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112 Possible Causes for Enlarged Uterus, Metrorrhagia, Rarely Malignant

  • Uterine Fibroid

    malignant transformation of UL to uterine leiomyosarcoma.[ncbi.nlm.nih.gov] Pelvic magnetic resonance imaging revealed a markedly enlarged uterus with multiple fibroids.[ncbi.nlm.nih.gov] Symptoms and course MYOMA (FIBROIDS) OF THE UTERUS [MUOMA (FIBROMYOMA) UTERI] Mono - and metrorrhagia (polymenorrhea), pain, fluid serous leucorrhoea.[lecheniebolezni.com]

  • Endometrial Adenocarcinoma

    BACKGROUND: Primary endodermal sinus tumor of the endometrium is an extremely rare malignancy with few reports in the world literature.[ncbi.nlm.nih.gov] A physical or pelvic exam does not usually indicate much at all, although one’s doctor might feel a slight enlargement of the uterus.[thedoctorwillseeyounow.com] […] a uterine adenomatoid tumor and an endometrial adenocarcinoma, both chance findings in a 41-year-old woman undergoing hysterectomy because of a preoperative diagnosis of metrorrhagia[ncbi.nlm.nih.gov]

  • Hydatidiform Mole

    In extremely rare instances, hydatidiform moles develop into choriocarcinomas, which are highly malignant tumours.[britannica.com] RESULTS AND DISCUSSION: Theca lutein cysts and hydropic degeneration of villi, enlarged uterus and empty gestational sac, intrauterine hematoma significantly prevailed in[ncbi.nlm.nih.gov] Partial moles rarely develop into malignant GTD. Persistent gestational trophoblastic disease is GTD that is not cured by initial surgery.[cancer.org]

  • Endometrial Stromal Sarcoma

    Endometrial stromal sarcoma (ESS) is a rare malignant neoplasm of the uterus.[ncbi.nlm.nih.gov] A later scan showed further enlargement of the uterus (16 cm 13 cm 10 cm) with the intramural fibroid 10 cm 7 cm in posterior wall.[ncbi.nlm.nih.gov] The clinical presentation is comprised of nonspecific symptoms such as abdominal pain, vaginal bleeding, and progressive metrorrhagia in premenopausal women.[symptoma.com]

  • Ovarian Cyst

    They are very rarely malignant; however, women who develop dermoid cysts have a risk of them returning even after surgery.[trmbaby.com] […] by torsion or hemorrhage, and approximately 30% of these cysts can cause maternal androgen excess. [12] Follicular cysts can cause excess estradiol production, leading to metrorrhagia[emedicine.com] Although rare, ovarian malignancies do make up 1 percent of all malignancies found in children and adolescents, and must be considered.[pedclerk.bsd.uchicago.edu]

  • Endometrial Polyp

    malignity.[ncbi.nlm.nih.gov] An elderly woman presented with an enlarged uterus without uterine bleeding. The hysterectomy specimen contained a large, solitary intrauterine mass.[ncbi.nlm.nih.gov] A 69-year-old woman presented with metrorrhagia. The patient had been diagnosed 4 years before with infiltrating lobular breast carcinoma. Follow-up was uneventful.[ncbi.nlm.nih.gov]

  • Choriocarcinoma

    Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin.[ncbi.nlm.nih.gov] Cause Chromosomal mutation and aneuploidy, and history of previous molar pregnancy Symptoms Vaginal bleeding, rapidly enlarging uterus, pelvic pain, anemia, and hypertension[symptoma.com] […] gonadotropin (hCG) levels after removal of a hydatidiform mole, persistent unexplained metrorrhagia following spontaneous abortion or VTP, occasionally unexplained metrorrhagia[orpha.net]

  • Pregnancy

    Rare and recurrent thrombotic events in pregnancy increase the suspicion for occult malignancy.[ncbi.nlm.nih.gov] Urinary tract infections are common during pregnancy, probably because the enlarging uterus and hormones slow the flow of urine in the tubes that connect the kidneys to the[web.archive.org] uterus and hormones produced during pregnancy slow the flow of urine in the tubes that connect the kidneys to the bladder (ureters).[merckmanuals.com]

  • Anemia

    In patients with iron deficiency without anaemia, endoscopic investigation rarely detects malignancy.[doi.org] uterus pressing on the rectum is made worse by oral iron. 37 , 38 Recommendations for dosing oral iron vary from 60 to 200 mg of elemental iron per day. 2 , 21 This can be[bloodjournal.org] It is rare, but it should be noted that gastric or intestinal lymphoma sometimes presents as mild anemia with nonspecific gastrointestinal symptoms.[dx.doi.org]

  • Endometrial Hyperplasia

    Ovarian SCTs are usually smaller than 5 cm, unilateral and rarely malignant [ 2, 3, 18 ].[omicsonline.org] However, with each of the two 6-month courses of mifepristone (9 months apart) she developed massive simple endometrial hyperplasia and a markedly enlarged uterus.[ncbi.nlm.nih.gov] […] periods Pubertal menorrhagia Puberty bleeding N92.3 Ovulation bleeding Regular intermenstrual bleeding N92.4 Excessive bleeding in the premenopausal period Menorrhagia or metrorrhagia[web.archive.org]