Enlarged Sella: Causes & Reasons

Possible Causes for Enlarged Sella

Either a normal sized (empty sella) or enlarge sella (empty enlarged sella) presents partly or totally filled with cerebrospinal fluid. [thamburaj.com]

The empty sella syndrome (ESS) is well documented in adults, and although the same phenomenon of herniation of the arachnoid space into the enlarged sella turcica has been [ncbi.nlm.nih.gov]

[…] syndrome Etymology: AS, oemettig, unoccupied; L, sella, saddle an abnormal enlargement of the sella turcica filled with cerebrospinal fluid. [medical-dictionary.thefreedictionary.com]

Giant-Cell Granulomatous Hypophysitis

enlarged sella, and extension of enhancement to the optic chiasm (10, 20, 26). [ajnr.org]

Magnetic resonance imaging (MRI) scan demonstrated an enlarged sella and a large well-marginated patchily enhancing soft tissue mass within sellar and suprasellar regions. [cancerjournal.net]

Plain x-ray skull films have usually been normal, but polytomography of the sella may demonstrate an enlarged, rounded sella without evidence of focal erosion. [pituitaryadenomas.com]

Chromophobe Adenoma

Abstract A 50-year-old man with bitemporal hemianopsia and an enlarged sella turcica was found to have hyperthyroidism with elevated serum thyrotropin levels (17 mμg per milliliter [nejm.org]

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

Since then, others 3, 4 have reported similar cases, some of which showed enlargement of the sella turcica before adrenalectomy. [nejm.org]

Somatotrophic Pituitary Adenoma

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

If it is in the sella, determine whether or not the sella is enlarged. [radiologyassistant.nl]

[…] beyond the sella turcica. [drugs.com]

Pituitary Cyst

MRI scans are useful in evaluating ESS and differentiating it from other disorders that produce an enlarged sella. [pituitary.org.uk]

CT typically shows an enlarged sella turcica containing a cystic mass, which can be either hypodense or isodense with brain. [pituitaryadenomas.com]

Over time, cerebrospinal fluid (CSF) pulsations may enlarge the sella and compress the gland against the floor of the sella. [emedicine.medscape.com]

Launois Syndrome

sella turcica. [symptoma.com]

sella turcica on skull radiograph, CT scan demonstrates pituitary tumor). [accessanesthesiology.mhmedical.com]

[…] turcica Pituitary dwarfism with small sella turcica Pituitary gland enlarged Pituitary hemorrhage Pituitary infarction Posterior pituitary disorder Primary hypothalamic insufficiency [icd9data.com]

Corticotroph Pituitary Adenoma

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

Over time, cerebrospinal fluid (CSF) pulsations may enlarge the sella and compress the gland against the floor of the sella. [emedicine.medscape.com]

Since then, others 3, 4 have reported similar cases, some of which showed enlargement of the sella turcica before adrenalectomy. [nejm.org]

Pituitary Neoplasm

A pituitary tumor tends to produce an enlarged sella (sella turcica). Alternatively, an enlarged sella may represent empty sella syndrome. [merckmanuals.com]

Stage III: macroadenomas with enlargement and invasion of the floor or suprasellar extension. Stage IV is destruction of the sella. [en.wikipedia.org]

Most headaches probably arise from stretching of the diaphragma sellae by the enlarging mass; obstruction of the aqueduct of Sylvius or the foramina of Monro is a rare complication [academic.oup.com]

Basophil Adenoma

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

Stage III: macroadenomas with enlargement and invasion of the floor or suprasellar extension. Stage IV is destruction of the sella. [en.wikipedia.org]

Prolactin-producing adenomas: usually intrasellar; are often small (less than 10 mm) but may become large enough to enlarge the sella turcica. [patient.info]

Pituitary Adenoma

[…] floor Grade II: Enlarged sella with an intact floor Grade III: Localized erosion or destruction of the sellar floor Grade IV: Diffusely eroded or destroyed floor Treatment [en.wikibooks.org]

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

A and B, Coronal T1-weighted images of the sella turcica before ( A ) and after ( B ) intravenous contrast agent administration shows an enlarged pituitary gland with expansion [ajnr.org]

Gigantism

He had an enlarged sella turcica and features of acromegaly. He also had gynecomastia and hypergonadotropic hypogonadism. [amjmed.com]

However, a sellar radiograph revealed a considerably enlarged sella turcica (3 cm, 1.2 in). [ncbi.nlm.nih.gov]

