Enlargement of the Liver Causes & Reasons

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Enlargement of the Liver Symptom Checker: Possible causes include Infantile Hepatic Hemangioendothelioma. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Infantile Hepatic Hemangioendothelioma

Physical examination revealed enlarged liver. Unenhanced abdominal CT showed enlargement of the liver with diffuse hypodensity. [ncbi.nlm.nih.gov]

[…] of the liver with diffuse hypodensity. [journals.lww.com]

The ultrasound examination revealed multiple hypoechoic liver lesions coexisting with an enlarged liver. [em-consulte.com]

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Infectious Mononucleosis

Symptoms Symptoms of EBV infection can include fatigue fever inflamed throat swollen lymph nodes in the neck enlarged spleen swollen liver rash Many people become infected [cdc.gov]

Other symptoms of mono are fatigue, decreased appetite, myalgias (body aches), rash, headache, swollen tonsils, enlarged spleen, enlarged liver and even night sweats. [mydrnow.com]

The main concern is the risk of an enlarged spleen rupturing. [mydrnow.com]

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Gaucher Disease

[britannica.com] Enlargement of the Liver Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications [symptoma.com]

The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the [en.wikipedia.org]

People in this group usually bruise easily due to low blood platelets and experience fatigue due to anemia They also may have an enlarged liver and spleen. [ninds.nih.gov]

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Hemochromatosis

Hemochromatosis can lead to two major liver issues: hepatomegaly and cirrhosis. Hepatomegaly is the enlargement of the liver and cirrhosis is the scarring of the liver. [hepb.org]

Hepatomegaly is enlargement of the liver beyond its normal size. [mountsinai.org]

This may eventually lead to serious problems such as: Arthritis Liver disease, including an enlarged liver, cirrhosis, liver cancer, or liver failure Damage to the pancreas [winchesterhospital.org]

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Glycogen Storage Disease Type 1

Symptoms appear in early childhood and include dangerously low blood sugar (hypoglycemia), delayed development, recurrent infection, and enlargement of the liver, spleen, [geneticdiseasefoundation.org]

[…] of the liver, heart, or striated muscle, including the … Medical dictionary syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting [medicine.academic.ru]

The major sign of GSD type 1 is the enlargement of the kidney and livers. In the first few weeks of life, the liver remains in its normal size. [symptoma.com]

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Glycogen Storage Disease

Symptoms and signs depend upon the exact type but can include enlargement of the liver (hepatomegaly), hypoglycemia, and muscle weakness or cramps eventually accompanied by [medicinenet.com]

Fats get stored in the liver along with the glycogen, which leads to the enlargement of the liver. [agsdus.org]

The conditions may affect the liver or the skeletal (striated) muscle, both primary glycogen storage sites. [medicinenet.com]

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Glycogen Storage Disease Type 6

It is characterized by enlargement of the liver (hepatomegaly), moderately low blood sugar (hypoglycemia), elevated levels of acetone and other ketone bodies in the blood [rarediseases.org]

These patients present with hepatomegaly (liver enlargement) and growth retardation early in childhood. [agsdus.org]

The first sign is usually an enlarged liver (hepatomegaly). [ghr.nlm.nih.gov]

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Glycogen Storage Disease Type 3

As they get older, children with this condition typically develop an enlarged liver (hepatomegaly). [ghr.nlm.nih.gov]

The symptoms of disease in the liver group are similar, ranging from symptomatic hypoglycemia and ketoacidosis to largely asymptomatic enlargement of the liver (hepatomegaly [britannica.com]

In babies, the liver may be enlarged and lab studies to look at liver function may be abnormal. [thinkgenetic.com]

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Cholesterol Ester Storage Disease

Enlarged liver or hepatomegaly can be detected with a CT or computed tomography scan. The calcification of adrenal glands can be detected with radiological techniques. [medindia.net]

These diseases cause high levels of fats in the blood and an enlarged liver. [msdmanuals.com]

[…] and/or spleen enlargement; or other types of liver disease such as steatosis, fibrosis, or cirrhosis. [accessmedicine.mhmedical.com]

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Glycogen Storage Disease Type 4

Ultra-sonography reveals an enlarged liver, ascites and splenomegaly. [symptoma.com]

The symptoms of disease in the liver group are similar, ranging from symptomatic hypoglycemia and ketoacidosis to largely asymptomatic enlargement of the liver (hepatomegaly [britannica.com]

Within the first months of life, affected infants have difficulty gaining weight and growing at the expected rate (failure to thrive) and develop an enlarged liver (hepatomegaly [ghr.nlm.nih.gov]

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Mauriac's Syndrome

[…] hepatopathy (GH) The other main cause of liver enlargement and deranged liver tests related in diabetes mellitus is fatty liver. [qingningbian.blogspot.com]

A repeat liver ultrasound showed an enlarged liver with a hyperechoic echotexture. [ijcasereportsandimages.com]

