Create issue ticket

74 Possible Causes for End-Plate Irregularities

  • Wolcott-Rallison Syndrome

    Wolcott-Rallison syndrome is a rare disease presenting with insulin-dependent diabetes mellitus (DM) before 6 months old, skeletal dysplasia after 6 months old, and liver failure. Other manifestations are renal failure, microcephaly, epilepsy, central hypothyroidism, neutropenia, and dental and dermal problems. The cases[…][ncbi.nlm.nih.gov]

  • Primrose Syndrome

    Primrose syndrome is a rare, slowly progressive genetic disorder that can vary symptomatically between individual cases, but is generally characterised by ossification of the external ears, learning difficulties, and facial abnormalities. It was first described in 1982 in Scotland's Royal National Larbert Institution by Dr[…][en.wikipedia.org]

  • Schmid Metaphyseal Chondrodysplasia

    It is characterized by spinal involvement comprising mild platyspondyly, vertebral body abnormalities, and end-plate irregularity.[genecards.org] Short limbed rhizomelic dwarfism of late onset (2 - 4 yrs of age) Mild to moderate spinal deformity, normal craniofacial structure slight irregularities of vertebral end plates[orthopaedicsone.com] Radiography usually shows sclerosis of the ribs, flaring of the metaphyses, and a wide irregular growth plate, especially of the knees.[genecards.org]

  • Roifman Syndrome

    Nat Commun. 2015 Nov 2;6:8718. doi: 10.1038/ncomms9718. Merico D 1 , Roifman M 2, 3, 4 , Braunschweig U 5 , Yuen RK 1 , Alexandrova R 1 , Bates A 6 , Reid B 6 , Nalpathamkalam T 1 , Wang Z 1 , Thiruvahindrapuram B 1 , Gray P 7 , Kakakios A 8 , Peake J 9, 10 , Hogarth S 9, 10 , Manson D 11 , Buncic R 12 , Pereira SL 1 ,[…][ncbi.nlm.nih.gov]

  • Rhizomelic Chondrodysplasia Punctata Type 2

    The case of a Yemeni girl with isolated peroxisomal acyl-CoA:dihydroxyacetonephosphate acyltransferase (DHAPAT) deficiency is reported. She had rhizomelic chondrodysplasia punctata, microcephaly, failure to thrive, delayed motor and mental development, and spastic quadriplegia. Deficient de novo plasmalogen synthesis[…][ncbi.nlm.nih.gov]

  • Scheuermann's Disease

    plate irregularity and disc space narrowing.[neuroradiologycases.com] plate irregularities. 20 - 45 o of kyphosis is normal in the 15 - 20 year old.[orthopaedicsone.com] Incidences of associated SD and four radiographic signs of SD that were Schmorl's node, irregular vertebral end plate, posterior bony avulsion of the vertebra and wedge-shaped[ncbi.nlm.nih.gov]

  • Spondyloepimetaphyseal Dysplasia Type PAPSS2

    Radiology Radiographic features include delayed epiphyseal ossification at the hips and knees, platyspondyly with irregular end plates and narrowed joint spaces, diffuse early[ipfs.io] Diagnosis [ edit ] Radiology [ edit ] Radiographic features include delayed epiphyseal ossification at the hips and knees, platyspondyly with irregular end plates and narrowed[en.wikipedia.org] Diagnosis Radiology Radiographic features include delayed epiphyseal ossification at the hips and knees, platyspondyly with irregular end plates and narrowed joint spaces,[wikiwand.com]

  • Kyphosis

    […] angle is seen in the following condition: straight back syndrome traditionally measured using the Cobb angle may over-estimate kyphosis if there is concomitant vertebral end-plate[radiopaedia.org] end-plates noted on radiographs, less vertebral body wedging Presentation Symptoms may complain of thoracic or lumbar pain cosmetic concerns Physical exam increased kyphosis[orthobullets.com] irregularities 1 the alternative Cobb 1 or vertebral centroid angles 3 have been proposed to negate the aforementioned over-estimation History and etymology Derived from[radiopaedia.org]

  • Spondyloepiphyseal Dysplasia Type Reardon

    Symptoms via clinical synopsis from OMIM: 58 Growth Height: short stature Skeletal Spine: lumbar lordosis irregular vertebral end plates atlanto-axial subluxation os odontoideum[malacards.org]

  • Brachyolmia, Recessive Hobaek Type

    […] of the vertebral end plates.[ncbi.nlm.nih.gov] Radiographic features include platyspondyly with rectangular vertebral bodies and irregular end plates, broad ilia, metaphyseal changes of the proximal femur, including short[ncbi.nlm.nih.gov] […] radiographic manifestations are primarily limited to the spine, and consist of universal platyspondyly with lateral extension of the vertebral bodies beyond the pedicles and irregularity[ncbi.nlm.nih.gov]

Further symptoms