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1,010 Possible Causes for Enlargement of the Spleen, Foul Smelling Stool, Irritability, Liver Biopsy Abnormal, Pruritus

  • Progressive Familial Intrahepatic Cholestasis

    […] liver and spleen (hepatosplenomegaly).[ghr.nlm.nih.gov] […] progressive familial intrahepatic cholestasis (PFIC) Jaundice Scleral icterus Cutaneous jaundice Dark urine Physical See the list below: Pruritus Scratching Cutaneous mutilation Irritability[emedicine.medscape.com] Also, these patients produce copious amounts of foul-smelling stool, which may persist following liver transplant.[symptoma.com] Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders.[ncbi.nlm.nih.gov] Foul-smelling, high volume stools and failure to thrive are also hallmarks for PFIC1[ 35 ].[wjgnet.com]

  • Primary Biliary Cirrhosis

    Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] Primary Sclerosing Cholangitis Wilson’s Disease Primary biliary cirrhosis (or PBC) is a condition in which the bile ducts (ducts that remove bile from the liver) become irritated[nyp.org] Biopsy of the liver tissue is also required to confirm the presence of PBC and to determine the extent of the disease.[symptoma.com] : Osteoporosis and other metabolic bone diseases Gallstones and bile duct stones Liver cancer Steatorrhea (inability of the body to absorb fat, leading to loose, greasy, foul-smelling[everydayhealth.com] Intense pruritus can be itself an indication to liver transplantation, in extreme cases leading to suicide.[ncbi.nlm.nih.gov]

  • Biliary Atresia

    Other symptoms include: Dark yellow or brown urine Gray or white stools Swollen belly Enlarged liver or spleen Kasai procedure The most common treatment for babies with biliary[share.upmc.com] Hepatomegaly Splenomegaly Weight loss Irritability Infant passes clay colored stools because of absence of bile or bilirubin.[symptoma.com] […] well as a CBC (complete blood count) Liver biopsy (bi-op-see) Ultrasound , to identify any clear abnormalities in the liver or in other organs A nuclear scan, which tracks[chp.edu] Other symptoms may include: Dark urine Enlarged spleen Floating stools Foul-smelling stools Pale or clay-colored stools Slow growth Slow or no weight gain Exams and Tests[ufhealth.org] Generalized pruritus secondary to cholestasis is a difficult dermatologic condition to treat.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    These include: an enlarged liver or spleen, anaemia , cirrhosis , female sex and older age. Increasing bilirubin also correlates with disease progression.[myvmc.com] This was observed in patients with PSC with and without irritable bowel disease and was distinct from IBD.[healio.com] Liver function tests then reveal more abnormalities.[chp.edu] Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[ncbi.nlm.nih.gov] Signs and symptoms that may appear as the disease progresses include: Pain in the upper right part of the abdomen Fever Chills Night sweats Enlarged liver Enlarged spleen[mayoclinic.org]

    Missing: Foul Smelling Stool
  • Malignant Neoplasm of Pancreas

    […] in enlargement of the spleen (splenomegaly).[merckmanuals.com] These symptoms are commonly mistaken for other conditions such as irritable bowel syndrome, colitis, asthma, or menopause.[netrf.org] Observe and report any evidence of diarrhea or frothy, floating, foul-smelling stools (an indication of steatorrhea) because an adjustment in the enzyme replacement therapy[medical-dictionary.thefreedictionary.com] Steatorrhea (very foul-smelling stool that floats). Gallstones . Yellowing of the skin and whites of the eyes. Weight loss for no known reason.[cancer.gov] Side effects of this radiation therapy may include vomiting, diarrhea, fatigue, and skin irritations resembling a sunburn.[britannica.com]

