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838 Possible Causes for EMG Shows Evidence of Reinnervation, Muscle Biopsy Abnormal, Weakness after Climbing Stairs

  • Duchenne Muscular Dystrophy

    Diagnosis of Duchenne Muscular Dystrophy A muscle biopsy (taking a sample of muscle) for dystrophin studies can be done to look for abnormal levels of dystrophin in the muscle[disabled-world.com] […] symptoms are noticed, such as weakness, clumsiness, a Gowers’ sign, difficulty with stair climbing, or toe walking.[ncbi.nlm.nih.gov] […] fibers) For Duchenne and Becker muscular dystrophies, muscle biopsy may show whether dystrophin, a muscle protein, is missing or abnormal, and DNA testing is used to analyze[webmd.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Muscular Dystrophy

    This condition is typically characterized by large and abnormally distributed mitochondria on muscle biopsy, which can distinguish this condition from the other muscle conditions[ncbi.nlm.nih.gov] Under the microscope, the muscle of a positive biopsy generally shows dead tissue and abnormally large muscle fibers.[cedars-sinai.edu] Muscle biopsies from subjects 1 and 3 were severely dystrophic with abnormal immunofluorescence and western blotting indicative of α-dystroglycan hypoglycosylation.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Becker Muscular Dystrophy

    Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin.[ncbi.nlm.nih.gov] As time goes by, there may be muscle weakness which causes difficulty with running, climbing stairs or walking long distances.[treat-nmd.eu] Elevated serum CK Skeletal muscle biopsy showing decreased dystrophin quantity Panel overlap The gene on this panel is also included on our Autism Intellectual Disability[unmc.edu]

    Missing: EMG Shows Evidence of Reinnervation
  • Polymyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] & have to be careful on stairs & ladders (don't tell the Professors who are looking after me that I climb ladders) They know.I am very positive & determined not to let it[steadyhealth.com] Laboratory testing showed elevated muscle enzymes and myopathic abnormalities on electromyographic examination.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy abnormalities in two individuals very early in the course of their disease suggest that biopsy would probably be useful in detection of preclinical disease in[pediatrics.aappublications.org] She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov] Some LGMD subtypes have distinguishing features, including pattern of muscle involvement, cardiac abnormalities, extramuscular involvement, and muscle biopsy findings.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Polymyalgia Rheumatica

    Microscopic and laboratory examination of muscle tissue samples (biopsy) from affected individuals does not usually reveal any muscle abnormality.[rarediseases.org] Muscle biopsy is recommended in patients with inflammatory myositis. How is PMR treated? Glucocorticoids are the mainstay of therapy for patients diagnosed with PMR.[news-medical.net] […] diagnosis of polymyalgia rheumatica may be confirmed by a thorough clinical examination including a detailed patient history and specialized blood testing that demonstrates an abnormally[rarediseases.org]

    Missing: EMG Shows Evidence of Reinnervation
  • Motor Neuron Disease

    For patients with MND affecting the LMNs, the EMG will show evidence of: (1) acute denervation, which is ongoing as motor neurons degenerate, and (2) chronic denervation and[en.wikipedia.org] The results of electromyography and muscle biopsy were compatible with ALS. However, supranuclear vertical gaze palsy and slow saccades are seen.[ncbi.nlm.nih.gov] reinnervation of the muscle, as the remaining motor neurons attempt to fill in for lost motor neurons.[en.wikipedia.org]

    Missing: Weakness after Climbing Stairs
  • Amyotrophic Lateral Sclerosis

    Only about 10% of ALS patients have abnormal nerve conduction study results, but the test can also suggest other diagnoses. A muscle biopsy.[webmd.com] Patients typically have difficulty rising from a chair, climbing stairs, and walking. Increased temperatures from fever or the environment may worsen the weakness.[web.archive.org] Patients may experience transient worsening after hot baths and showers or during systemic illnesses.[web.archive.org]

    Missing: EMG Shows Evidence of Reinnervation
  • Dermatomyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] Running, climbing stairs, sitting from a lying position or standing from a seated position may become difficult.[arthritis.org] Muscle biopsy abnormalities at some time during their disease: Muscle fiber destruction; Muscle fiber regeneration; Perivascular and interstitial inflammatory infiltrates[clinicaltrials.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Glycogen Storage Disease Type 5

    DNA testing In northern Europe 85% patients show an abnormal gene encoding for muscle phosphorylase. DNA testing is supposed to be less invasive then muscle biopsy.[symptoma.com] No sport activities were possible and the boy had even difficulties climbing stairs due to muscle weakness.[ojrd.biomedcentral.com] Diagnosis depends on findings from patient history and physical examination, creatine kinase testing, muscle biopsy, electromyelography, and ischemic forearm testing.[emedicine.com]

    Missing: EMG Shows Evidence of Reinnervation