As a result, the liver becomes enlarged. [archive.jsonline.com]

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Niemann-Pick Disease

The disease primarily affects the: liver spleen brain bone marrow This leads to enlargement of the spleen and neurologic problems. [healthline.com]

As is typical for NPA/B disease, Joseph has splenomegaly (enlargement of the spleen) and hepatomegaly (enlargement of the liver) and his lungs are also affected. [globalgenes.org]

liver or spleen. [healthline.com]

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Congenital Hepatic Fibrosis

A to Z definitions A liver abnormality common in children with ARPKD; it may lead eventually lead to enlargement of the liver and spleen. [pkdcure.org]

[…] nodular enlarged liver. [kjim.org]

Synopsis hepatomegaly (hard and enlarged liver) portal hypertension secondary infections with systemic sepsis islands of normal parenchyma surounded by fibrous septa duct-like [humpath.com]

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Neonatal Hepatitis

Symptoms common to liver disease often occur including yellowing of the whites of the eyes and the skin (jaundice), enlargement of the liver (hepatomegaly) and unusually dark [hekim.org]

Abdominal ultrasound (US) showed an enlarged liver with a normal structure. [hindawi.com]

A computed tomography (CT) scan of the thorax and abdomen confirmed a severely enlarged homogeneous liver. [hindawi.com]

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Juvenile-Onset Still Disease

Predominantly extra-articular manifestations like high fevers, rheumatic rash, enlargement of the liver and spleen, enlargement of the lymph nodes, and anemia. [en.wikipedia.org]

Signs and symptoms The disease typically presents with joint pain, high fevers, a salmon-pink rash, enlargement of the liver and spleen, swollen lymph nodes, and an increased [checkrare.com]

Other Still's disease symptoms.are: Poor appetite, nausea, and weight loss are common There is also commonly swelling of the lymph glands, enlargement of the spleen and liver [medicinenet.com]

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Myelofibrosis

My husband was diagnosed with MF in 2004, no symptoms, JAK neg, just enlarged spleen and liver. [csn.cancer.org]

The result is extensive scarring in your bone marrow, leading to severe anemia, weakness, fatigue, and often, an enlarged spleen and liver.'' [cmleukemia.com]

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Wolman Disease

Bilateral echogenicity of the adrenal glands and enlargement of the liver on prenatal ultrasound should merit consideration of Wolman's disease. [obgyn.onlinelibrary.wiley.com]

Symptoms Symptoms include enlargement of the liver and spleen, an excessive amount of fat in the stools, distention of the abdomen and adrenal calcification that appears in [cedars-sinai.edu]

[…] of the liver and spleen, abdominal distension, steatorrhea, cachexia, and usually death in infancy. [yourdictionary.com]

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Polycystic Liver Disease

Polycystic liver disease can result in massive enlargement of the liver with resultant debilitating symptoms of abdominal pain, chronic fatigue, and severely compromised functional [ncbi.nlm.nih.gov]

Magnetic resonance imaging and computed tomography showed bilateral enlarged polycystic kidneys and a massive polycystic liver (Fig. 1 ). [karger.com]

In adult polycystic liver disease, the liver gradually enlarges as it is replaced by cysts. The disease rarely produces symptoms or complications. [ncbi.nlm.nih.gov]

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Gaucher Disease Type 2

[…] spleen. 0002793 Dysphagia Poor swallowing Swallowing difficulties Swallowing difficulty [ more ] 0002015 Dystonia 0001332 Encephalopathy 0001298 Hepatomegaly Enlarged liver [rarediseases.info.nih.gov]

The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the [en.wikipedia.org]

There is great enlargement of the liver and spleen, bone marrow displacement, bleeding tendency, bronzing of the skin, and anaemia. Also known as cerebroside lipidosis. [medical-dictionary.thefreedictionary.com]

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Schnitzler Syndrome

[…] spleen and liver. [1] Schnitzler syndrome is considered an autoinflammatory disorder and is generally treated with anakinra, which inhibits interleukin 1. [en.wikipedia.org]

[…] age of chronic hives (urticaria) and periodic fever, bone pain and joint pain (sometimes with joint inflammation ), weight loss, malaise, fatigue, swollen lymph glands and enlarged [en.wikipedia.org]

[…] spleen or liver, elevated erythrocyte sedimentation rate, high levels of white blood cells, and findings of problems in bone imaging. [1] [2] In the Strasbourg criteria, [en.wikipedia.org]

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Hepatosplenic Lymphoma

When doctors start evaluating patients with HSTCL, they frequently find very low blood cell counts and abnormalities in liver function on blood tests; enlarged spleen and [tcllfoundation.org]