    Missing: Liver Biopsy Abnormal
  • Secondary Biliary Cirrhosis

    It is marked by jaundice, abdominal pain, steatorrhea, and enlargement of the liver and spleen. congestive cirrhosis cirrhosis resulting from increased hepatic venous pressure[medical-dictionary.thefreedictionary.com] A liver biopsy should be performed confirm the diagnosis.[healthcentral.com] […] skin Fatigue Jaundice symptoms like yellowing of the eyes and skin Other manifestations may include: Darkening of exposed areas of the skin Fever Bone pain Pale-colored, foul-smelling[digestion.ygoy.com] SECONDARY BILIARY CI RR H OS I S Symptoms Clinical features · Jaundice · Pruritus · Biliary colics.[medicscientist.com] Enlarged spleen (splenomegaly).[mayoclinic.org]

  • Benign Recurrent Intrahepatic Cholestasis

    It is first noted in infants with loose, foul-smelling stools, evidence of malnutrition, yellow jaundice, enlarged liver and spleen.[wohproject.org] Episodes generally begin in the late teens or early twenties and may be accompanied by jaundice , severe itchiness, a vague feeling of discomfort (malaise), irritability,[rarediseases.info.nih.gov] The course of serum parameters was accompanied by a dramatic clinical improvement of the patients symptoms (pruritus, jaundice, fatigue etc.).[ncbi.nlm.nih.gov] Other general signs and symptoms that occur during these episodes include a vague feeling of discomfort (malaise), irritability, nausea, vomiting, and a lack of appetite.[ghr.nlm.nih.gov] Liver biopsy is generally performed in all suspected cases of BA and is also used to rule-out other causes of neonatal cholestasis.[wjgnet.com]

  • Hemochromatosis

    The clinical manifestations include skin pigmentation, diabetes mellitus , enlargement of the spleen and liver , cirrhosis , heart failure , arthritis , and general weakness[britannica.com] Early symptoms may include lethargy and weakness, irritability, depression, joint pain, yellowish skin, and loss of body hair.[massgeneral.org] Liver biopsy — while it is usually not necessary to confirm the diagnosis by examination of a liver biopsy specimen for iron accumulation, a biopsy is often done to help determine[labtestsonline.org] This reference provides food for thought for dermatologists with prurigo or generalized pruritus patients.[clinicaladvisor.com] Making the Diagnosis If a doctor suspects hemochromatosis, a physical examination is done to check for an enlarged liver, enlarged spleen, or skin colour changes.[medbroadcast.com]

    Missing: Foul Smelling Stool
  • Blastocystis Hominis

    […] liver and / or spleen, rashes, itching, and joint pains and swelling.[naturalhealthtechniques.com] The aim of this study was to analyze genotypes of B. hominis isolates obtained from the healthy individuals and patients with irritable bowel syndrome-diarrhea (IBS-D).[ncbi.nlm.nih.gov] Foul smelling stools Excessive flatulence Frequent nausea Itchy anal/rectal area Visible mucus or pus in stools Frequent or intermittent diarrhoea Difficulty gaining weight[custommedicine.com.au] […] smartnutrition.co.uk Blastocystis has been found to produce gastrointestinal cramps, vomiting, sleeplessness, nausea, weight loss, lassitude, dizziness, flatus, anorexia, and pruritus[smartnutrition.co.uk] This study was designed to examine stool specimens of irritable bowel syndrome (IBS) patients for Blastocystis hominis, a common intestinal parasite.[ncbi.nlm.nih.gov]

    Missing: Liver Biopsy Abnormal
  • Autoimmune Hepatitis

    A pediatric specialist may find an enlarged liver or spleen during an examination of your child’s body. Blood tests.[rileychildrens.org] , acne, back-ne, irritability, a little spontaneous rage, emotionality...good times, good times.[healingwell.com] A 61-year-old male was referred to our hospital because of abnormal liver enzyme levels after initial diagnosis of CAEBV had been made by laboratory tests and liver biopsy[ncbi.nlm.nih.gov] Fatigue Abdominal pain Joint pain Itching (pruritus) Jaundice An enlarged liver Abnormal blood vessels on the skin (spider angiomas) Nausea and vomiting Loss of appetite Skin[columbiasurgery.org] Enlargement of the spleen could mean that your child’s symptoms are caused by an infection.[nyulangone.org]

    Missing: Foul Smelling Stool

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