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263 Possible Causes for Enlargement of the Liver, Periorbital Edema

  • Infectious Mononucleosis

    edema, and lymphadenopathy (which often involves the posterior cervical chain). 2 It may also be associated with hepatomegaly and splenomegaly.[] Other symptoms of mono are fatigue, decreased appetite, myalgias (body aches), rash, headache, swollen tonsils, enlarged spleen, enlarged liver and even night sweats.[] Other rare observation may include bilateral periorbital edema, conjunctivitis or eyelid edema.[]

  • Lipodystrophy

    Children can also develop periorbital edema (swelling around the eye sockets), and edema (clubbing) of finger and/or toes, and gradual enlargement of the liver, along with[] There may be abnormal breakdown of fats with loss of weight, excessive levels of fats in the blood, raised blood sugar levels, enlargement of the liver and abnormal thyroid[] This condition results in enlargement of the liver and kidneys.[]

  • Hodgkin's Disease

    Symptoms Painless local or disseminated lymph node enlargement, swelling of liver and spleen, unexplained fever, and diffuse itch.[] Hepatosplenomegaly: the enlargement of both the liver and spleen caused by the same disease.[] […] nodes and inflammation of some body organs such as the spleen and liver.[]

  • Tularemia

    In addition, involvement of larynx, oropharynx, and retropharynx; presence of periorbital edema; and neck abscess formation were evaluated using CECT.[] In case of typhoidal tularemia, in addition to above mentioned symptoms, individuals also experience pneumonia, enlarged spleen and liver, extreme exhaustion and vomiting[] In the oculoglandular form, fever, lymphadenopathy, periorbital edema, conjunctival injection, and chemosis were found.[]

  • Sulfasalazine

    edema, optic neuritis, transient myopia, tinnitus GI: nausea, vomiting, abdominal pain, stomatitis, glossitis, pancreatitis, dry mouth, anorexia, pseudomembranous colitis[] […] of the liver, spleen, and several peripheral lymph nodes.[] edema, conjunctival and scleral injection, and alopecia .[]

  • Salmonella Typhi

    Bronchopneumonia, proptosis and periorbital edema resolved with systemic antibiotic therapy but the patient developed bilateral phthisis bulbi.[] Pink spots appear on the chest; examinations will usually reveal enlargement of the liver and spleen.[] The spleen and liver are enlarged (hepatosplenomegaly) and tender. Death occurs in 10% to 30% of untreated cases Wikipedia .[]

  • Phenytoin Toxicity

    edema Gastrointestinal/abdomen findings may include the following: Right upper quadrant tenderness Hepatomegaly Splenomegaly Nausea Vomiting Metabolic findings in patients[] Imaging tests will reveal hepatomegaly or enlargement of the liver and splenomegaly or enlargement of the spleen.[] […] multiple doses Skin findings may include the following: Acne Rashes, can be mild, morbilliform, scarlatinoid or as severe as Stevens-Johnson syndrome Jaundice Facial or periorbital[]

  • Human Herpesvirus 6

    With the fever, some children exhibit bilateral periorbital edema in the prodrome.[] Other complications include ear infections, exceptionally high fever, respiratory distress, enlargement of the liver or spleen and hepatitis.[] Reactivation can create a “mono-like” illness in adults resulting in fatigue, fever, swollen lymph nodes, enlarge liver and spleen, or encephalitis and mental changes.[]

  • Sterile Multifocal Osteomyelitis with Periostitis and Pustulosis

    TNF receptor associated periodic syndrome TNFRSF1A 12p13 p55 TNF receptor AD Prolonged fever episodes: 1-3 weeks Periorbital edema, monocytic fasciitis.[] Hepatomegaly MedGen UID: 42428 • Concept ID: C0019209 • Finding Abnormal enlargement of the liver.[] Splenomegaly MedGen UID: 52469 • Concept ID: C0038002 • Finding Abnormal enlargement of the spleen.[]

  • Glomerulonephritis

    edema and hypertension Adults : may have atypical presentation with sudden hypertension, edema and elevated BUN; 60% recover, others develop rapidly progressive glomerulonephritis[] […] of the liver 20.  Hematuria: dark brown or smoky urine  Oliguria: urine output is 400 ml/day  Edema: starts in the eye lids and face then the lower and upper limbs then[] Physical exam revealed an afebrile man with lower extremity edema extending to the knee, periorbital edema , and a small amount of ascites . Drug history was negative.[]

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