood tests demonstrated acute kidney injury (AKI) on CKD with elevated serum creatinine of 2.1 mg/dl, elevated C-reactive protein (CRP), and erythrocyte sedimentation rate[doi.org]

  • H Syndrome

    Laboratory tests show extremely elevated erythrocyte sedimentation rate, mild microcytic anemia, and elevated liver enzymes.[orpha.net] SHML causes lymph node enlargement in children frequently accompanied by fever, leukocytosis, elevated erythrocyte sedimentation rate, and polyclonal hypergammaglobulinemia[uniprot.org] RDD can be differentiated from Faisalabad histiocytosis by the presence of massive painless cervical lymphadenopathy , fever , elevated erythrocyte sedimentation rate and[wikidoc.org]

  • Multicentric Castleman's Disease

    hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org] […] erythrocyte sedimentation rate, IL-6, vascular endothelial growth factor (VEGF), and fibrinogen; positive anti-nuclear antibody, anti-erythrocyte autoantibodies, and anti-platelet[checkorphan.org] Patients with MCD may reveal raised serum C-reactive protein level, polyclonal hyperglobulinemia, anemia of microcytic hypochromic nature, low albumin level, and high cholesterol[lungindia.com]

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