Gaucher Disease
People in this group usually bruise easily due to low blood platelets and experience fatigue due to anemia They also may have an enlarged liver and spleen.[ninds.nih.gov]
Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis[ncbi.nlm.nih.gov]
[britannica.com] Enlargement of the Liver Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications[symptoma.com]
Chronic Lymphocytic Leukemia
The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov]
[…] nodes; stage II, lymphocytosis with enlarged spleen or liver or both; stage III, lymphocytosis with anemia; and stage IV:lymphocytosis with thrombocytopenia.[ncbi.nlm.nih.gov]
Symptoms of CLL may include: Abnormal bruising (if platelets are low) Enlarged lymph nodes, liver, or spleen Excessive sweating, night sweats Fatigue Fever Infections that[nlm.nih.gov]
Mucopolysaccharidosis
[…] of the liver and spleen and decreased range of motion and mobility.[efpia.eu]
Symptoms include dwarfism, severe bone disease, including facial deformity, degenerative joint disease, enlarged liver and eye cloudiness.[vetgen.com]
Additional findings include short stature, heart abnormalities, breathing irregularities, liver and spleen enlargement (hepatosplenomegaly), and/or neurological abnormalities[rarediseases.org]
Hodgkin's Disease
Symptoms Painless local or disseminated lymph node enlargement, swelling of liver and spleen, unexplained fever, and diffuse itch.[symptoma.com]
Hepatosplenomegaly: the enlargement of both the liver and spleen caused by the same disease.[slideshare.net]
[…] nodes and inflammation of some body organs such as the spleen and liver.[articles.latimes.com]
Cytomegalovirus Infection
[…] spleen and liver, jaundice , and a rash caused by bleeding underneath the skin.[babycenter.com]
[…] of the liver and spleen with jaundice, to stillbirth or neonatal/infant death.[ideas.health.vic.gov.au]
, poorly-functioning liver, with jaundice Low blood platelet count Abnormal white blood cell levels (high or low) Enlarged spleen Anemia Children affected by Cytomegalic Inclusion[ada.com]
Progressive Familial Intrahepatic Cholestasis
[…] of the liver and spleen that is not normal Fatigue (tired all of the time) Poor feeding, upset belly, and throwing up Problems that may arise include: Problems absorbing[cincinnatichildrens.org]
Excess bile salts are stored in the liver cells and leak into the bloodstream, resulting in severe itching, jaundice, and an enlarged liver.[sema4genomics.com]
(portal hypertension), and an enlarged liver and spleen (hepatosplenomegaly).[ghr.nlm.nih.gov]
Niemann-Pick Disease Type C
Accumulation of cholesterol inside lysosomes leads to fatal symptoms, such as progressive nerve degeneration, and enlargement of the liver and spleen.[sciencedaily.com]
After taking two-month-old Kamryn to the doctor for a bloated stomach, the Brumbeloe’s learned that she had an enlarged spleen and liver and were referred to the Children’[childrensinn.org]
Symptoms Enlarged spleen and liver, prolonged jaundice, progressive loss of motor skills, difficultly walking, slurred speech, swallowing problems, seizures and dementia.[dailymail.co.uk]
Essential Thrombocythemia
Because kinases are very powerful drivers of cell growth, this genetic change leads to an elevation in blood counts and enlargement of the liver and spleen.[rarediseases.org]
Your health care provider may notice an enlarged liver or spleen on physical examination.[nlm.nih.gov]
Lipodystrophy
Children can also develop periorbital edema (swelling around the eye sockets), and edema (clubbing) of finger and/or toes, and gradual enlargement of the liver, along with[autoinflammatory.org]
There may be abnormal breakdown of fats with loss of weight, excessive levels of fats in the blood, raised blood sugar levels, enlargement of the liver and abnormal thyroid[medical-dictionary.thefreedictionary.com]
This condition results in enlargement of the liver and kidneys.[epainassist.com]
Generalized Lipodystrophy
Additionally, congenital generalized lipodystrophy causes an abnormal buildup of fats in the liver (hepatic steatosis), which can result in an enlarged liver (hepatomegaly[ghr.nlm.nih.gov]
Consequently, affected individuals may develop abnormal enlargement of the muscles (muscular hypertrophy) or the liver (hepatomegaly).[rarediseases.org]
Infants usually develop an enlarged liver. Young kids have problems controlling their blood sugar and triglyceride levels.[webmd.com]