Not surprisingly, the most common presenting sign is hepatosplenomegaly, which is enlargement of the liver and/or spleen. [knowcancer.com]

liver on the CT-scans (of note: lymph nodes or other organs are very rarely enlarged or involved by the lymphoma); presence of abnormal cells in the blood through a specialized [tcllfoundation.org]

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Niemann-Pick Disease Type B

The main features of Niemann-Pick disease type B (NPD-B) are enlargement of the liver and spleen, and mild pulmonary involvement. [ncbi.nlm.nih.gov]

Niemann-Pick Type A / B [SMPD1]: Severe neurodegenerative condition, loss of brain function and enlargement of the liver and spleen, average life expectancy 2–3 years of age [jewishgeneticdiseases.org]

Failure to break down sphingomyelin causes an accumulation and enlargement of the liver and spleen. [npuk.org]

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Glycogen Storage Disease due to GLUT2 Deficiency

USG abdomen showed liver was enlarged, coarse with multiple hyperechoic micronodular lesions with bilateral bright & enlarged kidneys. [journalofpediatriccriticalcare.com]

[…] causes death(usually before age 2) #2 Pompe's Disease GLYCOGEN STORAGE DISEASE where Amylo-1,6-glucosidase is defective and have enlargement of liver(milder) and severe hypoglycemia [studystack.com]

Most patients have the typical combination of clinical symptoms: hepatomegaly secondary to glycogen accumulation, glucose and galactose intolerance, fasting hypoglycemia, [doi.org]

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Glycogen Storage Disease due to Glucose-6-Phosphat Transport Defect

The symptoms of disease in the liver group are similar, ranging from symptomatic hypoglycemia and ketoacidosis to largely asymptomatic enlargement of the liver (hepatomegaly [britannica.com]

Short stature & growth delay Abdomen protrusion Build up of glycogen and fat in the liver Enlarged liver and malignant/benign growths in the liver Yellow plaques on skin [en.wikibooks.org]

Hepatomegaly and liver problems [ edit ] Impairment of glycogenolysis also causes the characteristic enlargement of the liver (hepatomegaly) due to accumulation of glycogen [en.wikipedia.org]

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Glycogen Storage Disease due to Muscle Phosphorylase Kinase Deficiency

The symptoms of disease in the liver group are similar, ranging from symptomatic hypoglycemia and ketoacidosis to largely asymptomatic enlargement of the liver (hepatomegaly [britannica.com]

The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the [checkrare.com]

Common symptoms of the liver form include abnormal enlargement of the liver (hepatomegaly), unusually low levels of blood glucose (hypoglycemia), increase in blood ketones [rarediseases.org]

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Alcoholic Liver Disease

Altered consciousness, enlarged spleen and liver, as well as hypertension and development of esophageal varices are observed in severe cases. [symptoma.com]

Also known as alcoholic fatty liver disease. Often symptom-less, alcoholic fatty liver disease largely refers to the enlargement of the liver, and is generally painless. [the-alcoholism-guide.org]

Steatosis is characterized by an enlarged and inflamed liver. [alcoholrehab.com]

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Congenital Generalized Lipodystrophy Type 1

Additionally, congenital generalized lipodystrophy causes an abnormal buildup of fats in the liver (hepatic steatosis), which can result in an enlarged liver (hepatomegaly [ghr.nlm.nih.gov]

Furthermore, affected individuals may show umbilical prominence or even have umbilical hernia due to an enlarged liver. [symptoma.com]

[…] or an enlarged liver which arises from fatty liver and may lead to cirrhosis, muscle hypertrophy, lack of adipose tissue, splenomegaly, hirsutism (excessive hairiness) and [en.wikipedia.org]

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Portal Cirrhosis

In the early stages, liver enlargement may reflect fatty infiltration of liver cells (fatty cirrhosis) with necrosis and inflammation due to acute alcohol injury; progressive [medical-dictionary.thefreedictionary.com]

RESULTS: The patients with diffuse liver cancer showed enlarged liver and obvious echo of nodules. [ncbi.nlm.nih.gov]

[…] with hepatic enlargement (the liver may shrink when complete loss of function is present). [medical-dictionary.thefreedictionary.com]

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Mucopolysaccharidosis 2

[…] of the liver and spleen. [hunterpatients.com]

Individuals with this disorder may experience the following signs: abnormal retina, heart murmur and leaky heart valves, enlarged liver (hepatomegaly) enlarged spleen (splenomegaly [secure.ssa.gov]

[…] of the liver and spleen and decreased range of motion and mobility. [efpia.eu]

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Glycogen Storage Disease Type 9

The initial features are usually an enlarged liver (hepatomegaly) and slow growth. Affected children are often shorter than normal. [ghr.nlm.nih.gov]

The most common symptoms are enlarged liver, growth retardation, mild delay in motor development, and elevated blood lipids (fats). [agsdus.org]

When GSD IX affects the liver, the signs and symptoms typically begin in early childhood. [ghr.nlm.nih.gov]

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