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2,854 Possible Causes for Enlargement of the Liver

  • Gaucher Disease

    People in this group usually bruise easily due to low blood platelets and experience fatigue due to anemia They also may have an enlarged liver and spleen.[] Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis[] [] Enlargement of the Liver Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications[]

  • Chronic Lymphocytic Leukemia

    The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[] […] nodes; stage II, lymphocytosis with enlarged spleen or liver or both; stage III, lymphocytosis with anemia; and stage IV:lymphocytosis with thrombocytopenia.[] Symptoms of CLL may include: Abnormal bruising (if platelets are low) Enlarged lymph nodes, liver, or spleen Excessive sweating, night sweats Fatigue Fever Infections that[]

  • Mucopolysaccharidosis

    […] of the liver and spleen and decreased range of motion and mobility.[] Symptoms include dwarfism, severe bone disease, including facial deformity, degenerative joint disease, enlarged liver and eye cloudiness.[] Additional findings include short stature, heart abnormalities, breathing irregularities, liver and spleen enlargement (hepatosplenomegaly), and/or neurological abnormalities[]

  • Hodgkin's Disease

    Symptoms Painless local or disseminated lymph node enlargement, swelling of liver and spleen, unexplained fever, and diffuse itch.[] Hepatosplenomegaly: the enlargement of both the liver and spleen caused by the same disease.[] […] nodes and inflammation of some body organs such as the spleen and liver.[]

  • Cytomegalovirus Infection

    […] spleen and liver, jaundice , and a rash caused by bleeding underneath the skin.[] […] of the liver and spleen with jaundice, to stillbirth or neonatal/infant death.[] , poorly-functioning liver, with jaundice Low blood platelet count Abnormal white blood cell levels (high or low) Enlarged spleen Anemia Children affected by Cytomegalic Inclusion[]

  • Progressive Familial Intrahepatic Cholestasis

    […] of the liver and spleen that is not normal Fatigue (tired all of the time) Poor feeding, upset belly, and throwing up Problems that may arise include: Problems absorbing[] Excess bile salts are stored in the liver cells and leak into the bloodstream, resulting in severe itching, jaundice, and an enlarged liver.[] (portal hypertension), and an enlarged liver and spleen (hepatosplenomegaly).[]

  • Niemann-Pick Disease Type C

    Accumulation of cholesterol inside lysosomes leads to fatal symptoms, such as progressive nerve degeneration, and enlargement of the liver and spleen.[] After taking two-month-old Kamryn to the doctor for a bloated stomach, the Brumbeloe’s learned that she had an enlarged spleen and liver and were referred to the Children’[] Symptoms Enlarged spleen and liver, prolonged jaundice, progressive loss of motor skills, difficultly walking, slurred speech, swallowing problems, seizures and dementia.[]

  • Essential Thrombocythemia

    Because kinases are very powerful drivers of cell growth, this genetic change leads to an elevation in blood counts and enlargement of the liver and spleen.[] Your health care provider may notice an enlarged liver or spleen on physical examination.[]

  • Lipodystrophy

    Children can also develop periorbital edema (swelling around the eye sockets), and edema (clubbing) of finger and/or toes, and gradual enlargement of the liver, along with[] There may be abnormal breakdown of fats with loss of weight, excessive levels of fats in the blood, raised blood sugar levels, enlargement of the liver and abnormal thyroid[] This condition results in enlargement of the liver and kidneys.[]

  • Generalized Lipodystrophy

    Additionally, congenital generalized lipodystrophy causes an abnormal buildup of fats in the liver (hepatic steatosis), which can result in an enlarged liver (hepatomegaly[] Consequently, affected individuals may develop abnormal enlargement of the muscles (muscular hypertrophy) or the liver (hepatomegaly).[] Infants usually develop an enlarged liver. Young kids have problems controlling their blood sugar and triglyceride levels.[]

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