CT, MRI, or skull x-rays disclose cortical thickening, enlargement of the frontal sinuses, and enlargement and erosion of the sella turcica. [merckmanuals.com]

Prolactinoma

X-ray of the skull showed an enlarged sella without any erosion. [functionalneurology.com]

A macroadenoma, defined as larger than 10 mm in diameter, can cause enlargement of the sella turcica. 1,4 The larger the size of the prolactinoma, the greater the prolactin [mdedge.com]

Enlargement of the gland can cause local symptoms such as headaches or visual disturbances. [pituitarydisorder.net]

Hypertrichotic Osteochondrodysplasia

sella; [Spine]; Platyspondyly; Ovoid-shaped vertebral bodies (childhood); Cuboid-shaped vertebral bodies (post-puberty); [Pelvis]; Hypoplastic ishchiopubic rami; Coxa valga [genome.jp]

0000212 Hypoplastic ischiopubic rami 0008822 Large for gestational age Birth weight > 90th percentile Birthweight > 90th percentile [ more ] 0001520 Large sella turcica Big [rarediseases.info.nih.gov]

[…] and scapulae]; Widened ribs; Narrow shoulders ABDOMEN: [External features]; Umbilical hernia SKELETAL: Osteoporosis; Delayed bone age; [Skull]; Widened posterior fossa; Enlarged [genome.jp]

Craniopharyngioma

Other signs include enlarged sella, bony erosion of the sella, dorsum, or clinoids, and signs of increased ICP. [thamburaj.com]

CR that have enlarged the sella and are predominantly outside of the arachnoid membrane can be excised transsphenoidally ( 33, 59 – 61 ). [doi.org]

Enlargement of the sella is of primary importance when using this approach, since it implies that the tumor took origin under the diaphragma sellae, thus it is not attached [thamburaj.com]

Sellar Tumor with Suprasellar Extension

[…] of the sella turcica. 378 MRI showed an intrasellar cystic tumor causing enlargement of the sella turcica. 379 MRI showed an intrasellar cystic tumor causing enlargement [pathology.jhu.edu]

[…] intact I: sella normal or focally expanded; tumor II: sella enlarged; tumor >= 10mm Sphenoid extension III: localized perforation of sellar floor IV: diffuse destruction [dss.dign.eu]

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

Suprasellar Tumor

Erosion of the sella is most unusual in basophile adenoma, although occasionally a case is encountered in which a basophile adenoma enlarges the sella to such an extent that [docplayer.net]

Initially confined to the sella turcica, but may enlarge and become invasive after bilateral adrenalectomy (Nelson's syndrome). [patient.info]

Juvenile Myxedema

This paper presents a case of enlargement of the sella turcica in a child of short stature. [mdedge.com]

X-ray skull sellar view [Figure 1] showed an enlarged sella with hypoplastic maxillary and frontal sinuses. [thetrp.net]

Figure 1: X ray skull sellar view showing enlarged sella hypoplastic maxillary and frontal sinuses Click here to view Figure 2: X ray wrist showing bone age of 10 years (chronological [thetrp.net]

Hypothalamic Lesion

A pituitary tumor tends to produce an enlarged sella (sella turcica). Alternatively, an enlarged sella may represent empty sella syndrome. [merckmanuals.com]

If it is in the sella, determine whether or not the sella is enlarged. [radiologyassistant.nl]

Does the lesion enlarge the sella? An enlarged sella is more compatible with an intrasellar lesion like pituitary adenoma or RCC. 3. [pubs.rsna.org]

Sclerosteosis

Radiographs reveal increased density of the bones of the skull with enlarged frontal sinuses, enlarged sella turcica and sclerosis of the cranial foramina. [fdna.health]

The mandible becomes massively enlarged and there is usually hypodontia. [fdna.health]

Skeletal Dysplasia

Skull X-rays revealed turribrachycephaly with extensive copper beaten appearance in the frontal region, enlarged sella, and flattening of forehead ( Fig. 2C ). [ncbi.nlm.nih.gov]

sella, flat forehead, midfacial hypoplasia, and prognathism. ( D ) Radiograph of the anteroposterior view of skull showing “copper beaten' appearance and multiple unerupted [ncbi.nlm.nih.gov]

[…] terminal phalanges of all toes. ( C ) Radiograph of the lateral view of skull showing turribrachycephaly with prominent “copper beaten” appearance of the frontal region, enlarged [ncbi.nlm.nih.gov]

Pituitary Disorder

A pituitary tumor tends to produce an enlarged sella (sella turcica). Alternatively, an enlarged sella may represent empty sella syndrome. [merckmanuals.com]

