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12 Possible Causes for Emotional Lability, Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs

Did you mean: Emotional Lability, Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[] Case 1: 24-year-old male, known alcoholic, was admitted with left hemiplegia and features of bulbar and pseudobulbar palsy with dysphagia, dysarthria and emotional lability[] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[]

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[] These include emotional lability, depression and personality changes. Later onset of pyramidal and extrapyramidal signs.[] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[]

  • Binswanger Disease

    Moreover, deficits in attention, behavioral changes and emotional lability are clinical hallmarks of BD and other forms of dementia.[] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] Features of pseudobulbar palsy Emotional problems - eg, emotional lability, psychomotor retardation or depression.[]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[] lability.[] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[] Clinical features of sCJD include myoclonic jerks, memory deficits, cerebellar signs (ataxia, nystagmus, tremors), pyramidal/corticospinal tract dysfunctions (spasticity,[]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1, 2 ].[] ., emotional lability, depression, anxiety, impulsivity, compulsions, hallucinations, perseveration, inattention, and hyperactivity), and cognitive decline.[] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[] lability Emotional instability 0000712 Hyperreflexia Increased reflexes 0001347 Hypomimic face Dull facial expression 0000338 Laryngeal dystonia 0012049 Micrographia 0031908[] pallidus, on T2-weighted images.[]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[] Patients in the choreic group (11%) - Predominantly characterized by choreoathetoid abnormal movements associated with dystonia Psychiatric features include emotional lability[] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[]

  • Alopecia - Hypogonadism - Extrapyramidal Syndrome

    tract signs, and marked cognitive decline and neuropsychiatric symptoms.[] lability Prominent supraorbital ridges Decreased muscle mass Malar prominence High palate Short ear Nevus Broad chin Oval face Progressive spastic paraplegia Prominent forehead[] The eye-of-the-tiger sign, T2-weighted hypointense signal in the globus pallidus with a central region of hyperintensity, is virtually pathognomonic for PKAN.[]

  • Basal Ganglia Mass Lesion

    Neurologic examination demonstrated a right hemiparesis with hypereflexia, bilateral pyramidal tract signs, right facial nerve palsy, dysarthria, dystonia that was more prominent[] Emotional lability, personality change and cognitive problems usually occur a little later.[] lability; caused by diseases such as multiple sclerosis, motor neuron disease, and stroke that affect the motor fibers traveling from the cerebral cortex to the lower brainstem[]

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