Create issue ticket

185 Possible Causes for End-Plate Irregularities, Excessive Trabeculation in Right Ventricle, Reduced Pancreatic Beta Cells

  • Wolcott-Rallison Syndrome

    [Crossref], [Web of Science ], [Google Scholar] ) showed that acute ablation of PERK results in reduced cell proliferation with abnormal insulin trafficking and secretion.[doi.org] Studies in EIF2AK3/PERK knockout mouse demonstrated that PERK is required for pancreatic beta cell development during fetal and early neonatal development ( 7 Zhang P, McGrath[doi.org]

    Missing: Excessive Trabeculation in Right Ventricle
  • Roifman Syndrome

    […] within the ventricular wall, usually involving the left ventricle, although the right ventricle and interventricular septum can also be affected.[ncbi.nlm.nih.gov] […] and prominent trabeculations and deep intratrabecular recesses within the ventricular wall, usually involving the left ventricle, although the right ventricle and interventricular[unboundmedicine.com] Noncompaction of the ventricular myocardium, sometimes referred to as "spongy myocardium", appears as excessive and prominent trabeculations and deep intratrabecular recesses[ncbi.nlm.nih.gov]

    Missing: Reduced Pancreatic Beta Cells
  • Primrose Syndrome

    Abstract Primrose syndrome is a unique condition of intellectual disability, dysmorphic facial features, and specific minor abnormalities including large calcified ear auricles. Only six patients have been previously reported. We describe a Brazilian boy with the striking similar facies and the main clinical findings that[…][doi.org]

    Missing: Excessive Trabeculation in Right Ventricle Reduced Pancreatic Beta Cells
  • Schmid Metaphyseal Chondrodysplasia

    It is characterized by spinal involvement comprising mild platyspondyly, vertebral body abnormalities, and end-plate irregularity.[genecards.org] Short limbed rhizomelic dwarfism of late onset (2 - 4 yrs of age) Mild to moderate spinal deformity, normal craniofacial structure slight irregularities of vertebral end plates[orthopaedicsone.com] Radiography usually shows sclerosis of the ribs, flaring of the metaphyses, and a wide irregular growth plate, especially of the knees.[genecards.org]

    Missing: Excessive Trabeculation in Right Ventricle Reduced Pancreatic Beta Cells
  • Rhizomelic Chondrodysplasia Punctata Type 2

    The case of a Yemeni girl with isolated peroxisomal acyl-CoA:dihydroxyacetonephosphate acyltransferase (DHAPAT) deficiency is reported. She had rhizomelic chondrodysplasia punctata, microcephaly, failure to thrive, delayed motor and mental development, and spastic quadriplegia. Deficient de novo plasmalogen synthesis[…][ncbi.nlm.nih.gov]

    Missing: Excessive Trabeculation in Right Ventricle Reduced Pancreatic Beta Cells
  • Hypoglycemia

    If the tumor is malignant or cannot be operated on, certain medications may be able to suppress insulin release from the diseased pancreatic beta cells.[emedicinehealth.com] Special tests by the endocrinologist may assist the surgeon in removing less pancreatic tissue, reducing the risk of diabetes after surgery.[emedicinehealth.com]

    Missing: End-Plate Irregularities Excessive Trabeculation in Right Ventricle
  • Insulin Resistance

    Reducing pancreatic beta-cell activity b. Increasing the amount of glucose circulating in the blood c. Raising blood pressure d.[todaysdietitian.com] Fructose will generally produce smaller insulin excursions upon consumption because it does not stimulate the secretion of insulin from pancreatic beta cells, whereas glucose[doi.org] It is believed that the ability of the pancreatic beta cells to meet the demand posed by progressive insulin resistance ultimately reaches its limits.[doi.org]

    Missing: End-Plate Irregularities Excessive Trabeculation in Right Ventricle
  • Scheuermann's Disease

    plate irregularity and disc space narrowing.[neuroradiologycases.com] Vertebral end-plate flattening and irregularity is seen without vertebral fracture or scoliosis.[healio.com] plate irregularities. 20 - 45 o of kyphosis is normal in the 15 - 20 year old.[orthopaedicsone.com]

    Missing: Excessive Trabeculation in Right Ventricle Reduced Pancreatic Beta Cells
  • Diabetic Enteropathy

    […] autoimmune activity that destroys pancreatic beta cells.[vector.childrenshospital.org] Thus far, their mouse data indicate that the genetically engineered cells home to the pancreas, reduce abnormal immune-cell activity and reverse hyperglycemia, and that cells[hms.harvard.edu] Thus far, their mouse data indicate that the genetically engineered cells home to the pancreas, reduce abnormal immune-cell activity and reverse hyperglycemia (see abstract[vector.childrenshospital.org]

    Missing: End-Plate Irregularities Excessive Trabeculation in Right Ventricle
  • Diabetes Mellitus

    Reduced insulin exocytosis in human pancreatic beta-cells with gene variants linked to type 2 diabetes.[ncbi.nlm.nih.gov] They lower plasma glucose by stimulating pancreatic beta-cell insulin secretion and may secondarily improve peripheral and hepatic insulin sensitivity by reducing glucose[msdmanuals.com] The biguanides, unlike the SUs, do not stimulate insulin secretion by the pancreatic beta cells.[revespcardiol.org]

    Missing: End-Plate Irregularities Excessive Trabeculation in Right Ventricle