[…] or completely compressing the gland and may enlarge the sella turcica. [msdmanuals.com]

The sella turcica may enlarge, and the pituitary gland may shrink, causing the sella to appear empty on imaging studies. [msdmanuals.com]

Hajdu-Cheney Syndrome

sella dolichocephaly platybasia with or without basilar invagination Spine kyphoscoliosis spondylolisthesis biconcave vertebrae Maxillofacial hypoplastic maxilla malalignment [radiopaedia.org]

In one of the cases an enlarged sella turcica was associated with no abnormality of endocrine function. [typeset.io]

[…] osteolysis is also seen Skull bathrocephaly (bulging of squamous occipital bone) delayed closure of sutures thickening of the mastoids aplasia of the frontal sinuses J-shaped enlarged [radiopaedia.org]

Chiasmal Syndrome

The neuroradiological differential diagnosis of an enlarged sella turcica is given. [ncbi.nlm.nih.gov]

[…] and enlarged diaphragma sellae. [78stepshealth.us]

[…] common; in one study, defects >5 mm were found in 39% of normal autopsy cases.97 The sella is characteristically enlarged, but an empty sella may be of normal size. [medtextfree.wordpress.com]

Sheehan Syndrome

[…] turcica and the posterior deviation of the pituitary stalk (which suggested the empty sella syndrome) without enlargement of the sella turcica (confirmed by NMRI, which showed [ejinme.com]

The initial insult is caused by massive postpartum haemorrhage (PPH), leading to impaired blood supply to the pituitary gland, which has become enlarged during pregnancy. [ncbi.nlm.nih.gov]

CT ring enhancement surrounding a low attenuation empty sella 2 MRI early enlarged pituitary, with low T1, high T2 homogenous signal ring enhancement late empty sella of normal [radiopaedia.org]

Renon-Delille Syndrome

Mass of hypothalamus Mass of pituitary Oxytocin deficiency Pituitary abscess Pituitary apoplexy Pituitary cyst Pituitary disorder, posterior Pituitary dwarfism with large sella [icd9data.com]

Hypothalamo-Pituitary Disorder

A pituitary tumor tends to produce an enlarged sella (sella turcica). Alternatively, an enlarged sella may represent empty sella syndrome. [merckmanuals.com]

However, other visual-field defects may be present. 8) The sella turcica is enlarged in at least 90 % of patients with acromegaly. [intranet.tdmu.edu.ua]

During pregnancy, the pituitary gland enlarges due to hyperplasia and hypertrophy of the lactotroph cells, which produce prolactin. [emedicine.medscape.com]

Cutis Verticis Gyrata - Mental Deficiency

In patients with acromegaly and cutis verticis gyrata, enlarged sellae with enhancing intrasellar masses were present. [5, 66, 67] In MRI, severe abnormality of the occipital [emedicine.medscape.com]

[…] of the sella. [scielo.org.co]

[…] cases of men with mental retardation and CVG, two of them with a diagnosis of epilepsy, one with spastic dysplasia, one with congenital cataract; imaging reports showed enlargement [scielo.org.co]

Granulomatous Hypophysitis

Transphenoidal surgical exploration of the sella revealed a hypertrophic hypophysis, without adenomatous tissue. [revistaneurocirugia.com]

Plain x-ray films and C.T. were normal, but M.R.I. disclosed an enlarged sellar content, what was supossed to be a pituitary tumor. [revistaneurocirugia.com]

Anterior Pituitary Hypofunction

Enlarged sella turcica Headache, visual field defects (bitemporal hemianopsia- due to compression of optic chiasm), diplopia (due to oculomotor nerve palsies). what is Sheehan [brainscape.com]

The initial insult is caused by massive postpartum haemorrhage (PPH), leading to impaired blood supply to the pituitary gland, which has become enlarged during pregnancy. [nature.com]

Stage III are macroadenomas with enlargement and invasion of the floor or suprasellar extension. Stage IV is destruction of the sella. [cancer.gov]

Autoimmune Hypophysitis

This patient represents one of the few reported cases of recurrent hypophysitis and demonstrates that both pituitary enlargement and empty-sella can be seen in the same patient [ncbi.nlm.nih.gov]

Considerations include: pituitary adenoma macroadenomas are expected to enlarge the sella turcica craniopharyngioma (papillary type) suprasellar meningioma dural-based usually [radiopaedia.org]

A MRI disclosed a 1.0×0.9 cm sized cystic mass enlarging the sella turcica. [synapse.koreamed.org]