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149 Possible Causes for Enlargement of the Spleen, Hashimoto's Thyroiditis, Splenomegaly

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[cancer.unm.edu] Patients may sometimes present with hepatomegaly, splenomegaly or both and/or hemolytic anemia.[radiopaedia.org] After 3 years, he presented a CLL progression with worsening lymphocytosis, anemia, thrombocytopenia, increased splenomegaly, and lymphadenopathies.[ncbi.nlm.nih.gov]

  • Primary Biliary Cirrhosis

    thyroiditis.[ncbi.nlm.nih.gov] Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org]

  • Sjogren's Syndrome

    ’s) thyroiditis (inflammation of the thyroid), enlargement of the liver, and inflammation of the pancreas.[britannica.com] On admission, she presented with anemia, elevated C-reactive protein levels, anasarca, and hepato-splenomegaly.[ncbi.nlm.nih.gov] Family history is notable for Hashimoto's thyroiditis in her mother. Physical exam shows dry oral mucosa and enlargement of the parotid glands.[medbullets.com]

  • Hemochromatosis

    Prevalences of Hashimoto's thyroiditis, rheumatoid arthritis, and ankylosing spondylitis were 8.1% (95% CI: [5.1, 12.5]), 1.7% [0.6, 4.6], and 0.0085 [0.0015, 0.0337], respectively[ncbi.nlm.nih.gov] The clinical manifestations include skin pigmentation, diabetes mellitus , enlargement of the spleen and liver , cirrhosis , heart failure , arthritis , and general weakness[britannica.com] Regression on SF revealed significant associations: TS; male sex; age; GGT; transfusion units (positive); and splenomegaly (negative) (p 0.0001, 0.0016, 0.0281, 0.0025, 0.0001[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    […] gland to produce too much thyroid hormone), Hashimoto thyroiditis (in which the immune system attacks the thyroid gland, causing it to secrete less and less thyroid hormone[diabetesselfmanagement.com] Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Enlargement of liver and spleen (hepatosplenomegaly) may also occur, accompanied by yellow discoloration of the skin (jaundice) or pallor.[diagnose-me.com]

  • Non-Hodgkin Lymphoma

    Autoimmune disorders: eg, Sjögren's syndrome and Hashimoto's thyroiditis, promote the development of MALT and predispose patients to subsequent lymphoid malignancies.[patient.info] They can also find an enlarged liver or spleen. A number of tests can be used to diagnose NHL. Your lymph nodes will swell any time your body is fighting an infection.[healthline.com] A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue.[icd9data.com]

  • Autoimmune Hepatitis

    Abstract Hashimoto thyroiditis (HT) is the most common pediatric autoimmune endocrine disorder.[ncbi.nlm.nih.gov] A pediatric specialist may find an enlarged liver or spleen during an examination of your child’s body. Blood tests.[rileychildrens.org] Physical exam was remarkable for digital clubbing, splenomegaly and orthodeoxia.[ncbi.nlm.nih.gov]

  • Prolymphocytic Leukemia

    However, the generalized lymphadenopathy and splenomegaly did not improve. The patient underwent splenectomy to palliate abdominal distension and hypersplenism.[ncbi.nlm.nih.gov] PATIENT FINDINGS: An 89-year-old woman who had been treated for Hashimoto's thyroiditis for 20 years presented with a progressively enlarging thyroid mass accompanied by dyspnea[ncbi.nlm.nih.gov] Enlarged lymph nodes in PLL. In HCL, hairy cells build up more often in the spleen and bone marrow and may not cause noticeable lymph node swelling.[cancer.net]

  • Graves Disease

    Needle aspiration from the nodule yielded evidence of Hashimoto's thyroiditis. The patient also tested strongly positive for antithyroid peroxidase antibodies.[ncbi.nlm.nih.gov] Symptoms may include: Low birth weight Small or abnormally shaped head Poor weight gain despite adequate caloric intake Enlarged liver and spleen Goiter Fast heartbeat (which[stanfordchildrens.org] The work-up for secondary causes was negative with the exception of the CT scan findings of thymus enlargement, mild splenomegaly, and multiple sub-centimeter (ranging 5 to[casesjournal.biomedcentral.com]

  • Hyperthyroidism

    KEYWORDS: Hashimoto's thyroiditis; hyperthyroidism; pregnancy; systolic arterial hypertension[ncbi.nlm.nih.gov] Symptoms may include: Low birth weight Small or abnormally shaped head Poor weight gain despite adequate caloric intake Enlarged liver and spleen Goiter Fast heartbeat (which[stanfordchildrens.org] There may also be lymphoid hyperplasia including splenomegaly and an enlarged thymus.[patient.info]

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